Sze Mun Mak

ORCID: 0000-0003-0131-774X
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Long-Term Effects of COVID-19
  • Radiation Dose and Imaging
  • Mechanical Circulatory Support Devices
  • COVID-19 Clinical Research Studies
  • Radiology practices and education
  • Infective Endocarditis Diagnosis and Management
  • Advanced X-ray and CT Imaging
  • Ultrasound in Clinical Applications
  • Cardiac Arrest and Resuscitation
  • COVID-19 and healthcare impacts
  • Tracheal and airway disorders
  • Medical Imaging and Pathology Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Radiomics and Machine Learning in Medical Imaging
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiac Imaging and Diagnostics
  • Venous Thromboembolism Diagnosis and Management
  • Esophageal and GI Pathology
  • Lung Cancer Treatments and Mutations
  • Cardiac Valve Diseases and Treatments
  • Trauma Management and Diagnosis
  • Pectus Deformity Diagnosis and Treatment
  • Pulmonary Hypertension Research and Treatments
  • Acute Ischemic Stroke Management

Guy's and St Thomas' NHS Foundation Trust
2017-2025

King's College London
2025

St Thomas' Hospital
2018-2022

Royal Brompton Hospital
2020

Guy's Hospital
2019

Imperial College Healthcare NHS Trust
2016

Hammersmith Hospital
2016

Harefield Hospital
2016

The Christie NHS Foundation Trust
2009

Rationale: The natural history of recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unknown. Because fibrosis with persistent physiological deficit is a previously described feature patients recovering similar coronaviruses, treatment represents an early opportunity to modify the disease course, potentially preventing irreversible impairment.Objectives: Determine incidence and describe progression inflammatory interstitial lung (ILD) following SARS-CoV-2 when...

10.1513/annalsats.202008-1002oc article EN cc-by-nc-nd Annals of the American Thoracic Society 2021-01-12

Abstract Background Although COPD among non-smokers (NS-COPD) is common, little known about this phenotype. We compared NS-COPD subjects with smoking (S-COPD) patients in a rural Indian population using variety of clinical, physiological, radiological, sputum cellular and blood biomarkers. Methods Two hundred ninety (118 healthy, 79 S-COPD, 93 NS-COPD) performed pre- post-bronchodilator spirometry were followed for 2 years to study the annual rate decline lung function. Body plethysmography,...

10.1186/s12931-020-1310-9 article EN cc-by Respiratory Research 2020-02-12

Extracorporeal membrane oxygenation is a lifesaving therapy for patients with severe acute respiratory distress syndrome refractory to conventional mechanical ventilation. It frequently complicated by both thrombosis and hemorrhage. A markedly prothrombotic state associated high rates of venous thromboembolism has been described in coronavirus 2 (coronavirus disease 2019) infection. These have currently not during extracorporeal comparison other viral pneumonias.Retrospective observational...

10.1097/ccm.0000000000004971 article EN Critical Care Medicine 2021-04-04

Non-invasive distinction between squamous cell carcinoma and adenocarcinoma subtypes of non-small-cell lung cancer (NSCLC) may be beneficial to patients unfit for invasive diagnostic procedures or when tissue is insufficient diagnosis. The purpose our study was compare the performance random forest algorithms utilizing CT radiomics and/or semantic features in classifying NSCLC.

10.1259/bjr.20190159 article EN cc-by British Journal of Radiology 2019-06-05

Background: Early treatment of pulmonary embolism is associated with better outcomes, yet incidental PE (IPE) frequently missed. This retrospective study aims to provide an independent assessment artificial intelligence (AI) software, developed for flagging IPEs on CT scans. Methods: The included consecutive examinations 5042 unique patients (8 scanners and 3 protocols) acquired at a large NHS Trust between 01 January 2022 30 September 2022. Two radiologists blindly independently reviewed...

10.1155/rrp/9091895 article EN cc-by Radiology Research and Practice 2025-01-01

Abstract Acute pulmonary emboli can manifest as a spectrum of physiological status ranging from an incidental finding to life threatening right heart failure. We discuss the crucial role imaging plays in accurate and rapid diagnosis. In addition, features are central assessing severity presentation allowing for appropriate risk stratification escalation care. The relative strengths various modalities used management chronic thromboembolic hypertension also discussed.

10.1093/bjro/tzaf005 article EN cc-by BJR|Open 2025-04-10

•High incidence of pulmonary artery thrombosis in COVID-19 ECMO patients.•Lung ischaemia seen patients with and without visible thrombus.•Ischaemia no thrombus suggest microvascular thrombosis. AIMTo evaluate the on extracorporeal membrane oxygenation (ECMO), its correlation thrombosis.MATERIALS AND METHODSComputed tomography (CT) thorax all receiving proven pneumonitis between March May 2020 were analysed for presence extension thromboembolic disease.RESULTSFifty-one reviewed. The mean...

10.1016/j.crad.2020.07.006 article EN other-oa Clinical Radiology 2020-07-19

Many patients presenting with suspected acute coronary syndrome (ACS) have high-sensitivity cardiac troponin (hs-cTn) concentrations between rule-in and rule-out thresholds hence need serial testing, which is time consuming. The Prospective RandOmised Trial of Emergency Cardiac Computerised Tomography (PROTECCT) assessed the utility CT angiography (CCTA) in ACS, non-ischaemic ECG intermediate initial hs-cTn concentration. Patients were randomised to CCTA-guided management versus standard...

10.1136/heartjnl-2022-320990 article EN cc-by-nc Heart 2022-10-26

OBJECTIVES: Coronavirus disease 2019 has been reported to be a prothrombotic condition; however, multicenter data comparing this with other viral pneumonias in those requiring extracorporeal membrane oxygenation are lacking. We conducted study using whole-body CT examine the prevalence, severity, and nature of vascular complications coronavirus comparison patients pneumonias. DESIGN: analyzed scans for presence thrombosis (defined as pulmonary artery thrombus, venous systemic arterial or...

10.1097/ccm.0000000000005322 article EN Critical Care Medicine 2021-09-27

Objective: Interactive three-dimensional virtual models of pulmonary structures (3D-CT) may improve the safety and accuracy robotic-assisted thoracic surgery (RATS). The aim this study was to evaluate impact 3D-CT as an imaging adjunct on surgical confidence anatomical assessment for lobectomy planning. Methods: We retrospectively analyzed response 10 specialist surgeons who each reviewed pre-operative images patients undergoing lung cancer cases from June November 2018 in our institute,...

10.3389/fsurg.2021.652428 article EN cc-by Frontiers in Surgery 2021-03-29

Abstract Background Data on the prevalence and clinical impact of extrapulmonary findings at screening computed tomography (CT) initiation veno-venous extracorporeal membrane oxygenation (V-V ECMO) are limited. We aimed to identify CT following V-V ECMO initiation. hypothesized that would influence management outcome. Methods Retrospective analysis (2011–2021) admission including head, abdomen pelvis with contrast consecutive patients ECMO. identified by attending consultant radiologist were...

10.1186/s13613-023-01187-w article EN cc-by Annals of Intensive Care 2023-09-26
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