Rula M. Darwish

ORCID: 0000-0003-2359-676X
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About
Contact & Profiles
Research Areas
  • Pharmaceutical Practices and Patient Outcomes
  • Essential Oils and Antimicrobial Activity
  • Antibiotic Use and Resistance
  • Antifungal resistance and susceptibility
  • Innovations in Medical Education
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Antibiotic Resistance in Bacteria
  • Synthesis and Biological Evaluation
  • Antimicrobial Peptides and Activities
  • Vaccine Coverage and Hesitancy
  • Helicobacter pylori-related gastroenterology studies
  • SARS-CoV-2 and COVID-19 Research
  • Antimicrobial Resistance in Staphylococcus
  • Bone Tissue Engineering Materials
  • Bee Products Chemical Analysis
  • Cancer therapeutics and mechanisms
  • Respiratory and Cough-Related Research
  • Advanced biosensing and bioanalysis techniques
  • Medical Education and Admissions
  • Phytochemistry Medicinal Plant Applications
  • Biosensors and Analytical Detection
  • Biochemical and Structural Characterization
  • Oral health in cancer treatment
  • Complementary and Alternative Medicine Studies
  • Dental Implant Techniques and Outcomes

University of Jordan
2016-2025

Université Paris-Est Créteil
2024

Paris-Est Sup
2024

University of Technology - Iraq
2023

International Pharmaceutical Federation
2023

United States Agency for International Development
2023

King Abdulaziz University
2018-2021

University College London
1995-1997

King's College London
1995-1997

University of London
1995-1997

Factors associated with antibiotic use, resistance and safety have been well recognized worldwide in the literature. Nevertheless, only few studies conducted Jordan this area. The aim of study was to assess knowledge, behavior attitude toward antibiotics use among adult Jordanians. represents a cross sectional survey using an interviewer administered questionnaire. Data collected from random sample 1141 Jordanians, recruited at different settings, regarding their knowledge about...

10.1016/j.jsps.2011.11.005 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2011-12-07

Escherichia coli occurs naturally in the human gut; however, certain strains that can cause infections, are becoming resistant to antibiotics. Multidrug-resistant E. produce extended-spectrum β lactamases (ESBLs), such as CTX-M enzymes, have emerged within community setting an important of urinary tract infections (UTIs) and bloodstream may be associated with these community-onsets. This is first report testing antibiotic resistance-modifying activity nineteen Jordanian plants against...

10.1186/1472-6882-10-9 article EN cc-by BMC Complementary and Alternative Medicine 2010-02-28

To evaluate the effect of silver nanoparticles alone and in combination with Triclosan, trans-cinnamaldehyde against Staphylococcus aureus Escherichia coli biofilms on sutures to improve patients' outcomes.

10.1093/jambio/lxae063 article EN Journal of Applied Microbiology 2024-03-12

Background and Aim: Interest in plants with antimicrobial properties has been revived due to emerging problems associated using antibiotics eradicate Helicobacter pylori. Accordingly, this study aims assess the antibacterial effects of Punica granatum possible synergistic effect its extract along metronidazole against H. Materials Methods: Pomegranate peel ethanol extracts (PPEE) was tested a control strain pylori (NCTC 11916) vitro vivo female Wistar rats. Moreover, PPEE combination vitro....

10.14202/vetworld.2021.120-128 article EN cc-by Veterinary World 2021-01-01

Abstract Background The ongoing spread coronavirus disease worldwide has caused major disruptions and led to lockdowns. Everyday lifestyle changes antenatal care inaccessibility during the 2019 (COVID-19) pandemic have variable results that affect pregnancy outcomes. This study aimed assess alterations in stillbirth, neonatal-perinatal mortality, preterm birth, birth weight COVID-19 national lockdown. Methods We used data from Jordan stillbirths neonatal death surveillance system compare...

10.1186/s12884-021-04221-6 article EN cc-by BMC Pregnancy and Childbirth 2021-11-10

This study assesses Jordanian community pharmacists' readiness and willingness to deliver vaccination services in their practice sites. Between February April 2021, a self-administered online questionnaire was distributed via social media, WhatsApp messages, personal communication. The targeted practicing pharmacies. Descriptive inferential data analysis carried out. A total of 403 pharmacists participated the study. Almost 146 (36%) reported vaccinating patients However, assessment revealed...

