A5060408728- Neurogenesis and neuroplasticity mechanisms
- Silymarin and Mushroom Poisoning
- Analytical Chemistry and Chromatography
- Neuroinflammation and Neurodegeneration Mechanisms
- Asymmetric Hydrogenation and Catalysis
- Synthesis and Catalytic Reactions
- Memory and Neural Mechanisms
- Catalytic C–H Functionalization Methods
- Crystallization and Solubility Studies
- Pharmacological Effects of Natural Compounds
- Advancements in Transdermal Drug Delivery
- Neonatal and fetal brain pathology
- Lipid Membrane Structure and Behavior
- Regulation of Appetite and Obesity
Central South University
2022-2023
Matrine (MAR), oxymatrine (OMAR), and sophoridine (SPD) are natural alkaloids with varying biological activities; matrine was recently used for the treatment of coronavirus disease 2019 (COVID-19). However, short half-lives rapid elimination these matrine-type would lead to low oral bioavailability serious side effects. Herein, resveratrol (RES) selected as a co-former prepare their co-amorphous systems improve therapeutic index. The formation MAR-RES, OMAR-RES, SPD-RES established through...
Abstract A cohort of morphologically heterogenous doublecortin immunoreactive (DCX+) “immature neurons” has been identified in the cerebral cortex largely around layer II and amygdala paralaminar nucleus (PLN) among various mammals. To gain a wide spatiotemporal view on these neurons humans, we examined amygdalar DCX + brains infants to 100 year-old individuals. Layer occurred throughout cerebrum infants/toddlers, mainly temporal lobe adolescents adults, only surrounding elderly. Amygdalar...