A5051889205- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Reconstructive Surgery and Microvascular Techniques
- COVID-19 and healthcare impacts
- Bone fractures and treatments
- Advanced Neuroimaging Techniques and Applications
- Surgical site infection prevention
- Congenital limb and hand anomalies
- Elbow and Forearm Trauma Treatment
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder and Clavicle Injuries
- Sarcoma Diagnosis and Treatment
- Spinal Cord Injury Research
- Shoulder Injury and Treatment
- Trauma Management and Diagnosis
- Vascular Procedures and Complications
- Organ and Tissue Transplantation Research
- Orthopedic Infections and Treatments
- Genomic variations and chromosomal abnormalities
- Nerve injury and regeneration
- Wound Healing and Treatments
- Pain Management and Treatment
- Soft tissue tumor case studies
Leeds Teaching Hospitals NHS Trust
2014-2025
Leeds General Infirmary
2012-2025
University of Leeds
2017-2025
Oxford University Hospitals NHS Trust
2025
University of Oxford
2025
John Radcliffe Hospital
2025
Bristol Royal Infirmary
2024
Sunderland Royal Hospital
2024
Stoke Mandeville Hospital
2024
University Hospital of Wales
2024
Traumatic brachial plexus injuries (TBPI) are often devastating and life-changing thought to be becoming more prevalent. Several studies have investigated the epidemiology of TBPI in other countries (e.g., United States, Brazil); however, a similar analysis is yet undertaken England Wales. The aim this cohort study was determine incidence Trauma Audit Research Network database reviewed identify 1,297 eligible patients admitted with between 1990 2022. Patient demographics, injury mechanism,...
To date, three unilateral and seven bilateral hand upper limb transplants have been performed by the UK Hand Transplant Programme. We report functional outcomes for our first six patients, who followed between 4 10 years. All patients gained protective sensation to pain, pressure temperature, a recordable power grip. saw an improvement in Canadian Occupational Performance Measure performance satisfaction scores, with five out of improving Disability Arm Shoulder scores. The Score System...
Predicting prognosis after nerve injury and compression can be challenging, even for the experienced clinician. Although thorough clinical assessment aid diagnosis, we cannot always precise about long-term functional recovery of either motor or sensory nerves. To evaluate severity injury, surgical exploration remains gold standard, particularly iatrogenic major from trauma, such as brachial plexus injury. Recently, advances in imaging techniques (ultrasound, magnetic resonance [MRI] MR...
Introduction GABA (γ-aminobutyric acid) is the major inhibitory neurotransmitter in brain. In response to injury within central nervous system, promotes cortical plasticity and represents a potential pharmacological target improve functional recovery. However, it unclear how changes brain after traumatic brachial plexus injuries (tBPIs) which rationale for this pilot study. Methods We serially scanned seven males (mean age 42 years [SD 19] without head injury) up 19 months tBPIs. T1-weighted...
The Impact of Hand Nerve Disorders scale is a patient-reported outcome measure for upper limb nerve pathology. We aimed to assess its structural validity using item response theory and develop computerized adaptive testing algorithms. conducted series psychometric studies constructs measured, applied an model the data, then developed results showed two distinct factors: ‘Motor Function’ ‘Pain’. separate tests which reduced number questions from six (‘Pain’) 16 (‘Motor Function’) median three...
Root avulsion in patients with traumatic brachial plexus injury (tBPI) are common and MRI is used to help identify who need urgent reconstruction. Diffusion tensor (DTI) generates proxy measures of nerve 'health' which sensitive myelination, axon diameter, fibre density organisation. This prospective multicentre pilot study assessed the utility DTI for detecting root adults acute injury. Patients underwent at 3 Tesla. Fractional anisotropy (FA) radial diffusivity (RD) were extracted from...
In the United Kingdom [UK], Advanced Clinical Practice (ACP) roles are being developed to improve access high-quality patient care, where healthcare services struggling meet steadily increasing service demands. Increasingly, ACP hand therapists assessing and treating acute closed fractures. However, knowledge skills required of these has not been identified or standardised. Consensus recommendations were from an expert panel medical doctors using electronic Delphi process. Participants...
Identification of root avulsions is critical importance in traumatic brachial plexus injuries because it alters the reconstruction and prognosis. Pre-operative magnetic resonance imaging gaining popularity, but there limited conflicting data on its diagnostic accuracy for avulsion. This cohort study describes consecutive patients requiring exploration following trauma between 2008 2016. The index test was at 1.5 Tesla reference operative supraclavicular plexus. Complete from 29 males...
Cross-sectional MRI has modest diagnostic accuracy for diagnosing traumatic brachial plexus root avulsions. Consequently, patients either undergo major exploratory surgery or months of surveillance to determine if and what nerve reconstruction is needed. This study aimed develop a diffusion tensor imaging (DTI) protocol at 3 Tesla visualise normal roots identify avulsions the plexus. Seven healthy adults twelve with known (operatively explored) unilateral were scanned. DTI was acquired using...
Abstract Cubital tunnel syndrome (CuTS) is the 2nd most common compressive neuropathy. To improve both diagnosis and selection of patients for surgery, there a pressing need to develop reliable objective test ulnar nerve ‘health’. Diffusion tensor imaging (DTI) characterises tissue microstructure may identify differences in normal from those affected by CuTS. The aim this study was compare DTI metrics nerves healthy (asymptomatic) adults with CuTS awaiting surgery. acquired at 3.0 T using...
The aims of this study were to describe the epidemiology metacarpal shaft fractures (MSFs), assess variation in treatment and complications following standard care, document hospital resource use, explore factors associated with modality.
This study aimed to analyse and contrast changes in health-related quality of life (HR-QoL) hand symptoms the first 6 months after surgical treatment for primary cubital tunnel syndrome. Data originated from United Kingdom Hand Registry. HR-QoL was assessed using generic EuroQol five-dimensional assessment tool (EQ-5D-5L) Patient Evaluation Measure (PEM). In total, 281 patients were included statistical analysis. Cubital release resulted clinically relevant relief symptoms. However, no...