A5040614520- Fungal and yeast genetics research
- Biofuel production and bioconversion
- Plant-Microbe Interactions and Immunity
- Microbial Natural Products and Biosynthesis
- Mycotoxins in Agriculture and Food
- Enzyme Production and Characterization
- Brucella: diagnosis, epidemiology, treatment
- Plant Pathogens and Fungal Diseases
- Monoclonal and Polyclonal Antibodies Research
- Insect Resistance and Genetics
- Mycorrhizal Fungi and Plant Interactions
- Radioactive element chemistry and processing
- Analytical chemistry methods development
- Transgenic Plants and Applications
- Glycosylation and Glycoproteins Research
- Biochemical and Structural Characterization
- Bacteriophages and microbial interactions
- Protist diversity and phylogeny
- Entomopathogenic Microorganisms in Pest Control
- Extraction and Separation Processes
- Enzyme-mediated dye degradation
- Genomics and Phylogenetic Studies
- Escherichia coli research studies
- RNA and protein synthesis mechanisms
- Fungal Biology and Applications
University of Göttingen
2018
Amirkabir University of Technology
2016
TU Wien
2012-2015
Chalmers University of Technology
2015
Trichoderma reesei is an industrial producer of enzymes that degrade lignocellulosic polysaccharides to soluble monomers, which can be fermented biofuels. Here we show the expression genes for lignocellulose degradation are controlled by orthologous T. protein methyltransferase LAE1. In a lae1 deletion mutant observed complete loss all seven cellulases, auxiliary factors cellulose degradation, β-glucosidases and xylanases were no longer expressed. Conversely, enhanced resulted in...
Abstract The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi, and it can modify heterochromatin structure Aspergillus nidulans. We have recently shown ortholog Trichoderma reesei (LAE1), fungus an industrial producer cellulase hemicellulase enzymes, regulates cellulases polysaccharide hydrolases. To learn more about function LAE1 T. reesei, we assessed effect deletion overexpression lae1 on...
Trichoderma reesei is the industrial producer of cellulases and hemicellulases for biorefinery processes. Their expression obligatorily dependent on function protein methyltransferase LAE1. The Aspergillus nidulans orthologue LAE1 - LaeA part VELVET complex consisting LaeA, VeA VelB that regulates secondary metabolism sexual as well asexual reproduction. Here we have therefore investigated VEL1, T. A. VeA. Deletion vel1 locus causes a complete light-independent loss conidiation, impairs...
The extraction efficiency of hexavalent chromium, Cr(VI), from water has been investigated using a vegetable oil based emulsion liquid membrane (ELM) technique. main purpose this study was to create novel ELM formulation by choosing more environmentally friendly and non-toxic diluent such as palm oil. phase so formulated includes the mobile carrier tri-n-octylmethylammonium chloride (TOMAC), facilitate metal transport, hydrophilic surfactant Tween 80 dispersion in aqueous solution. Span is...
Abstract The most common sequences of peptaibiotics are 11‐residue peptaibols found widely distributed in the genus Trichoderma / Hypocrea. Frequently associated 14‐residue sharing partial sequence identity. Genome sequencing projects three strains major clades reveal presence up to types nonribosomal peptide synthetases with 7, 14, or 18–20 amino acid‐adding modules. Here, we provide evidence that 14‐module NRPS type T. virens, reesei (teleomorph Hypocrea jecorina ), and atroviride produces...
In Ascomycota the protein methyltransferase LaeA is a global regulator that affects expression of secondary metabolite gene clusters, and controls sexual asexual development. The common mycoparasitic fungus Trichoderma atroviride one most widely studied agents biological control plant-pathogenic fungi also serves as model for research on regulation sporulation (conidiation) by environmental stimuli such light and/or mechanical injury. order to learn possible involvement LAE1 in these two...
The NF-κB-like velvet domain protein VosA (viability of spores) binds to more than 1,500 promoter sequences in the filamentous fungus Aspergillus nidulans. inhibits premature induction developmental activator gene brlA, which promotes asexual spore formation response environmental cues as light. represses a novel genetic network controlled by sclB gene. SclB function is antagonistic VosA, because it induces expression early genes differentiation flbC and flbD well brlA. development...
The filamentous fungus Trichoderma parareesei is the asexually reproducing ancestor of reesei, holomorphic industrial producer cellulase and hemicellulase. Here, we present genome sequence T. type strain CBS 125925, which contains genes for 9,318 proteins.
The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi. In Trichoderma reesei, its ortholog LAE1 appears to predominantly regulate genes involved increasing competitive fitness environment, including cellulases and polysaccharide hydrolases. A drawback all studies related LaeA/LAE1 function so far, however, respective loss-of-function overexpressing mutants display different growth rates. Thus some...