The aim of this study was to compare the prevalence human papillomavirus (HPV) infection in laryngeal squamous cell carcinoma using two methods: PCR-DNA enzyme immunoassay (PCR/DEIA) and immunohistochemistry (IHC) for detection HPV specimens correlate presence with epidemiological clinicopathological features recurrence survival. DNA amplified from 93 paraffin-embedded tissue by short PCR fragment (SPF 10) primer set PCR/DNA method. monoclonal anti-human papilloma virus antibodies Clone K1H8...

Nasopharyngeal angiofibroma (NA) is a rare, vascular tumor affecting adolescent males. Due to aggressive local growth, skull base location and risk of profound hemorrhage, NA challenge for surgeons. Angiofibromas have been sporadically described in extanasopharyngeal locations. We review ten cases extranasopharyngeal (ENA) discuss the incidence, clinical presentation management this pathology. The group consisted 4 males 5 females aged 8-49. There were 7 patients with nasal angiofibroma, 1...

The number of cancers is constantly increasing. An important role in the etiology many them played by viral factor, oncogenic viruses, such as Human Papillomavirus. article shows current epidemiological situation and describes structure virus modes transmission. It also explains HPV infection cancer with particular emphasis on oropharynx head neck cancer. Summarizing, plays an carcinogenesis tumors. presence genetic material tumor may influence prognosis treatment method choices.

The aim of the study was to evaluate and compare various helical CT display modes [virtual endoscopy (VE)] multiplanar reformations (MPR), conventional flexible tracheobronchoscopy (FT) intra-operative (IO) findings in patients with tracheal stenosis analyze advantage MPR VE diagnosis treatment planning postoperative follow-up. Thirty-seven underwent standard neck chest followed by VE. Results were correlated results FT IO findings. Thirty-three 37 stenoses correctly graded measured...

The aim of the study was to determine prevalence and genotypes HPV infection in laryngeal cancer specimens, normal mucosa obtained from surgical margin nodules using a novel high sensitive specific SPF10 DNA test, PCR/DEIA method INNO-LiPA genotyping assay. correlation between presence clinico-pathological features analyzed. Tissue samples were collected 93 primary squamous cell carcinoma (LSCC), 49 specimens 22 serving as control group. amplified by short PCR fragment (SPF10) primer set...

The aim of this study was to analyze the prevalence HPV and EBV in oral oropharyngeal squamous cell carcinoma south-eastern Poland. correlation between viral infection, OSCC, alcohol use, tobacco smoking, demographic data (gender, age, place residence), anatomic location, pre-treatment staging, evidence metastases lymph nodes, grading also investigated. examination samples were collected from paraffin tissue blocks, 154 patients. Viral DNA amplified by nested-PCR method. detected 29.2 %...

Phase angle could be an alternative to subjective global assessment for the of nutrition status in patients with head-and-neck cancer.We prospectively evaluated a cohort 75 stage iiib and iv treated at Otolaryngology Department, Head Neck Surgery, Medical University Lublin, Poland. Bioelectrical impedance analysis was performed all using analyzer that operated 50 kHz. The phase calculated as reactance divided by resistance (Xc/R) expressed degrees. Kaplan-Meier method used calculate...

The high incidence of, and mortality from, head neck cancers (HNCs), including those related to Epstein-Barr virus (EBV), constitute a major challenge for modern medicine, both in terms of diagnosis treatment. Therefore, many researchers have made efforts identify diagnostic prognostic factors. aim this study was evaluate the usefulness matrix metalloproteinase 3 (MMP 3) 9 9) EBV positive oropharyngeal squamous cell carcinoma (OPSCC) patients. For purpose, level these MMPs serum patients...

Background: The role of the Epstein–Barr virus (EBV), first known human oncogenic virus, in development nasopharyngeal cancer (NPC) is already well documented. There are few studies available scientific literature on oropharyngeal associated with EBV infection. Due to lack an effective vaccine against EBV, it necessary search for new markers early diagnosis and prognosis this disease. aim current study was determine usefulness anti-Zta anti-LMP1 antibodies as diagnostic prognostic positive...

Objective: To assess whether the incidence of complications stapes surgery depended on sequence surgical steps and CO2 laser use in surgery. Study Design Setting: Retrospective prospective analysis 420 consecutive stapedotomies was set tertiary referral University Hospital. Patients: 376 patients with otosclerosis whom primary were performed. Intervention: Stapedotomy under local anesthesia using manual perforators laser. Main Outcome Measure: The incus subluxation, floating footplate during...

