Mohamed Arafa
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Sexual Differentiation and Disorders
- Sexual function and dysfunction studies
- Hormonal and reproductive studies
- Male Reproductive Health Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Ovarian function and disorders
- Urologic and reproductive health conditions
- Sexuality, Behavior, and Technology
- Urinary Bladder and Prostate Research
- Genital Health and Disease
- Testicular diseases and treatments
- Demographic Trends and Gender Preferences
- Selenium in Biological Systems
- Marriage and Sexual Relationships
- Reproductive Health and Contraception
- Metabolism and Genetic Disorders
- Global Maternal and Child Health
- Anesthesia and Pain Management
- COVID-19 and healthcare impacts
- Meta-analysis and systematic reviews
- Assisted Reproductive Technology and Twin Pregnancy
- Urological Disorders and Treatments
Cairo University
2016-2025
Hamad Medical Corporation
2016-2025
Weill Cornell Medical College in Qatar
2018-2025
Qatar University
2025
Assiut University
2022-2025
Cleveland Clinic
2019-2024
Hamad General Hospital
2015-2024
Tanta University
2024
NationalRad (United States)
2024
Salmaniya Medical Complex
2024
Nonobstructive azoospermia (NOA) affects 1% of the male population; however, despite state-of-the-art clinical assessment, for most patients cause is unknown. We capitalized on an analysis multiplex families in Middle East to identify highly penetrant genetic causes.We used whole-exome sequencing (WES) 8 consanguineous and combined newly discovered genes with previously reported ones create a NOA gene panel, which was additional variants 75 unrelated idiopathic subjects 74 fertile...
Varicocele is a common problem among infertile men. repair (VR) frequently performed to improve semen parameters and the chances of pregnancy. However, there lack consensus about diagnosis, indications for VR its outcomes. The aim this study was explore global practice patterns on management varicocele in context male infertility.Sixty practicing urologists/andrologists from 23 countries contributed 382 multiple-choice-questions pertaining management. These were condensed into an online...
To assess seminal oxidation-reduction potential (ORP) and sperm DNA fragmentation (SDF) in male infertility their relationships with morphology fertile infertile men.Prospective case-control study comparing the findings of men (n = 1168) to those confirmed fertility 100) regarding demographics semen characteristics (conventional advanced tests). Spearman rank correlation assessed between ORP, SDF, different morphological indices. Means ORP SDF were variable levels normal amongst all...
Antioxidants are used in the empirical treatment of infertile men. The aim this study was to evaluate effects antioxidant therapy on conventional semen parameters and advanced sperm function tests men seeking fertility treatment. A total 148 unknown etiology were divided into idiopathic (n = 119) unexplained male infertility (UMI; n 29). All participants treated with supplement ‘FH PRO for Men’ a period three months. Compared pretreatment results, there significant improvement including...
The coronavirus disease (COVID)-19 pandemic forced an unprecedented period of challenge to the NHS in UK where hip fractures elderly population are a major public health concern. There approximately 76,000 each year which make up substantial proportion trauma workload average orthopaedic unit. This study aims assess impact COVID-19 on fracture care service and emerging lessons withstand any future outbreaks.Data were collected retrospectively 157 admitted from March May 2019 2020. 2020 group...
According to the World Health Organization (WHO), oxidative stress (OS) is a significant contributor male infertility. Seminal OS can be measured by number of assays, all which are either costly or time sensitive and/or require large semen volume and complex instrumentation. One less expensive alternative quantify oxidation-reduction potential (ORP) with MiOXSYS. In this international multi-center study, we assessed whether ORP levels MiOXSYS could distinguish samples that fall within 2010...
Purpose: The use of antioxidants is common practice in the management infertile patients.However, there are no established guidelines by professional societies on antioxidant for male infertility.Materials and Methods: Materials Using an online survey, this study aimed to evaluate pattern reproductive specialists determine clinical utility oxidative stress (OS) testing prescriptions treat infertility.Results: Results: Responses from 1,327 participants representing 6 continents, showed...
Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of World Health Organization laboratory manual for examination and processing human semen. Many conditions risk factors have been associated with elevated SDF; therefore, it is important identify population infertile men who might benefit from this test. The purpose study investigate global practices related indications SDF testing, compare relevant professional society guideline recommendations, provide expert...
The purpose of this meta-analysis is to study the impact varicocele repair in largest cohort infertile males with clinical by including all available studies, no language restrictions, comparing intra-person conventional semen parameters before and after varicoceles.
Sperm DNA fragmentation (SDF) has emerged as an important biomarker in the assessment of male fertility potential with contradictory results regarding its effect on ICSI. The aim this study was to evaluate intracytoplasmic sperm injection (ICSI) outcomes patients high SDF using testicular versus ejaculated spermatozoa. This is a prospective 36 men high-SDF levels who had previous ICSI cycle from their ejaculates. A subsequent performed spermatozoa retrieved through aspiration. Results prior...
Elevated levels of reactive oxygen species (ROS) are detected in 25% to 80% infertile men. They involved the pathology male infertility. Understanding effect increasing ROS on differential expression sperm proteins is important understand cellular processes and or/pathways that may be implicated The aim this study was examine differentially expressed (DEPs) spermatozoa from patients with low, medium high levels.A total 42 men presenting for infertility 17 proven fertile were enrolled study....