A5064034003- Advanced Drug Delivery Systems
- Inhalation and Respiratory Drug Delivery
- Cystic Fibrosis Research Advances
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Microencapsulation and Drying Processes
- Drug Solubulity and Delivery Systems
- Fatty Acid Research and Health
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Proteins in Food Systems
University of the Basque Country
2014-2020
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2014-2019
Oxidative damage has been linked to a number of diseases. Oleuropein (OLE), natural occurring polyphenol from olive leaves (Olea europaea L.), is known be potent antioxidant compound with inherent instability and compromised bioavailability. Therefore, in this work, nanostructured lipid carriers (NLCs) were proposed for OLE encapsulation protect improve its efficacy. The matrix, composed oil Precirol, was optimized prior encapsulation. characterization the oleuropein-loaded NLCs (NLC-OLE)...
In the last decades, encapsulation of antibiotics into nanoparticulate carriers has gained increasing attention for treatment infectious diseases. Sodium colistimethate-loaded solid lipid nanoparticles (Colist-SLNs) and nanostructured (Colist-NLCs) were designed aiming to treat pulmonary infection associated cystic fibrosis patients. The freeze-dried using trehalose as cryoprotectant. stability both was analysed over one year according International Conference Harmonisation (ICH) guidelines...