A5089614459- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Pituitary Gland Disorders and Treatments
- Oral and Maxillofacial Pathology
- Vaccine Coverage and Hesitancy
- Biomedical Ethics and Regulation
- Dental Radiography and Imaging
- Health Systems, Economic Evaluations, Quality of Life
Direção Geral do Território
2021-2022
Universidade Nova de Lisboa
2022
National School of Public Health
2022
Administração Regional de Saúde de Lisboa e Vale do Tejo
2022
Universidade do Porto
2012
We developed a case-case study to compare mRNA vaccine effectiveness against Delta versus Alpha coronavirus variants. used data on 2,097 case-patients with PCR-positive severe acute respiratory syndrome 2 infections reported in Portugal during May-July 2021. estimated the odds of breakthrough infection Delta-infected Alpha-infected patients by using conditional logistic regression adjusted for age group and sex matched week diagnosis. compared reverse-transcription PCR cycle threshold values...
Introduction: Early reports showed that Omicron (BA.1) SARS-CoV-2 could be less severe. However, the magnitude of risk reduction hospitalization and mortality infections compared with Delta (B.1.617.2) is not yet clear. This study compares severe disease among patients infected variant in Portugal.Methods: We conducted a cohort individuals diagnosed infection between 1st 29th December 2021. Cases were positive PCR test notified to national surveillance system. variants classified first by...
Abstract Introduction Early reports showed that Omicron (BA.1) SARS-CoV-2 could be less severe. However, the magnitude of risk reduction hospitalization and mortality infections compared with Delta (B.1.617.2) is not yet clear. This study compares severe disease among patients infected variant in Portugal. Methods We conducted a cohort individuals diagnosed infection between 1 st 29 th December 2021. Cases were positive PCR test notified to national surveillance system. variants classified...
Abstract Background Clinical decision support systems are known to improve adherence clinical practice guidelines and patient outcomes by providing clinicians with timely, accurate, appropriate knowledge. Objective This study investigates the perceived usefulness practical implementation of UpHill Route v3, a personalized digital care pathway (PDCP) system, in enhancing decision-making management across various settings. Methods A mixed-methods retrospective was conducted among medical...
Abstract Background The SARS-CoV-2 Delta variant (B.1.617.2), initially identified in India, has become predominant several countries, including Portugal. Few studies have compared the effectiveness of mRNA vaccines against versus Alpha concern (VOC) and estimated variant-specific viral loads vaccine infection breakthroughs cases. In context dominance, this information is critical to inform decision-makers regarding planning restrictions vaccination roll-out. Methods We developed a case-case...
Abstract Introduction The B.1.617.2 variant (Delta) was associated with increased transmissibility and lower vaccine effectiveness than the B.1.1.7 (Alpha). However, effect of on disease severity remains unclear. This study aims to assess whether infection a higher risk serious illness, compared other co-circulating variants, measured through hospitalization death by COVID-19 in Portugal. Methods We conducted matched cohort adult individuals diagnosed SARS-CoV-2/COVID-19 between March 29...
<sec> <title>BACKGROUND</title> Clinical decision support systems (CDSS) are known to improve adherence clinical practice guidelines and patient outcomes by providing clinicians with timely, accurate, appropriate knowledge. </sec> <title>OBJECTIVE</title> This study investigates the perceived usefulness practical implementation of UpHill Route v3, a personalized digital care pathway (PDCP) system, in enhancing decision-making management across various settings. <title>METHODS</title> A...
3o doente, houve apoplexia do tumor hipofisario, com criterios de hipopituitarismo ao diagnostico (HbA1c 9,3%, IGF1 38,8 ng/ml). Tratada a CAD, nao necessitou tratamento hipoglicemiante, estando atualmente medicado levotiroxina e prednisolona aguardar evolucao da lesao. Cetoacidose diabetica, secundaria deficite relativo ou absoluto insulina excesso hormonas contrarreguladoras, rara como manifestacao acromegalia (1%). Na nossa populacao representou 6,4% (N = 47). O efeito GH no metabolismo...