A5048333149- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Fatty Acid Research and Health
- Trypanosoma species research and implications
- Cystic Fibrosis Research Advances
- Wound Healing and Treatments
- Inhalation and Respiratory Drug Delivery
- Antibiotic Use and Resistance
- Advanced Drug Delivery Systems
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Pluripotent Stem Cells Research
- Synthesis and Biological Evaluation
- biodegradable polymer synthesis and properties
- Acute Lymphoblastic Leukemia research
- Pressure Ulcer Prevention and Management
- Advancements in Transdermal Drug Delivery
- Historical and socio-economic studies of Spain and related regions
- Nuclear Receptors and Signaling
- Edible Oils Quality and Analysis
- Antimicrobial agents and applications
- Chromosomal and Genetic Variations
- Single-cell and spatial transcriptomics
- Research on Leishmaniasis Studies
- Archaeological and Historical Studies
Instituto de Investigación Biomédica de Salamanca
2024
Centro de Investigación Biomédica en Red de Cáncer
2024
Zigong First People's Hospital
2020
Ikerlan
2020
Oxidative damage has been linked to a number of diseases. Oleuropein (OLE), natural occurring polyphenol from olive leaves (Olea europaea L.), is known be potent antioxidant compound with inherent instability and compromised bioavailability. Therefore, in this work, nanostructured lipid carriers (NLCs) were proposed for OLE encapsulation protect improve its efficacy. The matrix, composed oil Precirol, was optimized prior encapsulation. characterization the oleuropein-loaded NLCs (NLC-OLE)...
Cystic fibrosis (CF) is the main genetic cause of death among Caucasian population. The disease characterized by abnormal fluid and electrolyte mobility across secretory epithelia. first manifestations occur within hours birth (meconium ileus), later extending to other organs, generally affecting respiratory tract. It caused mutations in cystic transmembrane conductance regulator (CFTR) gene. CFTR encodes a cyclic adenosine monophosphate (cAMP)-dependent, phosphorylation-regulated chloride...
Clonal dissemination of multidrug-resistant Pseudomonas aeruginosa (MDRPA) is a major concern worldwide. The aim this study was to explore the mechanisms leading carbapenem resistance an MDRPA clone. Isolates were obtained from surgical wound, sputum, urine and blood culture. Pulsed-field gel electrophoresis (PFGE) showed high genomic homogeneity these isolates confirmed circulation endemic clone belonging serotype O4. Outer membrane protein (OMP) bands visualized by SDS-PAGE, meropenem...
One of the current greatest challenges Chagas disease is establishment biomarkers to assess efficacy drugs in a short period time. In this context, reactivity sera from 66 adults with chronic indeterminate (IND) for set four Trypanosoma cruzi antigens (KMP11, PFR2, HSP70, and 3973d) was analyzed before after benznidazole treatment. The results showed that against these decreased at 9, 24, 48 months Moreover, 42.4% 68.75% IND patients met established standard criteria therapeutic (STEC) 24...
Wound healing is a complex process that can be severely impaired due to pathological situations such as diabetes mellitus. Diabetic foot ulcers are common complication of this pathology and characterized by an excessive inflammatory response. In work, the effects local treatment with recombinant human epidermal growth factor (rhEGF) were studied using full-thickness wound model in streptozotocin-induced diabetic rats. was assessed different concentrations rhEGF (0.1, 0.5, 2.0 8.0 µg/mL),...
An alternative HPLC approach for oleuropein determination in olive oil, <italic>Olea europaea</italic> leaf extracts and nanoparticles with minimized environmental impact.
The mutation E280A in PSEN1 (presenilin-1) is the most common cause of early-onset familial Alzheimer's Disease (fAD). It presents autosomal dominant inheritance and frequently leads to manifestation disease relatively young individuals. Here we report generation one iPSC line derived from an patient. OriP/EBNA1-based episomal plasmids containing OCT3/4, SOX2, KLF4, L-MYC, LIN28, BCL-xL shp53 were used reprogram oral mucosa fibroblasts. generated has normal karyotype, carry mutation, free...