A5047944565- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Reproductive tract infections research
- Lymphatic System and Diseases
- Reproductive Health and Contraception
- Reproductive System and Pregnancy
- Mosquito-borne diseases and control
- Syphilis Diagnosis and Treatment
- Insects and Parasite Interactions
- Cervical Cancer and HPV Research
- Health Systems, Economic Evaluations, Quality of Life
- Global Maternal and Child Health
- Dysphagia Assessment and Management
- Venomous Animal Envenomation and Studies
- Nematode management and characterization studies
- Adolescent Sexual and Reproductive Health
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Emergency and Acute Care Studies
- Viral Infections and Outbreaks Research
- Bacillus and Francisella bacterial research
- Drug-Induced Adverse Reactions
- Vector-borne infectious diseases
- Disaster Response and Management
RTI International
2014-2024
Johns Hopkins Medicine
2023
Johns Hopkins University
2023
World Health Organization Regional Office for the Western Pacific
2013
Emory University
2007
The Task Force for Global Health
2006-2007
Because lymphatic filariasis (LF) elimination efforts are hampered by a dearth of economic information about the cost mass drug administration (MDA) programs (using either albendazole with diethylcarbamazine [DEC] or ivermectin), multicenter study was undertaken to determine costs MDA interrupt transmission infection LF. Such results particularly important because LF have necessary diagnostic and treatment tools eliminate disease as public health problem globally, already 2006, Global...
This report summarizes the 7th meeting of Global Alliance to Eliminate Lymphatic Filariasis (GAELF), Washington DC, November 18-19, 2012. The theme, "A Future Free Filariasis: Reaching Vision by Scaling Up, Down and Out", emphasized new strategies partnerships necessary reach 2020 goal elimination lymphatic filariasis (LF) as a public-health problem.
Background To reach the global goal of elimination lymphatic filariasis as a public health problem by 2020, national programs will have to implement series transmission assessment surveys (TAS) determine prevalence disease evaluation unit. It is expected that 4,671 be required 2020. Planning in advance for costs associated with these essential ensure resources are available this program activity. Methodology and Findings Retrospective cost data was collected from reports 13 countries which...
Achieving elimination of lymphatic filariasis (LF) as a public health problem requires minimum five effective rounds mass drug administration (MDA) and demonstrating low prevalence in subsequent assessments. The first assessments recommended by the World Health Organization (WHO) are sentinel spot-check sites—referred to pre-transmission assessment surveys (pre-TAS)—in each implementation unit after MDA. If pre-TAS shows that site has been lowered less than 1% microfilaremia or 2%...
We conducted a cost analysis of Haiti's Ministry Public Health and Population neglected tropical disease program, Projet des Maladies Tropicales Negligées collected data for 9 55 communes participating in the May 2008–April 2009 mass drug administration (MDA). The Program partnered with IMA World Hôpital Ste. Croix to implement MDA treatment lymphatic filariasis soil-transmitted helminthiasis by using once year albendazole diethylcarbamazine population approximately 8 million persons....
Endemicity of lymphatic filariasis (LF) in Cambodia was proven 1956 when microfilariae were detected mosquitos the Kratié province. In 2001, an extensive study confirmed presence both Brugia malayi and Wuchereria bancrofti microfilariae. 2003, Ministry Health established a national task force to develop policies strategies for controlling eliminating neglected tropical diseases (NTDs), with goal LF by 2015. This article summarizes work accomplished eliminate as public health problem...
The Global Programme to Eliminate Lymphatic Filariasis recommends the transmission assessment survey (TAS) as preferred methodology for determining whether mass drug administration can be stopped in an endemic area. Because of limited experience available globally with use Brugia Rapid™ tests conducting TAS spp. areas, we explored relationship between antibody test results and infection detected by microfilaremia different epidemiological settings. study analyzes responses all ages at three...
Purpose: Following interventions against trachoma in Viet Nam, impact surveys conducted 2003–2011 suggested that was no longer a public health problem. In 2014, we undertook surveillance to estimate prevalence of trachomatous inflammation—follicular (TF) and trichiasis.Methods: A population-based survey undertaken 11 evaluation units (EUs) encompassing 24 districts, using Global Trachoma Mapping Project methods. two-stage cluster sampling design used each EU, whereby 20 clusters 60 children...
Trachoma programs use annual antibiotic mass drug administration (MDA) in evaluation units (EUs) that generally encompass 100,000-250,000 people. After one, three, or five MDA rounds, undertake impact surveys. Where survey prevalence of trachomatous inflammation-follicular (TF) 1- to 9-year-olds is ≥ 5%, 1 additional rounds are recommended before resurvey. Impact costs, and the proportion surveys returning TF 5% (the failure rate or, less pejoratively, continuation rate), therefore influence...
