A5106731466- Pancreatic function and diabetes
- Diabetes and associated disorders
- Sleep and related disorders
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Bone Tumor Diagnosis and Treatments
- Tissue Engineering and Regenerative Medicine
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Heart Rate Variability and Autonomic Control
- Parathyroid Disorders and Treatments
- Gastrointestinal Tumor Research and Treatment
- Congenital Diaphragmatic Hernia Studies
- Renal and related cancers
- Spinal Hematomas and Complications
- Sleep and Wakefulness Research
- Helicobacter pylori-related gastroenterology studies
- PI3K/AKT/mTOR signaling in cancer
- Diabetes Management and Research
- FOXO transcription factor regulation
- Lymphoma Diagnosis and Treatment
- Case Reports on Hematomas
- Tumors and Oncological Cases
- Estrogen and related hormone effects
- CNS Lymphoma Diagnosis and Treatment
Cell Biotech (South Korea)
2025
Samsung Medical Center
2003-2024
Sungkyunkwan University
2003-2024
Hallym University Sacred Heart Hospital
2012-2019
University Gastroenterology
2019
Hallym University
2009-2014
Seoul National University
2012
Chonnam National University
2009
The great majority of primary central nervous system lymphoma (PCNSL) is known to be B-lineage, with T-cell PCNSL (T-PCNSL) accounting for <5%. We report an unusually high incidence among the PCNSLs originated in a large general-care hospital metropolitan Seoul area. (n = 42) accrued from April 1995 through June 2001 were reviewed histologic and clinical features, immunohistochemical staining was done CD3, CD20, CD4, CD8, Bcl-6, CD10. Clonal rearrangements TCR-gamma IgH genes studied...
Abstract Background The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis. Previous studies have found that perinatal tissue (umbilical cord, UC; placenta, PL)-derived mesenchymal stem cells (MSCs) reduce several organs. However, their effects on human are poorly understood. This study investigated the anti-fibrogenic properties mechanisms MSCs derived from UC PL (UC/PL-MSCs)...
Abstract This study investigated the safety and efficacy of MR-MC-01, a mesenchymal stem cell therapy derived from human embryonic cells, in patients with interstitial cystitis (IC), particularly those Hunner lesions unresponsive to pentosan polysulfate sodium (PPS). Conducted as prospective, randomized, double-blind, placebo-controlled phase I/IIa clinical trial, it enrolled 22 patients, six completing I 16 participating IIa. Phase tested 2 doses (2.0 × 107 5.0 cells) determine maximum...
Although germline mutations of met proto-oncogene on human chromosome 7q31-34 have been known as useful molecular markers hereditary papillary renal cell carcinoma (RCC), the expression MET, a product proto-oncogene, has not fully studied in sporadic RCC, along with its clinical significance. We investigated MET by immunohistochemistry 182 cases neoplasm encompassing 145 25 urothelial carcinomas pelvis, and 12 oncocytomas. was diffusely strongly expressed 90% all collecting duct carcinomas,...
Objective: To assess the relationship between apparent diffusion coefficient (ADC) values on diffusion-weighted magnetic resonance (MR) imaging and pathologic measures of a tumor using prostate cancer xenograft model.Materials Methods: Eighteen athymic nude mice with 36 PC-3-induced tumors were sacrificed to obtain specimens immediately after MR in order compare findings images those seen pathological specimens.Using high-field small-animal scanner, T1-and T2-weighted DW was performed.Tumors...
Pancreatic islet transplantation is a promising method for curing diabetes mellitus. We proposed in this study molecularly engineered cell clusters (ICCs) that could overcome problems posed by circumstances and host's immune reactions. A gene containing highly releasable exendin-4, an insulinotropic protein, was delivered into single cells to enhance glucose sensitivity; thereafter, the were reaggregated small size ICCs. Then surface of ICCs modified with biocompatible poly(ethylene...
Gastric 'indefinite for neoplasm/dysplasia' (IFND) is a borderline lesion that difficult to diagnose as either regenerative or neoplastic. There need guidance in the identification of subset patients, who have an IFND with higher risk malignant potential, enable stratification and optimal management.To determine clinical pathologic factors accurate diagnosis gastric lesions.In total, 461 lesions diagnosed via biopsy were retrospectively evaluated. Endoscopic resection (n = 134), surgery 22),...
Metastatic calcification is rare; it found during autopsy in patients who underwent hemodialysis. Diffuse calcium precipitation of small and medium-sized cutaneous vessels, known as calciphylaxis, can result progressive tissue necrosis secondary to vascular calcification. This condition most commonly involves the skin; however, a rare occurrence visceral calciphylaxis has been reported. Here we report on an case. Despite thorough evaluation, even performing autopsy, underlying cause...
Perivascular epithelioid cell tumor (PEComa) is an extremely rare mesenchymal tumor, which can arise in a wide array of anatomic locations, and characterized by its myelomelanocytic phenotype unpredictable natural history. Specifically, PEComas, occur nonclassic distributions, are known as PEComa–not otherwise specified (PEComa‐NOS) [1]. To the best our knowledge, total 234 cases PEComasNOS have been reported English published reports. Of those, 47 were uterine PEComas cases, included 31...
Rhabdomyosarcoma is a highly aggressive malignant tumor with an incidence of 1/500,000 children per year. It originates from mesenchymal cell to invade soft tissue, developing into tumor. consists the following four pathologic groups-embryonal, botryoid, alveolar, and pleomorphic type. While head neck most common site embryonal rhabdomyosarcoma, pharynx rarely reported as primary rhabdomyosarcoma. Recently, 5-year survival rate rhabdomyosarcoma has been greatly increased by combining therapy...
More than 90% cases of chronic gastrointestinal bleeding can be diagnosed by upper endoscopy and/or colonoscopy, and therefore, obscure has been defined as unknown origin that persists after these conventional endoscopic evaluation. Gastrointestinal stromal tumors (GISTs) are rare tumors, but the most common form mesenchymal tract. Small bowel is second primary site for GISTs, accounts 2-10% sites. GISTs usually present a sporadic solitary tumor, minority multiple discovered forms hereditary...
Goblet cell carcinoid tumor of the appendix (GCTA) is a with histological features both adenocarcinoma and tumors. The most common clinical presentation GCTA acute appendicitis, although small bowel obstruction has been reported as rare symptom GCTA. However, to best our knowledge, CT feature obstructions in patients not date. Here, we present case patient caused by extensive infiltration at terminal ileum distal ileum.
Objective: This study investigated the association between anxiety symptoms in elderly insomnia patients and heart rate variability (HRV) parameters. Methods: In total, 46 (67.91±5.61 years old, 11 males, 35 females) were enrolled. The Pittsburgh Sleep Quality Index, Beck Anxiety Inventory, Albany Panic Phobia Questionnaire (APPQ), Penn State Worry Questionnaire, Liebowitz Social Scale used to measure sleep quality anxiety. Resting-state HRV was also obtained. associations measures analyzed....