A5025896778- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Congenital limb and hand anomalies
- Nerve injury and regeneration
- Peripheral Nerve Disorders
- Nerve Injury and Rehabilitation
- Bone fractures and treatments
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Tendon Structure and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- Dupuytren's Contracture and Treatments
- Musculoskeletal pain and rehabilitation
- Shoulder Injury and Treatment
- Surgical Sutures and Adhesives
- Neuroscience and Neural Engineering
- Pain Mechanisms and Treatments
- Muscle activation and electromyography studies
- Transcranial Magnetic Stimulation Studies
- Surgical Simulation and Training
- Surgical site infection prevention
- Anatomy and Medical Technology
- Organ and Tissue Transplantation Research
Radboud University Nijmegen
2015-2025
Radboud University Medical Center
2015-2025
Radboud Institute for Molecular Life Sciences
2022-2025
Erasmus University Rotterdam
2010-2023
Erasmus MC
2011-2023
Center For Reconstructive Urethral Surgery
2011-2022
Jeroen Bosch Ziekenhuis
2022
Marymount University
2021-2022
University Medical Center
2014-2021
University Hospital and Clinics
2021
Injuries to the hand and wrist account for approximately 20% of patient visits emergency departments may impose a large economic burden. The purpose this study was estimate total health-care costs productivity injuries compare them with other important injury groups in nationwide study.Data were retrieved from Dutch Injury Surveillance System, National Hospital Discharge Registry, follow-up survey conducted between 2007 2008. incidence, costs, (due absenteeism) calculated by age group, sex,...
Keloid scars may be painful, itch severely and cosmetically disturbing. The burden of keloid disease, however, has not yet been determined. This study evaluated the association disease with health-related quality life (HRQL) identified indicators using a cross-sectional survey study, one disease-specific HRQL measure (Skindex-29) 2 generic measures (SF-36 EQ-5D-5L). A total 106 patients no other skin diseases participated in study. Having was associated considerable impairment emotional...
Monoscopically projected three-dimensional (3D) visualization technology may have significant disadvantages for students with lower visual-spatial abilities despite its overall effectiveness in teaching anatomy. Previous research suggests that stereopsis facilitate a better comprehension of anatomical knowledge. This study evaluated the educational stereoscopic augmented reality (AR) and modifying effect on learning. In double-center randomized controlled trial, first- second-year...
To describe the principles, process, and results of creating International Consortium for Health Outcomes Measurement (ICHOM) standard set hand wrist conditions.Following standardized methods ICHOM, an international working group surgeons, therapists, researchers was assembled to develop evidence-based, patient-centered, outcome measures patients with conditions. Multiple systematic reviews were performed support our choices domains tools Fourteen video conferences held between March 2018...
Objective: Topical negative pressure (TNP) (vacuum therapy) is frequently used in the management of acute, traumatic, infected and chronic full-thickness wounds. This prospective clinical randomised trial compared costs TNP with conventional therapy (moist gauze) wounds that required surgical closure. Method: The direct medical total number resources needed to achieve a healthy, granulating wound bed was ‘ready for therapy’ were calculated. Results: Fifty-four patients admitted department...
The clinical effects of topical negative pressure therapy (TNP) on wound healing are well described in numerous articles. While the mechanism(s) action not completely understood, it is postulated that reduction local and interstitial tissue edema, increased perfusion (peri-) area, changed bacterial composition, mechanical stimulation woundbed contribute to success. Our hypothesis with removal excessive fluid, proteolytic enzymes negatively influencing process removed. aim was assess whether...
Vascularization is still one of the most important limitations for survival engineered tissues after implantation. In this study, we aim to improve in vivo vascularization adipose tissue by preforming vascular structures within vitro-engineered constructs that can integrate with host system upon Different cell culture media were tested and different amounts human tissue-derived mesenchymal stromal cells (ASC) umbilical vein endothelial (HUVEC) combined spheroid cocultures obtain optimal...
This study was designed to evaluate correlations between the hand injury severity scoring system (HISS) and measures of impairment disability obtained 6 months after a injury. A statistically significant positive correlation found residual impairment, as measured with American Medical Association's (AMA) "Guides evaluation permanent 4th edition". No Disabilities Arm, Shoulder Hand (DASH) questionnaire, which from patient's perspective. There however AMA total body results DASH questionnaire....
Background: Saethre-Chotzen syndrome is a craniosynostosis further characterized by distinctive facial and limb abnormalities. It shows complete penetrance variable expressivity has been linked to the TWIST gene on chromosome 7p21; more than 80 different intragenic mutations and, recently, large deletions have detected in patients. The aim of this study was genetically phenotypically characterize patients with clinical diagnosis syndrome. Methods: Patients as well those genetic (n = 34) were...
Wound healing in diabetes is frequently impaired, and its treatment remains a challenge. We tested therapeutic strategy of potentiating intrinsic tissue regeneration by restoring the wound cellular environment using heparan sulfate glycosaminoglycan mimetic, OTR4120. The effect OTR4120 on diabetic ulcers was investigated. Experimental induced intraperitoneal injection streptozotocin. Seven weeks after induction diabetes, rats were ulcerated clamping pair magnet disks dorsal skin for 16 h....
Microsurgeons suspect that cigarette smoking reduces the survival of free vascularized flaps and replantations, but this has never been proven. This experimental study investigates effect on free-flap survival. A fasciocutaneous epigastric flap was used in 30 rats as a pedicled flap. Of each group, 10 were smoked 6 weeks before 2 after surgery, only underwent sham procedure. Also, distally based dorsal skin cut all rats, representing random Vitality size both patency vascular anastomoses...
The aim of this study was to assess long-term results extensor indicis (EI) pollicis longus (EPL) transfers and donor site morbidity. A specific EI-EPL evaluation method (SEEM) used measure EPL function after transfer. outcomes in 17 patients are presented. Results were assessed by the Geldmacher score, SEEM, mobility strength thumb index finger, pinch grip strength, a questionnaire, comparing operated non-operated hands. Based on excellent good 11 patients. There no marked loss independent...
A multicenter, multinational, blinded, randomized, parallel-group, phase II study was conducted to investigate the use of recombinant human tissue factor pathway inhibitor (rhTFPI; SC-59735) as an antithrombotic additive intraluminal irrigating solution during microvascular anastomosis in free flap reconstructive surgery. total 622 patients undergoing reconstruction were randomly assigned three groups. For each group, a different administered at completion arterial and venous anastomoses...