A5023444007- Cell Adhesion Molecules Research
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Heat shock proteins research
- Protease and Inhibitor Mechanisms
- Biochemical and Structural Characterization
- Venomous Animal Envenomation and Studies
- Porphyrin and Phthalocyanine Chemistry
- Rabies epidemiology and control
- Bone health and treatments
- Enzyme Structure and Function
- S100 Proteins and Annexins
- TGF-β signaling in diseases
- Cancer Treatment and Pharmacology
- Colorectal and Anal Carcinomas
- Skin Protection and Aging
- HER2/EGFR in Cancer Research
- Peptidase Inhibition and Analysis
- Gastric Cancer Management and Outcomes
- thermodynamics and calorimetric analyses
- Bone Metabolism and Diseases
- ATP Synthase and ATPases Research
- Protein Structure and Dynamics
- Metastasis and carcinoma case studies
Universidade Federal de São Carlos
2016-2023
Universidade de São Paulo
2016-2023
Vanderbilt University Medical Center
2021
Integrins participate in the pathogenesis and progression of tumors at many stages during metastatic cascade. However, current evidence for role integrins breast cancer is contradictory seems to be dependent on tumor stage, differentiation status, microenvironmental influences. While some studies suggest that loss α2β1 enhances metastasis, other this integrin pro-tumorigenic. few have looked context bone metastasis. In study, we aimed understand metastasis bone. To address this, utilized...
Matrix metalloproteinases (MMPs) are key players in tumor progression, helping cells to modify their microenvironment, which allows cell migration secondary sites. The role of integrins, adhesion receptors that connect the extracellular matrix, MMP expression and activity has been previously suggested. However, mechanisms by integrins control not completely understood. Particularly, α2β1 integrin, one major collagen I receptors, studied. Alternagin-C (ALT-C), a...