A5049121432- Chronic Disease Management Strategies
- Schizophrenia research and treatment
- Family Caregiving in Mental Illness
- Primary Care and Health Outcomes
- Atrial Fibrillation Management and Outcomes
- Emergency and Acute Care Studies
- Dementia and Cognitive Impairment Research
- Diabetes Management and Research
- Bipolar Disorder and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Health, psychology, and well-being
- Mental Health and Psychiatry
- Heart Failure Treatment and Management
- Traumatic Brain Injury Research
- Mental Health Treatment and Access
- Traumatic Brain Injury and Neurovascular Disturbances
- Electroconvulsive Therapy Studies
- Diabetes Management and Education
- Cardiac Health and Mental Health
- Acute Ischemic Stroke Management
- Treatment of Major Depression
- Geriatric Care and Nursing Homes
- Healthcare cost, quality, practices
- Intracerebral and Subarachnoid Hemorrhage Research
Aarhus University
2004-2021
Aarhus University Hospital
2020
University of Washington
2015
Persons with mental disorders are at a higher risk than the general population for subsequent development of certain medical conditions.
Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether dementia among people with comorbid DM is higher than sum of each exposure individually.To examine all-cause persons depression, DM, or both compared neither exposure.We performed a national population-based cohort study 454 532 adults, including 477 133 (19.4%) 223 174 (9.1%) 95 691 (3.9%) both. We included all living Danish citizens 50 years older who...
IMPORTANCEAlthough schizophrenia is associated with several age-related disorders and considerable cognitive impairment, it remains unclear whether the risk of dementia higher among persons compared those without schizophrenia.OBJECTIVE To determine in a large nationwide cohort study up to 18 years follow-up, taking age established factors for into account. DESIGN, SETTING, AND PARTICIPANTSThis population-based more than 2.8 million aged 50 or older used individual data from 6 registers...
Background and Purpose- It has been suggested that statins increase the risk of intracerebral hemorrhage in individuals with a history stroke, which led to precautionary principle avoiding patients prior hemorrhage. However, such prescribing reticence may be unfounded potentially harmful when considering well-established benefits statins. This study is so far largest explore statin-associated stroke. Methods- We conducted population-based, propensity score-matched cohort using information...
Persons with severe mental illness (SMI) have excess mortality, which may partly be explained by their high prevalence of diabetes.We compared the overall and cause-specific mortality in persons SMI diabetes that general Danish population between 1997 2009 linking data from national registries.The cohort counted 4 734 703 persons, during follow-up 651 080 died whom 1083 had diabetes. Compared background population, rate ratios (MRRs) for were 4.14 [95% confidence interval (CI) 3.81-4.51] men...
Hospitalizations for ambulatory care-sensitive conditions (ACSCs) and early rehospitalizations increase health care costs.To determine if individuals with serious mental illnesses (SMIs) (eg, schizophrenia or bipolar disorder) are at increased risk hospitalizations ACSCs, rehospitalization the same another ACSC, within 30 days.Population-based cohort study.A total of 5.9 million Danish persons aged 18 years older between January 1, 1999 December 31, 2013.The Psychiatric Central Register...
Background Depression is associated with an increased risk of a series cardiovascular diseases and symptom burden in patients atrial fibrillation. The aim this study was to determine the association between depression as well antidepressant treatment incident Design A nationwide register-based comparing fibrillation all Danes initiating from 2000 2013 ( N = 785,254) that 1:5-matched sample general population. Methods Cox regression used estimate adjusted hazard ratios (aHRs) 95% confidence...
Objective: Persons with severe mental illness die 15–20 years earlier on average than persons without illness. Although infection is one of the leading overall causes death, no studies have evaluated whether a higher mortality after those without. Method: The authors studied rate ratios and cumulative proportions an admission for compared by linking data from Danish national registries. Results: cohort consisted all hospitalized during period 1995–2011 in Denmark (N=806,835), whom 11,343 had...