Evaluation of prognostic value capacitance membrane (Cm), parameter measured by bioelectrical impedance (BIA) as an alternative to known clinical factors in patients with Head and Neck Cancer (HNC).A cohort 75 stage IIIB IV HNC treated Department Otolaryngology, Surgery, Medical University Lublin, Poland were prospectively evaluated. Cm measurements performed all using a analyzer that was set on frequency 50 kHz. Results presented nF. Survival differences estimated Kaplan-Meier...

The aim of this study was to analyze the prevalence BK virus, Human Papillomavirus and Epstein-Barr virus in oropharyngeal cancer, test our hypothesis that BKV/HPV/EBV co-infection plays a role squamous cell carcinoma. correlation between viral infection, OSCC, anatomic location, pre-treatment staging, evidence metastases lymph nodes, grading also investigated. examination samples were collected from 62 patients paraffin tissue blocks. Males (90.3%) with, smoking (83.9%) alcohol abuse...

The ratio of extracellular mass to body cell (ecm/bcm), determined by bioelectrical impedance analysis, has been found be a potentially useful indicator nutrition status. Subjective global assessment (sga) is subjective method evaluating status in head-and-neck cancer. present study was conducted investigate the association between ecm/bcm and sga cancer.Patients were classified as either well-nourished or malnourished sga. Bioelectrical analysis on population 75 patients with histologically...

Conclusion. Contrary to most reports, our study shows that the expression of cyclin D1 is not an independent prognostic factor in patients with laryngeal cancer (LC). No correlation between and survival rates LC was found a multivariate analysis. Objectives. The aim this determine possible relevance protein as criteria analyse clinicopathological features rates. Materials methods. Immunohistochemistry staining used detect 130 samples 22 specimens nodules. Results. Cyclin 52 (40%) 3 (13.6%)...

Head and neck cancers are the most common worldwide. It is estimated that approximately 90% of all head represented by squamous cell carcinoma (SCC). There many risk factors causing this type cancer, including environmental lifestyle choices, such as tobacco smoking or abusing alcohol. Other important factor include infectious factors.The aim study was to analyze prevalence BK JC virus infections among patients with oral (OSCC).The correlation between BKV infection OSCC, BKV, alcohol abuse,...

The use of formalin-fixed paraffin-embedded (FFPE) tissues for HPV DNA detection by PCR from biopsy materials is not entirely clear in retrospective studies. aim our study was to evaluate the usefulness and efficiency FFPE laryngeal cancer (LSCC) immunohistochemistry reaction (IHC) PCR-DNA enzyme immunoassay method (PCR/DEIA) compare with DFT. HPV-DNA amplified 54 LSCC specimens short fragment (SPF10) primer set using PCR/DNA monoclonal anti Human Papillomavirus antibodies IHC. In same...

Abstract Background The purpose of this study was to investigate tissue electrical properties in patients with head and neck cancer. Methods In the cross‐sectional direct bioimpedance measures (resistance, reactance, phase angle) determined by bioelectrical impedance analysis (BIA) were performed on 31 cancer healthy volunteers matched age sex as a control group. Results Phase angle at 50 kHz found be significantly lower ( p = .000006) than group (4.69° ± 0.71 vs 5.59° 0.70, respectively)....

One of the risks in middle ear surgery is high frequency hearing loss. It believed that manipulations on ossicles with instruments may cause overstimulation inner and damage hear cells. Controversy arises whether temporary separation has any impact transfer function threshold after surgery. The aim study to evaluate influence incudostapedial joint (ISJ) an experimental model.With use single point laser Doppler vibrometer (LDV) stapes velocity intact chain ISJ was measured 5 fresh human...

Direct bioimpedance measures [resistance, reactance, phase angle] determined by bioelectrical impedance analysis (BIA) detect changes in tissue electrical properties. Bioelectrical vector (BIVA) technique is a promising tool, using the pure data obtained BIA evaluation for screening and monitoring of nutrition hydration status. BIVA has potential to be used as routine method clinical setting assessment management body fluids. The study was conducted evaluate soft mass through pattern plots...

<b>Context:</b> Bioelectrical impedance analysis (BIA) detects changes in tissue electrical properties and has been seen as a prognostic tool several chronic conditions, including cancer. AIMS: The study was conducted to investigate whether there are any differences patients with head neck cancer (H NC) before after surgery treatment. <b>Settings Design:</b> observational performed at the Otolaryngology Department, Head Neck Oncology. <b>Materials Methods</b> : Tissue were assessed 31 H NC 2...