A5050518399- Antibiotic Use and Resistance
- Patient Satisfaction in Healthcare
- Global Maternal and Child Health
- Advanced Drug Delivery Systems
- Pharmaceutical Practices and Patient Outcomes
- Healthcare professionals’ stress and burnout
- Innovations in Medical Education
- Global Health and Surgery
- Global Health Workforce Issues
- Online and Blended Learning
- Pharmaceutical studies and practices
- Analytical Methods in Pharmaceuticals
- COVID-19 Clinical Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 and Mental Health
- Advancements in Transdermal Drug Delivery
- Pregnancy and preeclampsia studies
- Evaluation of Teaching Practices
- Pharmaceutical Economics and Policy
- Long-Term Effects of COVID-19
- Inhalation and Respiratory Drug Delivery
- Drug Solubulity and Delivery Systems
- COVID-19 epidemiological studies
- Pharmaceutical Quality and Counterfeiting
- Phenothiazines and Benzothiazines Synthesis and Activities
University of Zambia
2016-2025
International Pharmaceutical Federation
2023
Africa Centres for Disease Control and Prevention
2023
Rhodes University
2016-2020
Introduction: There are increasing concerns with growing rates of antimicrobial resistance (AMR) across Africa, including in Zambia, enhanced by inappropriate utilization antibiotics the sectors. is a need hospitals to document current prescribing patterns via point prevalence surveys (PPS) alongside recognized indicators improve future use. The findings can subsequently be used develop and instigate appropriate stewardship programs (ASPs) quality Zambia. This includes encouraging ‘Access’...
Antimicrobial Stewardship Programs (ASPs) intended to optimize antibiotic use will be more effective if informed by the current status and patterns of utilisation. In Zambia's primary healthcare (PHC) settings, data on ASPs utilisation were inadequate guide improvements. As a first step, this study assessed prescribing ASP core elements among PHC first-level hospitals (FLHs) in Zambia. A point prevalence survey was conducted at five FLHs Lusaka using Global-PPS® protocol. Hospital evaluated...
Antimicrobial stewardship programmes (ASPs) aim to optimize antibiotic use and prevent antimicrobial resistance.
Background: Antimicrobial/Antibiotic Resistance (AMR) is among the major threats to global health. Due limited information on subject matter in Zambia, we assessed knowledge, attitude, and practices of community pharmacists AMR Antimicrobial Stewardship (AMS). Materials Methods: We conducted a descriptive cross-sectional study 144 randomly selected through structured questionnaire. Data were analysed using Statistical Package for Social Sciences version 22 at 95% confidence level. The...
Background: The novel coronavirus disease (COVID-19) is a serious global health problem that has negatively impacted the mental of students.Methods: We conducted an online descriptive cross-sectional study among 273 undergraduate pharmacy students at University Zambia from August to September 2020. A partial proportional odds regression model was used determine predictors anxiety. All statistical tests were set 95% confidence level (p<0.05).Results: response rate 70% obtained with...
The degradation of rifampicin (RIF) in an acidic medium to form 3-formyl rifamycin SV, a poorly absorbed compound, is accelerated the presence isoniazid, contributing poor bioavailability rifampicin. This manuscript presents novel approach which isoniazid formulated into gastric-resistant sustained-release microspheres and RIF microporous floating reduce potential for interaction between (INH) environment. Hydroxypropyl methylcellulose acetate succinate Eudragit® L100 polymers were used...
A needs-based approach is desirable for the transformation of pharmaceutical education, and to link education with health needs populations national priorities. There are varying levels data in literature on status all six World Health Organization (WHO) regions, especially context identification evidence-based policy interventions. The framework this study was FIP Development Goals.
Abstract Background Many countries are striving to become malaria-free, but global reduction in case estimates has stagnated recent years. Substandard and falsified medicines may contribute this lack of progress. Zambia aims eliminate their annual burden 1.2 million pediatric malaria cases 2500 child deaths due malaria. We examined the health economic impact poor-quality antimalarials Zambia. Methods An agent-based model, Falsified Antimalarial Research Impact (SAFARI), was modified applied...
