A5030677106- Advanced Proteomics Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Heat shock proteins research
- Peptidase Inhibition and Analysis
- Molecular Biology Techniques and Applications
- Chemotherapy-induced organ toxicity mitigation
- vaccines and immunoinformatics approaches
- Hibiscus Plant Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Virus-based gene therapy research
- Protease and Inhibitor Mechanisms
- Viral Infections and Immunology Research
- Magnetic properties of thin films
- Ubiquitin and proteasome pathways
- Pomegranate: compositions and health benefits
- Glutathione Transferases and Polymorphisms
- Endoplasmic Reticulum Stress and Disease
- Wnt/β-catenin signaling in development and cancer
- Connexins and lens biology
- Immunotherapy and Immune Responses
- Advanced Biosensing Techniques and Applications
- Edible Oils Quality and Analysis
- Cancer-related gene regulation
- Bladder and Urothelial Cancer Treatments
- RNA and protein synthesis mechanisms
University of Monastir
2007-2022
Institut Préparatoire aux Études d'Ingénieurs de Monastir
2012
Tunis El Manar University
2011
Tunis University
2011
Hôpital Charles-Nicolle
2011
The aim of this study was to investigate the phytochemical composition dried Roselle calyx (Hibiscus sabdariffa L.) using both ethanolic and aqueous extracts. We report antimicrobial activities against a wide range bacteria, yeast, fungi. antioxidant were tested 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl, 2-2'-azinobis-(3-ethylbenzthiazoline-6-sulfonic acid) radical scavenging assays. also for first time effect swarming motility in Pseudomonas aeruginosa PAO1. Our results showed that two...
Improvement of breast-cancer detection through the identification potential cancer biomarkers is considered as a promising strategy for effective assessment disease. The current study has used nonequilibrium pH gradient electrophoresis with subsequent analysis by mass spectrometry to identify protein alterations in invasive ductal carcinomas breast from Tunisian women. We have identified multiple tumor tissues that were picked, processed, and unambiguously assigned identities matrix-assisted...
This study aims to evaluate αB-crystallin expression in infiltrating ductal breast carcinomas (IDCAs), as well as, its prognostic significance. Using a two-dimensional electrophoresis matrix-assisted laser desorption/ionisation-time of flight mass spectrometry investigation coupled an immunohistochemical approach, we have assessed the IDCAs, other types tumors (invasive lobular carcinomas, medullary and situ carcinomas). Correlation between clinicopathological parameters cancer has also been...
The aim of this study was to evaluate calreticulin expression in infiltrating ductal breast carcinomas (IDCAs), as well its relationships with clinicopathological parameters the disease. Using a two-dimensional gel electrophoresis/matrix-assisted laser desorption ionization time flight mass spectrometry investigation coupled an immunohistochemical approach, we have assessed IDCAs, other types tumors. humoral immune response against estimated using serological proteomics-based strategy....
The aim of this study is to evaluate tropomyosin-4 (TM4) expression in infiltrating ductal breast carcinomas (IDCAs), as well its prognostic significance. Using a 2-DE/MALDI-TOF mass spectrometry investigation coupled with an immunohistochemical approach, we have assessed the TM4 IDCAs, other types tumors. Proteomic analyses revealed increased IDCA immunohistochemistry, overexpression was confirmed 51 additional tumor specimens. Statistical revealed, however, no significant correlations...
Breast cancer is the most diagnosed in women, accounting for approximately 40,000 deaths annually USA. In Tunisia, incidence of breast 19 new cases per 100,000 women year. Significant advances have been made areas detection and treatment, but a significant number cancers are detected late. The enormous progress proteomics, enabled by recent MS (mass spectrometry), has brought protein analysis back into limelight research, reviving old as well opening fields study like early detection,...
In this work, our aims were to investigate the antimicrobial resistance, and anti-quorum sensing activities of Punica granatum L. methanolic extract.Antibacterial antifungal performed against thirteen bacteria five fungal pathogens. Ultra-high performance liquid chromatography was used identify polyphenolic extract. The inhibition pyocyanin production, proteolytic elastolytic activity swarming motility in Pseudomonas aeruginosa PAO1 test strain estimated.The extract from P. dominated by...
Urotoxicity is a troublesome complication associated with cyclophosphamide (CP) and L-buthionine-SR-sulfoximine (BSO) treatment in chemotherapy. With this concern mind, the present study investigated potential effects of hydroxytyrosol extract from olive mill waste (OMW) on urotoxicity induced by acute CP BSO doses using Swiss albino mouse model. Toxicity modulation was evaluated measuring lipid peroxidation (LPO) antioxidants urinary bladder. The findings revealed that exerted protective...
Breast cancer is the most common malignancy in women, comprising about 18% of all female cancers. The important tools screening and early detection are imaging techniques: mammography, ultrasonography magnetic resonance imaging. However, up to 20% new breast incidents cannot be detected by these methods. Up now, poor diagnosis due a lack specific biomarkers. Therefore, there much interest identifying useful pathological markers that can help treatment this disease. Up detecting minor...