In order to establish if neuropsychiatric systemic lupus erythematosus (NPSLE) can be identified by any characteristic other than those used diagnose the (NP) disease itself, we retrospectively reviewed 98 (SLE) patients followed over a mean period of 10 years. NPSLE was in 22 patients. Stroke and generalized seizures were most frequent NP manifestations. The non-NPSLE groups similar with regard demographic characteristics, ACR criteria, serum autoantibodies, frequency hypertension...

Leprosy or Hansen's disease is a chronic granulomatous infectious caused by <i>Mycobacterium leprae</i> with high prevalence in some developing countries however, it rarely seen non-endemic regions. Arthritis has been described all types of disease. Chronic arthritis known to exist even paucibacillary forms, resolved treated and patients without reaction, suggesting perpetuated inflammatory process. In these cases leprosy can mimic autoimmune diseases such as rheumatoid arthritis. When...

Hand, foot, and mouth syndrome (HFMS) is a common acute illness. It characterized by mild clinical symptoms including fever, blisters, sores in the on palms soles following 3- to 7-day incubation period. This rarely seen adults. A 35-year-old male Caucasian patient had history of multiple episodes pharyngitis, hypertension, hypercholesterolemia, occasional abdominal pain. He presented with polyarthralgia knees hands odynophagia, followed oral mucosal aphthous lesions, vesicles soles. Three...

SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is a relatively rare entity. The therapeutic approach of patients with has included multiple drugs varying success incoherence responses. therapy still empirical today. commonly treated non-steroidal anti-inflammatory drugs, bisphophonates non-biologic disease modifying antirheumatic drugs. Recent reports showed successful treatment tumour necrosis factor α (TNF α) antagonists, but there dark side including subgroup...

Buerger9s disease or Thromboangiitis obliterans is a segmental inflammatory that affects the vessels and nerves of extremities. It usually men below 45 years old correlates with tobacco, as predisposing factor. The authors present case 34-year-old male, ulcers in fingertips progressive worsening: acrocyanosis, slow healing, necrosis finally loss substance. Dorsalis pedis posterior tibial pulses were not palpable. Personal history heavy smoking was (20 pack-years). angiography revealed...

Spondylodiscitis is an inflammatory disease, usually infectious, of one or more vertebral bodies and corresponding intervertebral discs. The fungal aetiology rare (less than 5% cases), affecting mostly immunocompromised individuals. It often a delayed diagnosis by the indolence symptoms, presenting itself as serious infection, which may result in important functional consequences. authors present case 75-year-old male, with constitutional complaints intense back pain. Prior recent history...

A 67-year-old woman of African origin with dermatomyositis, diagnosed 18 years before, and dystrophic calcification known for 5 years, presented at follow-up consultation fever, increased muscle weakness (scapular pelvic chains) gluteus pain, spontaneous purulent drainage. She was under cyclosporine 100 mg, prednisolone 10 mg biphosphonates (alendronic acid cholecalciferol). Physical examination revealed calcinosis universalis, lesions spread over the chin, forearms, hands, abdomen,...

Malignant lymphomas represent about 9% of cardiac neoplasms. Despite its life-threatening nature, the manifestations are often subclinical. In 20% deaths from lymphoma, involvement is found only in autopsy. The authors present case a 77-year-old female admitted due to intense back pain, vomiting, generalised pruritus, fatigue and weight loss. She had personal history hypertension breast cancer was noted 10 years before admission. thoracoabdominopelvic CT showed mass left atrium with...

The authors describe a first report of three types arthritis in the same patient: rheumatoid arthritis, psoriatic and gouty arthritis. A male patient, 56-year-old, Caucasian, with known history essential hypertension gout was presented. diagnosis made by isolation monosodium urate crystals synovial liquid when he 45-years-old. He diagnosed psoriasis 32-years-old, initially extensive cutaneous nail involvement (scalp, trunk limbs). Associated changes, had thickening both legs skin multiple...

We report a case of 65-year-old man with systemic lupus erythematosus (SLE) and antiphospholipid syndrome, presenting palpable purpuric lesions, necrotic blisters swelling ankles, after previous tracheobronchitis episode. Laboratory data were remarkable for mild proteinuria imaging studies normal. A skin biopsy showed IgA deposits on superficial dermal capillaries vasculitis (IgAV) (former Henoch-Schönlein purpura) was assumed. The patient treated colchicine, deflazacort azathioprine, but as...

Antiphospholipid syndrome (APS) is a systemic autoimmune disorder that characterised by the presence of antiphospholipid antibodies and common cause vascular thromboembolic phenomena. The management patients with APS currently directed to antithrombotic medications. international therapeutic guidelines recommend oral anticoagulation warfarin indefinitely after first thrombotic episode. However, lack for minority group – appropriately anticoagulated recurrent authors present clinical report...

Infective endocarditis can be associated with complex clinical presentations, sometimes a difficult multi-disciplinary management. <i>Actinobacillus actinomycetemcomitans</i> belongs to the <i>Haemophilus</i> species, <i>Actinomycetemcomitans</i>, <i>Cardiobacterium hominis</i>, <i>Eikenella corrodens</i> and <i>Kingella</i> species group, responsible for 5% 10% of infective in native heart valves. These organisms have slow fastidious growth pattern, often negative cultures, cause systemic...

A 32-year-old male patient presented with an acute polyarticular gout attack. Gout diagnosis was made 16 years before by isolation of monosodium urate crystals in synovial liquid. He had a frequency four to five attacks per year. Acute were treated non-steroidal anti-inflammatory drugs (ibuprofen) and colchicine. on no long-term medications. There family history gout. On examination he hypertensive (blood pressure 162/91 mm Hg) his body mass index normal, 19 kg/m2. important articular...

The report highlights the importance of strict clinico-histological correlations when skin biopsies are performed in diagnostic doubt systemic lupus erythematosus. Furthermore, PUVA is never indicated autoimmune conditions involving photosensitivity, due to high potential for internal and cutaneous aggravation disease, as authors observed this case.

Figure 1 (A, B)

Systemic sclerosis is a complex disorder that requires systematic screening. Our objective to report the European Scleroderma Trials and Research group centre affiliation its impact in our clinical practice.The process, database update current patient evaluation, with respect demographic features. Cumulative mortality was analysed.We identified 19 female patients (which met all American College of Rheumatology/ League Against Rheumatism 2013 criteria for systemic sclerosis) under follow-up,...