A5083337409- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Biliary and Gastrointestinal Fistulas
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Pediatric Hepatobiliary Diseases and Treatments
- Gastroesophageal reflux and treatments
- Esophageal Cancer Research and Treatment
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Minimally Invasive Surgical Techniques
- Eosinophilic Esophagitis
- Hemostasis and retained surgical items
- Platelet Disorders and Treatments
- Dysphagia Assessment and Management
- Appendicitis Diagnosis and Management
- Pancreatitis Pathology and Treatment
- Diverticular Disease and Complications
- Tracheal and airway disorders
- Genetic factors in colorectal cancer
Chinese University of Hong Kong
2016-2025
AstraZeneca (Japan)
2024
Prince of Wales Hospital
2014-2023
Eastern Virginia Medical School
2022-2023
University of Virginia
2023
University of North Carolina at Chapel Hill
2023
Defence Science and Technology Group
2021
Stanford Medicine
2013-2020
Mayo Clinic in Florida
2019
University of Hong Kong
2014-2017
Many patients who have had upper gastrointestinal bleeding continue to take low-dose aspirin for cardiovascular prophylaxis or other nonsteroidal antiinflammatory drugs (NSAIDs) musculoskeletal pain. It is uncertain whether infection with Helicobacter pylori a risk factor in such patients.
Concurrent therapy with a proton-pump inhibitor is standard treatment for patients receiving aspirin who are at risk ulcer. Current U.S. guidelines also recommend clopidrogel have major gastrointestinal intolerance of aspirin. We compared clopidogrel plus esomeprazole the prevention recurrent bleeding from ulcers in high-risk patients.We studied took to prevent vascular diseases and presented ulcer bleeding. After had healed, we randomly assigned were negative Helicobacter pylori receive...
Background: It is uncertain whether aspirin therapy should be continued after endoscopic hemostatic in patients who develop peptic ulcer bleeding while receiving low-dose aspirin. Objective: To test that continuing with proton-pump inhibitors control of was not inferior to stopping therapy, terms recurrent adults cardiovascular or cerebrovascular diseases. Design: A parallel randomized, placebo-controlled noninferiority trial, which both and clinicians were blinded treatment assignment,...
After endoscopic treatment to control bleeding of peptic ulcers, recurs in 15 20 percent patients. In a prospective, randomized study, we compared retreatment with surgery after initial endoscopy. Over 40-month period, 1169 3473 adults who were admitted our hospital ulcers underwent endoscopy reestablish hemostasis. Of 100 patients recurrent bleeding, 7 cancer and 1 patient cardiac arrest excluded from the study; 48 randomly assigned undergo immediate 44 surgery. The type operation used was...
Despite advances in endoscopic and pharmacological treatment for peptic ulcer bleeding (PUB), mortality remains at 5-10% worldwide. Our aim was to investigate the causes of death a prospective cohort PUB tertiary referral center.Between 1993 2005, all patients with upper gastrointestinal (UGIB) admitted Prince Wales Hospital were prospectively registered. Demographic data, characteristics ulcer, pharmacological, endoscopic, surgical therapy, documented. Mortality cases classified as (A)...
It is recommended that patients with acute upper gastrointestinal bleeding undergo endoscopy within 24 hours after gastroenterologic consultation. The role of performed time frames shorter than has not been adequately defined.To evaluate whether urgent improves outcomes in predicted to be at high risk for further or death, we randomly assigned overt signs and a Glasgow-Blatchford score 12 higher (scores range from 0 23, scores indicating death) 6 (urgent-endoscopy group) between...
<h3>Objective</h3> Non-alcoholic fatty liver disease (NAFLD) affects 20–40% of the general adult population. Due to shared risk factors, it is postulated that NAFLD patients have an increased colorectal neoplasm and should be a target group for screening. The aim this study was examine prevalence in relation severity histology. <h3>Design</h3> Cross-sectional study. <h3>Setting</h3> University hospital with case recruitment from community clinics. <h3>Patients</h3> Subjects aged 40–70 years...
Objective The optimal management of acute cholecystitis in patients at very high risk for cholecystectomy is uncertain. aim the current study was to compare endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD) percutaneous cholecystostomy (PT-GBD) as a definitive treatment these under randomised controlled trial. Design Consecutive suffering from calculous but were high-risk recruited. primary outcome 1-year adverse events rate. Secondary outcomes include technical and clinical...
Based on experiences and the literature, our objective is to provide practical suggestions for performing endoscopy in setting of novel coronavirus-19 (COVID-19) pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred as COVID-19, has become a global Human-to-human transmission occurs through secretions, aerosols, feces, contaminated environmental surfaces.1Rio C. del Malani P.N. COVID-19—new insights rapidly changing epidemic.JAMA. Epub. 2020 Mar 28; Google...
BackgroundInflammatory bowel disease is uncommon in Southeast Asia but increasing incidence. The epidemiology and phenotype of Crohn (CD) the Chinese population not well-known. purpose this study was to determine incidence, temporal trend, clinical features, risk factors, extraintestinal manifestations, treatment CD Hong Kong.
This is a consensus developed by group of expert endoscopists aiming to standardise the preparation, process and endoscopic procedural steps for diagnosis early upper gastrointestinal (GI) cancers.The Delphi method was used develop statements through identification clinical questions on diagnostic endoscopy. Three meetings were conducted consolidate voting. We systematic literature search evidence each statement. The presented in second meeting revised according comments. final voting at...
While it is recommended that patients presenting with acute upper gastrointestinal bleeding (AUGIB) should receive endoscopic intervention within 24 hours, the optimal timing still uncertain. We aimed to assess whether endoscopy postadmission would affect outcomes.We conducted a retrospective, territory-wide, cohort study healthcare data from all public hospitals in Hong Kong. Adult (age ≥18) presented AUGIB between 2013 and 2019 received therapeutic 48 hours (n=6474) were recruited....