10.1002/prp2.943 article EN cc-by Pharmacology Research & Perspectives 2022-03-03

Abstract Introduction Antimicrobial stewardship programs are intended to improve patient outcomes, reduce side effects, bacterial resistance, and costs. Thus, it is important assess their impact on an ongoing basis. We aimed the of antimicrobial program in two different hospitals which used approaches. Methodology This a retrospective observational study private [4088 records] Amman- Jordan. Antibiotic susceptibility using antibiogram results, consumption antibiotics Defined Daily Dose,...

10.1186/s12879-022-07906-1 article EN cc-by BMC Infectious Diseases 2022-12-07

The objective of this research was the preparation new 8-nitrofluoroquinolone models and investigation their antibacterial properties. work initially involved large scale synthon 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (3), followed by introduction substituted primary amine appendages at C-7 position to give derivatives 9a-g, in which amino group is appended benzenes or aromatic heterocycles, part a α-amino just simple aliphatic amine. This...

10.3390/12061240 article EN cc-by Molecules 2007-06-30

The purpose of this study was to evaluate the release chlorhexidine as an antifungal drug from doped self-cured poly (methyl methacrylate) (PMMA) acrylic resin and effect released on growth Candida albicans.Release evaluated using liquid chromatography, C. albicans investigated microbiologically a "well" technique Saboraud culture medium inoculated with resistant strain albicans.Chlorhexidine leached steadily out into distilled water at mouth temperature, sustained continued throughout...

10.2147/tcrm.s18297 article EN cc-by-nc Therapeutics and Clinical Risk Management 2011-06-01

Abstract Objectives Antibiotic usage has evolved over the years among Arab population, and it also gone under misuse resulting in development of antimicrobial resistance (AMR). Therefore, current study aimed to address this issue by evaluating level knowledge attitude population towards antibiotic AMR develop a pathway reduce risk resistance. Methods A cross-sectional was carried out including 11 countries from Middle East North Africa. validated translated questionnaire, consisting 34...

10.1093/jphsr/rmad014 article EN cc-by Journal of Pharmaceutical Health Services Research 2023-04-13

The study's aim was to explore academic entitlement among pharmacy students in different colleges the Arab World and assess associated factors.

10.1016/j.ajpe.2023.100640 article EN American Journal of Pharmaceutical Education 2024-01-04

The pharmacy profession has significantly changed over the years. Pharmacy students' perceptions of their coursework and future career aspirations may vary in relation to gender. present study explored motivations students enter school, satisfaction with academic program, plans after graduation, about Data were collected using a cross-sectional descriptive validated questionnaire built by research team. was conducted at twelve public private universities offering programs. In total, 918 have...

10.1371/journal.pone.0317896 article EN cc-by PLoS ONE 2025-03-03

Background Herbal and alternative medicine is increasingly used among cancer patients to manage disease, symptoms, improve quality of life. Reported usage rates worldwide vary from 3.5% 90%. Understanding prevalence predictors such use essential for safety efficacy, especially considering potential interactions with conventional treatments. Methods This cross-sectional study aimed evaluate the herbal in Jordan. All patients, including pediatric adult who can give consent or assent, were...

10.3389/fphar.2025.1535795 article EN cc-by Frontiers in Pharmacology 2025-05-15

(1) Background: Antimicrobial resistance represents an urgent health dilemma facing the global human population. The development of novel antimicrobial agents is needed to face rising number resistant bacteria. Ultrashort peptides (USAMPs) are considered promising that meet required criteria drug development. (2) Methods: Alapropoginine was rationally designed by incorporating arginine (R), biphenylalanine (B), and naproxen create ultrashort hexapeptide. activity alapropoginine evaluated...

10.3390/antibiotics10060712 article EN cc-by Antibiotics 2021-06-13

Background: Bacterial resistance is a challenging limitation in infection treatment. This work evaluates the potential antibacterial activity of conjugation Tryasine peptide with silver nanoparticles against selected pathogens. Materials and Methods: The was produced using three subunits tryptophan lysine amino acids, then its purity determined by reverse-phase high-performance liquid chromatography. confirmed mass spectrometry electrospray ionization spectrometry. Silver conjugate...

10.3390/antibiotics11081024 article EN cc-by Antibiotics 2022-07-30

A needs-based approach is desirable for the transformation of pharmaceutical education, and to link education with health needs populations national priorities. There are varying levels data in literature on status all six World Health Organization (WHO) regions, especially context identification evidence-based policy interventions. The framework this study was FIP Development Goals.

10.1016/j.rcsop.2023.100234 article EN cc-by-nc-nd Exploratory Research in Clinical and Social Pharmacy 2023-02-14
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