Hospitalisations for ambulatory care-sensitive conditions (ACSCs), a group of chronic and acute illnesses considered not to require inpatient treatment if timely appropriate care is received, early rehospitalisations are common costly. We sought determine whether individuals with depression at increased risk hospitalisations ACSCs, rehospitalisation the same or another ACSC, within 30 days.National, population-based cohort study.Denmark.5,049,353 ≥ 18 years age between 1 January 2005 31...
<h3>Importance</h3> Individuals with bipolar disorder or schizophrenia have a higher risk of adverse outcomes from cardiovascular diseases. Oral anticoagulation therapy (OAT) for patients atrial fibrillation (AF) is needed stroke prevention, but whether face disparities in receiving this unknown. <h3>Objective</h3> To assess associated lower rate OAT initiation incident AF and prevalence those prevalent AF. <h3>Design, Setting, Participants</h3> A nationwide cohort study Danish was conducted...
Abstract Pain and depression are often associated suggesting that both conditions share a common neurobiological mechanism, which modulate emotional function processing of noxious information. thresholds hypothesized to be altered in depressed patients normalized with the amelioration depression. The purpose this study was therefore determine pain during after treatment electroconvulsive therapy (ECT) severe healthy controls. Seventeen (Hamilton score > 18) an age gender matched control...
Breast cancer is the leading cause of death in women worldwide. Nevertheless, it unknown whether higher mortality after breast contributes to life-expectancy gap 15 years with severe mental illness (SMI).We estimated all-cause rate ratios (MRRs) SMI, and both disorders compared neither disorder using data from nationwide registers Denmark for 1980-2012.The cohort included 2.7 million women, hereof 31,421 SMI (12,852 deaths), 104,342 (52,732 1,106 (656 deaths). Compared disorder, was 118%...
Background At time of discharge after a pneumonia admission, care planning for older persons with dementia is essential. However, limited by lack knowledge on the short-term prognosis. Aim To investigate 30-day mortality and readmission hospital in versus without dementia, to how these associations vary age, since discharge, medication use. Methods Using Danish registries, we investigated (+65 years) discharged 2000–2016 (N = 298,872). Adjusted rate ratios (aMRRs) incidence (aIRRs) were...
Background: Psychiatric disorders are associated with an increased risk for ambulatory care–sensitive condition (ACSC)-related hospitalizations, but it remains unknown whether this holds individuals nonsyndromic stress that is more prevalent in the general population. Objectives: To determine perceived ACSC-related hospitalizations and rehospitalizations, posthospitalization 30-day mortality. Research Design Measures: Population-based cohort study 118,410 participants from Danish National...
Background: Oral anticoagulation therapy (OAT) in patients with atrial fibrillation (AF) is a highly important preventive intervention, perhaps especially those comorbid depression, who have worse prognosis. However, OAT may pose particular challenges depressed patients. Objectives: To assess whether AF depression lower uptake. Methods: This nationwide register-based 2005–2016 cohort study of all Danes and indication (CHA 2 DS VASc stroke risk score ≥2) assessed initiation within 90 days...
Objectives Potentially inappropriate medications (PIMs) pose an increasing challenge in the ageing population. We aimed to assess extent of PIMs and prescriber-related variation PIM prevalence. Design Nationwide register-based cohort study. Setting General practice. Participants The 4.2 million adults listed with general practitioner (GP) clinics Denmark (n=1906) 2016. Main outcome measures estimated patients’ time by using 29 register-operationalised STOPP criteria linking GP redeemed...
Little is known about variations in the provision of chronic care services primary care.To describe frequency provided by GPs and analyse extent non-random variation service provision.Nationwide cohort study undertaken Denmark using data from 2016.Information on was obtained national health registers, including annual consultations, procedures, outreach home visits, talk therapy. The associations between provided, patient morbidity, socioeconomic factors were estimated. Service analysed,...
Depression is highly prevalent among hospitalized patients with pneumonia. At discharge, these transfer to a less care-intensive home-based setting. Nevertheless, little known on the prognosis in postdischarge period.The objective of this study was investigate influence depression 30-day mortality and readmission persons discharged after pneumonia admission.This population-based cohort using Danish registries.All aged 50+ years admission 2000-2016 Denmark.Mortality rate ratios for incidence...