A5071668974- Cell Adhesion Molecules Research
- Statistical Distribution Estimation and Applications
- Platelet Disorders and Treatments
- Angiogenesis and VEGF in Cancer
- NF-κB Signaling Pathways
- Natural product bioactivities and synthesis
- TGF-β signaling in diseases
- Cellular Mechanics and Interactions
- Pharmacological Effects of Natural Compounds
- Venomous Animal Envenomation and Studies
- Glutathione Transferases and Polymorphisms
- Radiation Dose and Imaging
- Global Cancer Incidence and Screening
- Probabilistic and Robust Engineering Design
- Markov Chains and Monte Carlo Methods
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Effects of Radiation Exposure
Universidade do Estado do Rio de Janeiro
2021-2023
Hospital Universitário Clementino Fraga Filho
2023
Universidade Federal do Rio de Janeiro
2016-2023
Abstract Hypercoagulability, a major complication of metastatic cancers, has usually been treated with heparins from natural sources, or their synthetic derivatives, which are under intense investigation in clinical oncology. However, the use heparin challenging for patients risk severe bleeding. While systemic administration heparins, preclinical models, shown primarily attenuating effects on metastasis, direct effect established solid tumors generated contradictory outcomes. We...
In vitro experiments were conducted in this work to analyze the proliferation of tumor (DU-145) and normal (macrophage RAW 264.7) cells under influence a chemotherapeutic drug (doxorubicin). Approximate Bayesian Computation (ABC) was used select among four competing models represent number estimate model parameters, based on experimental data. For one case, selected validated replicated experiment, through solution state estimation problem with particle filter algorithm, thus demonstrating...
Abstract Introduction: Breast cancer (BC) is the most common female malignancy worldwide. For definitive treatment of MC, radiotherapy can be used, as an important component, and uses ionizing radiation (IR). Studies reveal potential capacity IR to promote metastasis. The clinical response BC related radiosensitivity resistance irradiated cells, which associated with clonogenic activity sensitivity radiation. Unsuccessful increases risk local distant recurrence. Methodology: Three breast...