A5101554998- Immune Response and Inflammation
- Bioactive Compounds and Antitumor Agents
- Antimicrobial Peptides and Activities
- Parasite Biology and Host Interactions
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Cell Function and Interaction
- Systemic Lupus Erythematosus Research
- Animal Disease Management and Epidemiology
- Carcinogens and Genotoxicity Assessment
- Milk Quality and Mastitis in Dairy Cows
- Cancer-related molecular mechanisms research
- Flavonoids in Medical Research
- Helminth infection and control
- Cancer Mechanisms and Therapy
- Dengue and Mosquito Control Research
- NF-κB Signaling Pathways
- Effects and risks of endocrine disrupting chemicals
- T-cell and B-cell Immunology
- Genetically Modified Organisms Research
- Research on Leishmaniasis Studies
- Crustacean biology and ecology
- Immune cells in cancer
- MicroRNA in disease regulation
- Animal Diversity and Health Studies
- Trypanosoma species research and implications
Kunming Medical University
2007-2025
Weifang Medical University
2013-2021
Baoshan College
2021
Griffith University
2019-2020
Union Hospital
2013
Wuhan University
2013
Renmin Hospital of Wuhan University
2013
Huazhong University of Science and Technology
2013
Sichuan University
2013
Objective Systemic lupus erythematosus (SLE) is an autoimmune disease with complex etiology that not yet entirely understood. We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE a Tibetan population. Methods Peripheral blood mononuclear cells from patients (n = 5) healthy controls were used for miRNA–mRNA co-sequencing detect miRNAs related immune abnormalities associated SLE. Luciferase reporter assay was identify targets candidate miRNA. The target...
Abstract Background Leishmania species belong to the family Trypanosomatidae and cause leishmaniasis, a geographically widespread disease that infects humans other vertebrates. This remains endemic in China. Due large geographic area complex ecological environment, taxonomic position phylogenetic relationship of Chinese isolates remain uncertain. A recent internal transcribed spacer 1 cytochrome oxidase II phylogeny has challenged some aspects their traditional taxonomy as well cladistics...
Host defense caerin 1.1 and 1.9 peptides, isolated from the glandular secretion of Australian tree frogs, genus Litoria, have been previously shown to multiple biological activities, including inhibition human papillomavirus (HPV) 16 early protein E7 transformed murine as well cancerous cell proliferation both in vitro vivo. However, mechanism underlying their anti-proliferative activities against HPV18+ cervical cancer HeLa cells remains unknown. This study comparatively investigated...
Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune‐mediated inflammation affecting multiple organs and systems. The aim of this study was to establish validate a pristane‐induced SLE model in C57BL/6J mice analyze immune cell alterations. Methods Six‐week‐old female were randomly assigned two groups ( n = 6 per group). pristane group received single 0.5 mL intraperitoneal injection pristane, whereas the control saline. Urine samples...
Abstract Background Bisphenol A is widely used in the manufacture of polycarbonate plastics and has caused increasing concern over its potential adverse impacts on spermatogenesis. However, effect bisphenol spermiogenesis yet to be explored. Objectives To evaluate whether effects DNA integrity protamination spermatogenic cell. Materials methods Newborn male mice were subcutaneously injected with (0.1, 5 mg/kg body weight, n = 15) or coin oil (control group, 20) daily from post‐natal day 1...
Excessive activation of immune cells plays a key role in the pathogenesis systemic lupus erythematosus (SLE). The regulation by miRNAs is research hotspot. In this study, second-generation high-throughput sequencing revealed reduction miR-99a-3p expression patients with SLE; however, specific mechanism underlying phenomenon remains unclear. After transfection an agomir, proliferation Ball-1 decreased and levels their apoptosis increased. opposite effects were observed transfected antagomir....
Abstract For a long time, there is no clear-cut to identify some species of paragonimus in Yunnan Province, China. This paper involved the distribution Paragonimus Jinping country and Baoshan city, province. In this experiment, metacercariae, excysted eggs, adult worms were obtained from different hosts observed measured. Cats have been described as appropriate definitive host sp., which are closed P. cheni according morphology. Especially ovaries few has third branches. With SEM...