A5103189456- Platelet Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Quinazolinone synthesis and applications
- Mast cells and histamine
- Renal Diseases and Glomerulopathies
- Inflammatory Bowel Disease
- Venous Thromboembolism Diagnosis and Management
- Spine and Intervertebral Disc Pathology
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Lung Cancer Diagnosis and Treatment
- Blood disorders and treatments
- Bone fractures and treatments
- Blood Coagulation and Thrombosis Mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood groups and transfusion
- Radiology practices and education
- Reconstructive Surgery and Microvascular Techniques
- CAR-T cell therapy research
- Radiation Dose and Imaging
- Blood properties and coagulation
- Spinal Fractures and Fixation Techniques
- Urticaria and Related Conditions
- Hip and Femur Fractures
Inserm
2000-2024
Université de Lorraine
2023-2024
Université de Strasbourg
2020-2021
Pakistan Army
2016
Institut Gustave Roussy
2000-2001
Centre National de la Recherche Scientifique
1998
Objective: Atherothrombosis occurs upon rupture of an atherosclerotic plaque and leads to the formation a mural thrombus. Computational fluid dynamics numerical models indicated that mechanical stress applied thrombus increases dramatically as grows, strong inter-platelet interactions are essential maintain its stability. We investigated whether GPVI (glycoprotein VI)-mediated platelet activation helps stability by using real-time video-microscopy. Approach Results: showed blockade with 2...
Abstract Aims Although the risk of thrombosis is well documented for inflammatory bowel disease [IBD] patients, underlying pathological mechanism seems to be different from other thrombotic conditions. Determining factors responsible increased in IBD would help improve management this frequent complication. Methods We studied interplay between platelets, coagulation, and von Willebrand factor [VWF] 193 patients experimental models [acute chronic] colitis wild-type VWF-deficient mice. Results...
Recent experimental data suggest that one of the major effects BCR-ABL gene expression in hematopoietic cells is inhibition apoptosis. Although exact mechanisms this phenomenon are not clear, it thought to be related fact induces several signalling pathways also activated by growth factors. In order determine anti-apoptotic role a cell line and by-pass influence cytokine-dependence, was expressed autonomously growing myelomonocytic U937 using retroviral vectors. There no resistance apoptosis...