A5044608168- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Drug Solubulity and Delivery Systems
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Pediatric health and respiratory diseases
- Nutrition, Genetics, and Disease
- Antimicrobial Peptides and Activities
- Flowering Plant Growth and Cultivation
- Sexual function and dysfunction studies
- Dendrimers and Hyperbranched Polymers
- Bee Products Chemical Analysis
- Toxin Mechanisms and Immunotoxins
- Pesticide Residue Analysis and Safety
- Body Contouring and Surgery
- Migraine and Headache Studies
- Olfactory and Sensory Function Studies
- Salivary Gland Disorders and Functions
- Reconstructive Surgery and Microvascular Techniques
- Smart Agriculture and AI
- Nanocomposite Films for Food Packaging
- biodegradable polymer synthesis and properties
- Lipid Membrane Structure and Behavior
- Protein Interaction Studies and Fluorescence Analysis
- Biochemical effects in animals
Saveetha University
2023
Career Point University
2022
Stanley Medical College
2021
Jawaharlal Nehru Technological University Anantapur
2021
Bharathidasan University
2019
Anna University, Chennai
2019
The present work aimed to develop a chronotherapeutic system of valsartan (VS) using nanocrystal formulation improve dissolution. VS nanocrystals (VS-NC) were fabricated modified anti-solvent precipitation by employing Box−Behnken design optimize various process variables. Based on the desirability approach, containing 2.5% poloxamer, freezing temperature −25 °C, and 24 h freeze-drying time can fulfill optimized formulation’s requirements result in particle size 219.68 nm, 0.201...
Transferosomes are one of the vesicular carriers that have received extensive research and attention recently because their capacity to get beyond barriers posed by stratum corneum penetration. The intent current study is optimize evaluate proanthocyanidin (PAC) containing transferosomal transdermal gels. PAC-containing transferosomes were prepared using film hydration method then loaded into a 4% methylcellulose gel. A 23 Box-Behnken design was used PAC-loaded gel, where effects...
The potential of proniosomes as a transdermal drug delivery system for Atenolol was investigated by encapsulating the in various formulations proniosomal gel composed ratios sorbitan fatty acid esters, cholesterol, lecithin prepared Coacervation-phase separation method. objectives present study were to define effects on antihypertension activity and pharmacokinetics novel Proniosomal incorporating Atenolol. formulated systems characterized vitro size, entrapment, In vivo permeation profiles...
A novel aspiration in treatment of migraine, to provide greater therapeutic effect, overcome the side effects by complex regimen and improve patient compliance upon administering bucco-adhesive tablet formulations sumatriptan succinate which have not been tested literally.This study was designed develop a containing using blends different bio-adhesive polymeric combinations such as hydroxy propyl methyl cellulose K4M, sodium carboxy cellulose, Carbopol 934P with backing layer ethyl direct...
With the recent advances of nanotechnology, dendrimers are emerging as a highly attractive class drug delivery vectors for cancer therapy. Dendrimers multifunctional smart Nanocarriers to deliver one or more therapeutic agent safely and selectively cells. The high level control over synthesis dendritic architecture makes nearly perfect (spherical) nanocarrier site-specific delivery. presence functional groups in exterior also permits addition other moieties that can actively target certain...
Abstract Background There are many circumstances where chronic disease is associated with other disorders, especially in diseases such as diabetes noncommunicable risk factors, hypertension. The current therapies for treating comorbid limited and challenging due to the difficulties overcoming side effects from complex therapeutic treatment regimen. present study aimed develop optimize combinational nano invasomal gel of Glibenclamide (GLB) Atenolol (ATN) a novel combination therapy diabetic...
Formulation and evaluation of oral disintegrating tablets montelukast sodium desloratidine - The objective the present
Ultra performance liquid chromatography method was developed for the simultaneous estimation of Artemether (AMT) and Lumefantrine (LFT) in Tablet dosage form. Chromatogram run through X-bridge C18 100 x 2.1 mm, 3.5m. Mobile phase containing Buffer 0.01N KH2PO4 (3.5pH): Acetonitrile taken ratio 55:45 pumped column at a flow rate 0.3ml/min. used this KH2PO4. Temperature maintained 30°C. Optimized wavelength selected 215nm. Retention time AMT LFT were found to be 0.787 min 1.572min. %RSD 0.7...
A new, simple, reliable, fast, sensitive and economical RP-HPLC method was developed validated for simultaneous estimation of two fixed-dose combinations frequently prescribed in coexisted chronic diseases such as diabetes (GLB) hypertension (ATN) bulk the first time. The mobile phase used chromatographic runs consisted 0.01N potassium dihydrogen ortho phosphate (pH 4.8) acetonitrile (55:45, v/v). separation achieved on column (BDS C18 250 x 2.1mm, 1.6m) using isocratic mode. Drug peaks were...
A training programme for the food service personnel from old age home and impart diet counseling to elderly people, based on dietary knowledge, practices assessed its impact.The effectiveness of was evaluated after an interval one month using same checklist
There are numerous circumstances where chronic disease is associated with other disorders, especially in diseases like diabetes noncommunicable risk factors, such as hypertension. This study shows a novel and innovative combinational proniosomal delivery of combination to beat the reactions by complex therapeutic regimen, improve patient compliance after controlling transdermal Glibenclamide (GLB) Atenolol (ATN) which have not been tried actually. To achieve above reason, proniosomes were...