Background The World Health Organization (WHO) recommends that countries ensure morbidity management and disability prevention (MMDP) services are available to all lymphedema hydrocele patients in lymphatic filariasis (LF)-endemic areas. first step ensuring the availability of MMDP is understand number distribution people with hydrocele. We examined burden lymphoedema hydrocoele using different patient estimation approaches employed endemic districts Beneshangul-Gumuz Tigray regions...
Abstract As neglected tropical disease programs rely on participation in rounds of mass drug administration (MDA), there is concern that individuals who have never been treated could contribute to ongoing transmission, posing a barrier elimination. Previous research has suggested the size and characteristics never-treated population may be important but not sufficiently explored. To address this critical knowledge gap, four meetings were held from December 2020 May 2021 compile expert...
Purpose We aimed to estimate the prevalence of trachomatous inflammation–follicular (TF) in 1–9-year-olds and trichiasis (TT) unknown health system ≥15-year-olds Benishangul Gumuz (BGZ) region, Ethiopia. This will help assess progress towards elimination trachoma as a public problem determine need for future interventions against region.Methods Cross-sectional population-based surveys were conducted four evaluation units (EUs) BGZ using World Health Organization-recommended survey...
Background The World Health Organization (WHO) in collaboration with partners is developing a toolkit of resources to guide lymphatic filariasis (LF) morbidity management and disability prevention (MMDP) implementation evaluation. Direct health facility inspection the preferred method for documenting readiness country programme provide quality lymphoedema services, one three MMDP criteria used demonstrate elimination LF as public problem. Methodology/Principal findings As component tool...
Abstract The 2021–2030 Neglected Tropical Diseases road map calls for intensified cross-cutting approaches. By moving away from vertical programming, the integration of platforms and intervention delivery aims to improve efficiency, cost-effectiveness programme coverage. Drawing on direct experiences authors, this article outlines key elements successful integrated surveys, challenges encountered, as well future opportunities threats such surveys. There are multiple advantages. Careful...
Background Ethiopia aims to eliminate lymphatic filariasis by 2020, through a dual approach of mass drug administration interrupt transmission and morbidity control which includes making hydrocele surgery available in all endemic areas. Locating patients requiring surgery, providing high quality surgeries, following up are formidable challenges for many resource-challenged or difficult-to-reach communities. To date, has only occurred when patient the knowledge, time resources travel regional...
Assuring availability of services for patients with lymphedema is required countries to be validated as having achieved elimination lymphatic filariasis (LF). A direct inspection protocol (DIP) tool, designed measure the readiness provide quality management services, has recently been developed. The DIP tool includes 14 indicators across six themes: trained staff, case and education materials, water infrastructure, medicines commodities, patient tracking system, staff knowledge. We evaluated...
Following baseline surveys in 2013 and 2014, trachoma elimination interventions, including three rounds of azithromycin mass drug administration (MDA), were implemented 13 woredas (administrative districts) Gambella Regional State, Ethiopia. We conducted impact to determine if thresholds have been met or additional interventions are required.Cross-sectional population-based combined into five evaluation units (EUs), 6─12 months after their last MDA round. A two-stage systematic (first stage)...
Neglected tropical diseases (NTDs) cause significant morbidity and mortality worldwide impose a large economic burden on endemic countries [1]. In 2006, the United States Agency for International Development (USAID) founded NTD Control Program to target five NTDs in African, Asian, Latin American countries, namely, lymphatic filariasis (LF), onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH), trachoma; three targeted STH infections are ascariasis, hookworm, trichuriasis....
Abstract When COVID-19 emerged as a global pandemic, the World Health Organization (WHO) recommended pause in delivery of neglected tropical disease preventative chemotherapy and surveillance. The Act to End NTDs | East program (Act East) worked with country (NTD) programs develop, support, implement guidelines that allowed NTD service surveillance resume. This paper examines those adaptations made support numerous countries, over discrete time period, resume operations. also examined how...
Abstract Background The Emergency Department (ED) is a safety net for vulnerable patients, and where almost 50% of patients with Mpox initially presented care. We hypothesized that insufficient healthcare provider knowledge expertise Orthopoxvirus outbreaks, compounded by the social stigma experienced at risk acquiring Mpox, may impact quality care received in this venue. Methods All who Johns Hopkins Health System Departments (N=4) were invited to participate post-discharge telephonic...