Introduction: Sub-Saharan Africa and other low- middle-income countries (LMICs) have the highest rates of antimicrobial resistance (AMR) driven by high utilization. This is a concern as AMR appreciably increases morbidity, mortality costs. Pharmacogenetics (PGx) precision medicine are emerging approaches to combat AMR. Consequently, first step there need assess knowledge attitudes, PGx, among healthcare professionals use findings guide future interventions. Methodology: We conducted...
Introduction: urinary tract infections (UTIs) remain among significant causes of morbidity and mortality in pregnant women sub-Saharan Africa. Zambia shares this burden disproportionately compared to other countries it is unknown what extent HIV affects UTIs. This study investigated the prevalence UTIs associated factors infected attending antenatal care at a tertiary hospital Zambia.
Dissolution testing is a quality control tool used to assess batch-to-batch performance of dosage forms, thereby providing continued assurance product quality.Analytical methods for the assessment pharmaceutical must be validated according regulatory guidelines ensure that tests are reliable and valid.Agitation rate, mesh pore size, surfactant concentration, dissolution medium molarity experimental parameters may affect nevirapine (NVP) release were investigated optimized consistent,...
Abstract Background The novel coronavirus disease (COVID-19) is a serious global health problem that has negatively impacted the mental of students. Methods We conducted an online descriptive cross-sectional study among 273 undergraduate pharmacy students at University Zambia. A partial proportional odds regression model was used to determine predictors anxiety. All statistical tests were set 95% confidence level (p<0.05). Results response rate 70% obtained with majority being female...
Abstract Antibiotic resistance is among the major threats to global health. Due limited information on subject matter in Zambia, we assessed knowledge, attitude, and practices of community pharmacists antibiotic antimicrobial stewardship. We conducted a descriptive cross-sectional study 144 randomly selected through structured questionnaire. Data were analysed using Statistical Package for Social Sciences version 22 at 95% confidence level. A response rate 91% (n=144) was achieved. The...
Background: A significant number of patients suffering from hypertension, a major risk factor for cardiovascular morbidity, are said to access traditional medicine (TM) their disease management. Traditional medicine, originating indigenous knowledge that has been passed on generation generation, remained largely under-researched. There is paucity information the efficacy and toxicity these remedies. Indigenous systems (IKS) as utilised in healthcare provision primary care settings have...
Background: Despite continuing professional development (CPD) becoming a key strategy for improving health outcomes by enhancing the quality of pharmaceutical care services, CPD needs practitioners in Zambia remained unknown prior to this study. Aim: To determine and preferences among Zambia. Methods: This descriptive cross-sectional study involved administering structured self-administered online questionnaire collect data from 111 registered Results: The majority participants (80%) were...
Low job satisfaction levels among pharmacists are associated with poor motivation and performance in the workplace. However, Zambia, of remain unknown. Therefore, aim this article was to explore from public private health sectors Zambia.We conducted a cross-sectional study Zambian between April August 2019. We used previously validated self-administered questionnaire measure satisfaction. sent out 200 questionnaires, which 156 (78.0%) were returned. Bivariate analysis an adjusted general...
Ocimum americanum L. is an annual herbaceous plant used to manage pain and inflammation. Lack of standard dosage forms, safety efficacy data potentially exposes users this medicinal the risk toxic or sub-therapeutic effects, as well drug-herb interactions. The study developed a form containing O. extract assessed its anti-inflammatory stability. fusion method was formulate ointment comprising acetone extract, beeswax, soft-paraffin. Formulation optimization involved application Box-Behnken...
Despite snakebite antivenom being included on the WHO list of essential medicines, many parts world, especially Africa, lack effective and safe antivenoms.A descriptive, field-based, cross-sectional study was undertaken from August to November 2020 in 40 out 71 health facilities Ndola district. Interviews physical inspection were conducted at each facility.The revealed that only three (8%) all private had available time assessment. Factors significantly associated with supply central country...
Context: Newborns' low birth weight (LBW) has been linked to early infant morbidity and mortality. However, our understanding of the determinants outcomes LBW in this population is still poor. Aim: This study aimed assess among newborns at a tertiary hospital. Settings Design: Retrospective cohort Women Newborn Hospital Lusaka Zambia. Subjects Methods: We reviewed delivery case records neonatal files between January 1, 2018, September 30, 2019, for admitted intensive care unit. Statistical...
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