A5073248091- Breast Cancer Treatment Studies
- Thyroid Cancer Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
- Big Data and Business Intelligence
- RNA modifications and cancer
- Data Mining Algorithms and Applications
- Pancreatic and Hepatic Oncology Research
- HER2/EGFR in Cancer Research
- Natural product bioactivities and synthesis
- Atherosclerosis and Cardiovascular Diseases
- Metabolism, Diabetes, and Cancer
- Pharmacological Effects of Medicinal Plants
- Cancer Immunotherapy and Biomarkers
- Cancer, Hypoxia, and Metabolism
- Advanced Breast Cancer Therapies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Autophagy in Disease and Therapy
- Bone Metabolism and Diseases
- Colorectal Cancer Screening and Detection
- MicroRNA in disease regulation
- Genomics, phytochemicals, and oxidative stress
- Ferroptosis and cancer prognosis
- Tea Polyphenols and Effects
- Gallbladder and Bile Duct Disorders
Affiliated Hospital of Qingdao University
2023-2024
Qingdao University
2023-2024
First Affiliated Hospital of Jinan University
2021-2023
Jinan University
2023
The precancerous disease of breast cancer is an inevitable stage in the tumorigenesis and development neoplasms. Quercetin (Que) has shown great potential treatment by inhibiting cell proliferation regulating T function. γδ cells are a class nontraditional that have long attracted attention due to their immunotherapy. In this study, we revealed immunomodulatory function Que through regulation JAK/STAT1 signaling pathway, which was followed synergistic killing cells.In experimental design,...
Abstract Kaempferol has been suggested to be an effective anticancer agent in several malignant tumors. However, its function and mechanisms breast precancerous lesions remain largely elusive. Here, we showed that kaempferol induced excessive mitochondrial fission damage with activated factor (MFF)‐mediated dynamin‐related protein (DRP) 1 translocation. As a result, the PTEN‐induced putative kinase (PINK1)/Parkin signaling pathway was activated, accompanied by mitophagy reduced mass cells....
Breast carcinoma is a multistep progressive disease. Precancerous prevention seems to be crucial. β-Boswellic acid (β-BA), the main component of folk medicine Boswellia serrata ( B. ), has been reported effective in various diseases including tumors. In this work, we demonstrated that β-BA could inhibit breast precancerous lesions rat disease models. Consistently, suppress proliferation and induce apoptosis on MCF-10AT without significantly influencing MCF-10A. Kyoto Encyclopedia Genes...
<title>Abstract</title> The development of gallstones is closely related to diet. As the prevalence increases, it crucial identify risk factors predict gallstones. Data from 2017–2020 U.S. National Health and Nutrition Examination Survey (NHANES) were analyzed, 5,150 participants randomly divided into a training set validation in 7:3 ratio. Variables screened via Least absolute shrinkage selection operator (LASSO) regression. Multilayer perceptron (MLP), support vector machines (SVM),...
Abstract Background: immunotherapy with immune checkpoint inhibitors (ICIs) for solid tumors had significantly improved overall survival (OS). Positive response to PD-1/PD-L1 blockades was observed in the treatment of tumors. Breast cancer (BC) patients are no exception. However, efficacy immunocheckpoint therapy BC remains poor. A particularly important factor is lack studies on expression patterns checkpoints patients. Results: It found that increased PD-1, PD-L1, STAT1, CTLA-4 associated...