Canine heartworm infections were frequently diagnosed in Brazil before the new millennium. After year 2000, frequency of diagnosis showed a sharp decline; however, few years later, evidence indicated that parasite was still present and canine infection rates seemed to be increasing. Therefore, an updated survey prevalence conducted several locations south, southeast, northeast Brazil.Dogs from 15 having previously reported high included according defined criteria, including absence treatment...

Canine heartworm infections were frequently diagnosed in Brazil before the new millennium. After year 2000, frequency of diagnosis showed a sharp decline; however, few years later, evidence indicated that parasite was still present and canine infection rates seemed to be increasing. Therefore, an updated survey prevalence conducted several locations south, southeast, northeast Brazil. Dogs from 15 having previously reported high included according defined criteria, including absence...

Abstract Objective —To determine whether serum C-reactive protein (CRP) concentration is high in dogs with multicentric lymphoma, CRP changes response to chemotherapy, and can be used as a marker for relapse lymphoma. Design —Cohort study. Animals —20 lymphoma 8 healthy control undergoing chemotherapy cyclophosphamide, vincristine, prednisone (CVP) or methotrexate, L-asparaginase (VCMA) 20 other dogs. Procedures —Serum was measured weekly during the first month of then at 3-week intervals...

Oclacitinib is a Janus kinase (JAK) 1 enzyme inhibitor and blocks JAK1-dependent cytokines used to control pruritus. Studies available in cats are very limited as there potential role for oclacitinib the of pruritus this specie, aim study was evaluate safety clinical effects oral maleate healthy cats. Thirty mixed-breed weighing from 2.1 5.3 kg each were randomly allocated three treatment groups 10 animals each. Cats two received at mg/kg or 2 q 12 h orally 28 days. third group given placebo...

Dog owners and veterinarians in small animal practices began to waive prevention of canine heartworm disease after infections seemed have disappeared Brazil. After 2013, infection rates rebounded, an evaluation the efficacy chemoprophylactic drugs became necessary. Included this re-evaluation was selamectin client-owned dogs residing a high infection-risk area. The preventive evaluated by topical application 24 at recommended rate (minimum 6 mg/kg) veterinarian monthly for 36 months. Blood...

Abstract Background Dirofilaria immitis is a life-threatening nematode spreading globally. Arsenical treatment currently recommended for removal of adult worms. However, arsenical not available in some countries, and there are dogs that cannot tolerate the rapid kill worms; therefore, alternative adulticide slow-kill treatments needed. Criticisms against use these protocols include potential allowing disease to progress development ML-resistant Methods The efficacy protocol includes...

Abstract Heartworm infection is a chronic disease with clinical signs and effects ranging from an asymptomatic condition to severe death. The prevalence of heartworm in the state Rio de Janeiro has been reported be high (21.3%). present study was conducted evaluate seroprevalence risk factors for canine population access veterinary services different areas Janeiro, Brazil. A total 1787 blood samples were obtained 135 practices across 8 (Rio municipality, São Gonçalo Niterói Baixada...

Serum amyloid A (SAA) is an acute phase protein whose concentration increases in inflammatory, infectious, and neoplastic conditions animals human beings. Multicentric lymphoma a common cancer dogs, chemotherapy indicated to attain long-term survival. However, frequent relapses lead changes chemotherapeutic protocols.The aims of this study were evaluate SAA as marker for relapse multicentric dogs determine whether induces the during treatment.SAA was measured by ELISA test healthy control...

Canine heartworm disease is a life-threatening caused by Dirofilaria immitis and prevalent in Brazil. The standard drug for its treatment, melarsomine dihydrochloride, fast-killing organic arsenical chemotherapeutic agent not approved Therefore, an alternative strategy, such as macrocyclic lactone combination with tetracycline antibiotic, has to be used. method long-term therapy that could lead compliance issues during treatment. aim of this case report present the efficacy safety off-label...

Abstract Giardia duodenalis is a zoonotic pathogen associated with gastrointestinal disease that has direct life cycle, cysts eliminated in the faeces of an infected host being ingested by susceptible host. In Brazil, studies chronically adult dogs estimated prevalence 10%–20%. Diagnosis giardiasis, as cause diarrhoea important for global One‐Health guidelines when controlling cyst dissemination environment. We investigated G. pet dog population metropolitan area Sao Paulo, compared efficacy...

Ceruloplasmina (Cp) é uma proteína positiva de fase aguda, responsável pelo transporte cobre e proteção das células tecidos contra compostos oxidantes. O objetivo deste estudo foi avaliar as concentrações Cp no momento do diagnóstico durante a quimioterapia em cães com linfoma multicêntrico (LM). mensurada utilizando-se técnica da orto dianisina dois grupos cães: dez sadios (controle) 13 LM. Todos os foram submetidos à quimioterapia. Cães sintomas doenças intercorrentes ou que haviam sido...

The aim of this study was to report the treatment efficacy generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed were treated sarolanerat a dose 2.0 mg/kg every 30 days. Sarolaner administered on days 0, 30, 60, and 90. analyzed as positive or negative for demodicosis. Clinical parameters recorded before after 90 On day 77.7% exhibited results skin scrapings, +60, 100% showed parasitological examination, which continued until 7.41% clinical remission, followed by...

Superficial bacterial folicullitis is a common dermatologic disease that caused mainly by Staphylococcus pseudintermedius, pathogen from the dog skin microbiota. We retrospectively evaluated 1,817 cases of dogs with superficial (primary or secondary) treated sodium cefovecin (8 mg/kg, SQ) every 14 days, according to clinical need. 68.5% required single dose (1,246/1,817); 28% animals (507/1.817) two doses and 3.5% (64/1.817) demanded three doses. Overall, responses were considered...

Canine atopic dermatitis gains worldwide attention due to its high incidence, and recent discoveries about complex pathophysiology. This study evaluated the effects of oclacitinib on pruritus scores 20 dogs with dermatitis. Levels described by owners were diagnosed based strict exclusion criteria, at 3 moments (days 0, 14 an 28), quantitative qualitative scales. In 85% dogs, oral administration 0.4 - 0.6 mg/kg twice daily resulted in more than 50% reduction level. The same dose once reduced...

The aim of this study was to report the treatment efficacy generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed were treated sarolanerat a dose 2.0 mg/kg every 30 days. Sarolaner administered on days 0, 30, 60, and 90. analyzed as positive or negative for demodicosis. Clinical parameters recorded before after 90 On day 77.7% exhibited results skin scrapings, +60, 100% showed parasitological examination, which continued until 7.41% clinical remission, followed by...