A5023944809- Olfactory and Sensory Function Studies
- Neurobiology and Insect Physiology Research
- Insect Utilization and Effects
- Biochemical Analysis and Sensing Techniques
- Control Systems and Identification
- Extremum Seeking Control Systems
- Plant and animal studies
- Advanced Chemical Sensor Technologies
- Process Optimization and Integration
- Essential Oils and Antimicrobial Activity
- Fermentation and Sensory Analysis
- Heat Transfer and Mathematical Modeling
Leibniz-Institute for Food Systems Biology at the Technical University of Munich
2017-2024
Technical University of Munich
2002-2024
Hungarian Academy of Sciences
1972
The assignment of cognate odorant/agonist pairs is a prerequisite for an understanding odorant coding at the receptor level. However, identification new ligands receptors (ORs) in cell-based assays has been challenging, due to their individual and rather sub-optimal plasma membrane expression, as compared with other G protein-coupled receptors. Accessory proteins, such chaperone RTP1S, or Ric8b, have improved surface expression least portion ORs. Typically, recombinant ORs carry N-terminal...
Geosmin, a ubiquitous volatile sesquiterpenoid of microbiological origin, is causative for deteriorating the quality many foods, beverages, and drinking water, by eliciting an undesirable "earthy/musty" off-flavor. Moreover, across species from worm to human, geosmin volatile, chemosensory trigger both avoidance attraction behaviors, suggesting its role as semiochemical. Volatiles typically are detected receptors nose, which have evolved best detect ecologically relevant food-related...
4-Methylphenol is a food-related odor-active volatile with high recognition factor, due to its horse stable-like, fecal odor quality. Its ambivalent hedonic impact as key aroma compound, malodor, and semiochemical has spurred the search for cognate, chemosensory odorant receptors across species. A human receptor highly characteristic 4-methylphenol been elusive. Here, we identified characterized OR9Q2 be tuned purified 4-methylphenol, but not contaminant isomer 3-methylphenol. This selective...
Grapevine (Vitis vinifera) is one of the most important perennial fruit plants. The variety Riesling stands out by developing a characteristic petrol-like odor note during aging, elicited aroma compound 1,1,6-trimethyl-1,2-dihydronaphthalene (TDN). UV-dependent TDN contents differ largely among Rieslings grown in northern versus southern hemisphere. Highest concentrations were found Australian Rieslings, where scoring ingredient. In contrast, from Europe, for example, may be tending cause...
All living things speak chemistry. The challenge is to reveal the vocabulary, odorants that enable communication across phylogenies and translate them physiological, behavioral, ecological function. Olfactory receptors (ORs) interface animals with airborne odorants. Expression in heterologous cells makes it possible interrogate single ORs identify cognate ligands. cosmopolitan, anthropophilic strain of vinegar fly Drosophila melanogaster depends on human resources housing for survival....
Abstract Background All living things speak chemical. The challenge is to discover the vocabulary, volatile odorant chemicals that enable communication across phylogenies and translate them physiological, behavioural ecological function. Olfactory receptors (ORs) interface animals with airborne odorants. Expression of single ORs in human embryonic kidney cells (HEK-293) makes it possible interrogate synthetic identify cognate ligands convey olfactory information. Results cosmopolitan strain...
All living things speak chemical. The challenge is to reveal the vocabulary, volatile odorant chemicals that enable communication across phylogenies and translate them physiological, behavioural ecological function. Olfactory receptors (ORs) interface animals with airborne odorants. Expression in heterologous cells makes it possible interrogate single ORs synthetic identify cognate ligands. cosmopolitan strain of vinegar fly Drosophila melanogaster has accompanied human expansion out Africa....