A5019603084- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Cardiac Health and Mental Health
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- MicroRNA in disease regulation
- Mental Health Treatment and Access
- Mental Health Research Topics
- Stress Responses and Cortisol
- Schizophrenia research and treatment
- Psychosomatic Disorders and Their Treatments
- Mental Health and Psychiatry
- Circular RNAs in diseases
- COVID-19 Impact on Reproduction
- Suicide and Self-Harm Studies
- Health, psychology, and well-being
- Health and Wellbeing Research
- Family Support in Illness
- Neurological Disorders and Treatments
- Heart Rate Variability and Autonomic Control
- Neurological and metabolic disorders
- Attachment and Relationship Dynamics
- Phosphodiesterase function and regulation
- Infectious Encephalopathies and Encephalitis
- Restraint-Related Deaths
Victor Babeș University of Medicine and Pharmacy Timișoara
2015-2025
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2020-2024
Clinical Emergency Hospital Bucharest
2014
West University of Timişoara
2013
Camera de Comerț Industrie și Agricultură Timișoara
2011
Significant progress was made in the understanding etiopathogenic factors related to MDD, including through research on role of micro RNAs (miRs). We investigated plasma miRs as potential markers for MDD patients treated with antidepressants.At initiation and at end twelve weeks treatment, blood samples were collected a structured diagnostic interview standardized depression rating scale presence severity major done. The average decrease HAMD score 76.89%. Plasma miR expression profiling...
Increasing amount of data reveal that suicide risk is a real phenomenon among perinatal women, determined by several other psychopathological conditions with depression being just one them. This study aimed to investigate the role personality dimensions on occurrence ideation during period.A longitudinal prospective was performed in pregnant women who were monitored at university-based obstetrical care units our county. Recruited reassessed between 6 and 8 weeks into their postnatal period....
Rutin (Rut) is a natural flavonol, well-known for its broad-spectrum of therapeutic effects, including antioxidant and antitumoral activities; still, it has reduced clinical outcome due to limited solubility in aqueous solutions. To overcome this drawback, study proposes novel formulation rutin as proniosomal gel cutaneous applications. The was prepared by coacervation phase-separation method complies with the standard requirements terms particle size (140.5 ± 2.56 nm), zeta potential...
The most prevalent mental illness worldwide and the main contributor to suicide disability is major depressive disorder. Major disorder now diagnosed treated based on patient’s statement of symptoms, status tests, clinical behavioral observations. central element this review increased need for an accurate diagnostic method. In context, present research aims investigate potential role two non-coding RNA species (microRNA long RNA) in peripheral blood samples brain tissue biopsy from patients...
Misophonia is a neurophysiological disorder with behavioral implications, complex and multifactorial in origin, characterized by an atypical disproportionate emotional response to specific sounds or associated visual stimuli. Triggers include human-generated sounds, mainly related feeding breathing processes, repetitive mechanical sounds. In the triggering stimulus, patient experiences immediate, high-intensity, physical reactions that affect their quality of life social functioning. The...
(1) Background: The aim of this study was to analyze the impact pharmacogenetic-guided antidepressant therapy on 12-month evolution intensity depressive symptoms in patients with recurrent disorder (RDD) comparison a control group subjects who were treated conventionally. (2) Methods: This prospective longitudinal conducted between 2019 and 2022, evaluated by employing Hamilton Depression Rating Scale (HAM-D), Anxiety (HAM-A) Clinical Global Impressions Scale: Severity Improvement. We...
Neonatal sepsis (NS) remains a significant cause of morbidity and mortality in newborns, particularly preterm low-birthweight infants. It has been shown previously that interleukin-6 (IL-6) can predict sepsis, its non-invasive determination be performed quickly, leading to the diagnosis appropriate treatment for each case. Elevated IL-6 levels have associated with early late-onset NS, showing potential as an indicator infection before onset clinical symptoms. IL-6, conjunction other...
Background and objectives: Chronic obstructive pulmonary disease (COPD) is one of the most debilitating somatic diseases, having anxiety depression frequently as comorbidities. The coping style, way in which subject manages to control difficult stressful situations life, can influence its evolution also existence In this study, styles a group subjects with COPD their association intensity depressive symptoms well medical determinants were identified. Materials methods: cross-sectional 28...
Purpose: The relationship between personality traits and cardiovascular disease has gathered sustained interest over the last years, type –D (TDP) being significantly associated with coronary artery (CAD). However, data regarding connection TDP severity of CAD is scarce. aim our study was to assess complexity CAD, compare it other sociodemographic clinical features. Patients Methods: We conducted a cross-sectional case-control clinical-based on 221 consecutive hospitalized patients chest...
Objective Major depressive disorder (MDD) is a recurrent with an increasing incidence. Alterations in key signaling pathways of the nervous system, such as Wnt and MAPK pathways, mediated through microRNAs (miRNAs) provide crucial information regarding etiopathology MDD. We aimed to analyze whether heterogeneity literature findings differential expression miRNAs blood could arise from their different distributions among compartments. Methods performed pilot study analyzing miR-26a, miR-494,...
Background and objectives: Major depressive disorder (MDD) cardiovascular diseases (CVDs) represent serious prevalent medical conditions. Autonomic nervous system (ANS) dysfunctions, expressed by parameters of heart rate variability (HRV) turbulence (HRT), have been repeatedly associated with depression. The aim our study was to identify potential HRV HRT alterations in patients MDD, before after selective serotonin reuptake inhibitor (SSRI) therapy, observe any correlations between these...
Major depressive disorder (MDD) is a neuropsychiatric illness with an increasing incidence and shortfall of efficient diagnostic tools. Interview-based tools clinical examination often lead to misdiagnosis inefficient systematic treatment selection. Diagnostic monitoring biomarkers are warranted for MDD. Thus, the emerging field metabolomics promising tool capable portraying metabolic repertoire biomolecules from biological samples in minimally invasive fashion. Herein, we report untargeted...
Attention Deficit Hyperkinetic Disorder (ADHD) is a neurobiological behavioral disorder of the child, adolescent, and adult characterized by problems concentration, hyperactivity, impulsivity caused an imbalance chemical neurotransmitters in brain—dopamine noradrenaline. ADHD first-line drugs are divided psychostimulant, as Methylphenidate Amphetamines non-psychostimulant medications-Atomoxetine (the only representative medication approved our country children adolescents). The purpose...
COVID-19 has led to a global health crisis that is defining for our times and one of the greatest challenges emerge since World War II. The potential impact pandemic on mental should not be overlooked, especially among vulnerable populations such as women who gave birth during pandemic. study cross-sectional survey conducted from 1 March 2020 2023, period SARS-CoV-2 (COVID-19) pandemic, based retrospective evaluation 860 postpartum women. screening tool used assess symptoms depression was...
Perinatal depression (PPD) presents a significant public health concern, often influenced by psychological and personality factors. This study investigated the impact of traits, particularly neuroticism, obsessive-compulsive disorder (OCD) symptoms on severity PPD. The primary aim was to quantify contributions these factors risk PPD enhance early intervention strategies. A total 47 pregnant women with depressive per DSM-5 criteria at “Pius Brinzeu” County Emergency Hospital in Timisoara,...