A5079686738- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
- Salivary Gland Disorders and Functions
- Respiratory Support and Mechanisms
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Foreign Body Medical Cases
- Olfactory and Sensory Function Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Obstructive Sleep Apnea Research
- Psychosomatic Disorders and Their Treatments
- Neurogenetic and Muscular Disorders Research
- Anesthesia and Neurotoxicity Research
- Cleft Lip and Palate Research
- Metastasis and carcinoma case studies
- Congenital heart defects research
- Lung Cancer Research Studies
- Head and Neck Surgical Oncology
- Oxidative Organic Chemistry Reactions
- Pressure Ulcer Prevention and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Genetics and Neurodevelopmental Disorders
- Genomic variations and chromosomal abnormalities
Aichi Gakuin University
2017-2025
Nagoya City University
2005-2024
Nagoya University
2019-2024
Kobe College
2024
Tohoku University
2013-2023
Nanzan University
2023
Toyokawa City Hospital
2022
Nagoya University Hospital
2019
Satou Hospital
2019
Toho University
2019
Abstract Previous reports have shown that during chronic inflammation, the tryptophan (TRP)-kynurenine (KYN) pathway plays a pivotal role in onset of depression. The aim this study was to investigate characteristics serum TRP-KYN metabolite profile high-risk subjects major depressive disorder (HRMDD) defined by depression scores. concentrations metabolites {TRP, KYN, 3-hydroxyanthranilic acid (3HAA), 3-hydroxykynurenine (3HK), kynurenic (KYNA) and anthranilic (AA)} were assessed from HRMDD,...
Introduction Food questionnaire surveys are often used to evaluate masticatory function. In daily clinical practice in Japan, a survey is performed using list of food groups suitable for the Japanese diet. The foods on were categorized into five based their mastication index. patient's function determined by that can be eaten. index, which indicates chewability, was defined percentage 110 denture wearers who responded they could eat normally. A with this useful because its simplicity;...
Abstract Chronic orofacial pain (COP) is relieved by duloxetine (DLX) and frequently causes depressive symptoms. The aim of this study was to confirm effects DLX on symptoms, associate with their effectiveness in platelet serotonin transporter (SERT) expression, which a target molecule plasma concentration COP patients We assessed for the severity symptoms using Visual Analog Scale (VAS) 17-item Hamilton Depression Rating (HDRS), respectively. were classified into 2 groups based HDRS before...
We appreciate your thoughtful feedback regarding our case report on facioscapulohumeral muscular dystrophy (FSS). fully understand the importance of accuracy in medical literature and concern spread potentially inaccurate information. As we emphasized previous response, followed best practices treatment a patient who had already been diagnosed with FSS by another physician, stand validity as presented. selecting appropriate accurate references when preparing report. Our intention was to rely...
Nasotracheal intubation (NTI) is widely used in dental and maxillofacial surgeries to secure the airway while maintaining an unobstructed surgical field. However, NTI associated with complications such as nasal bleeding, bacteremia, retropharyngeal perforation. Among these, medical device-related pressure injuries (MDRPIs) caused by nasotracheal tubes are a significant concern. These range from erythema severe necrosis can lead postoperative pain, aesthetic concerns, prolonged treatment. 3M...
Patients with small cell carcinoma of the esophagus have a poor prognosis and generally been treated by chemotherapy. However, all reported cases were at advanced stages. We need to establish an adequate treatment for patients invasion limited submucosal layer. In this paper, five carcinomas, which accounted 2.8% 180 surgically esophageal reviewed pathological findings, treatment, outcome. Among three who had layer, two survived 7 9 years after surgery no evidence disease. One them was using...
McGrath MAC video laryngoscope offers excellent laryngosopic views and increases the success rate of orotracheal intubation in some cases. The aim this study was to determine usefulness for routine nasotracheal by comparing with Airway scope Macintosh laryngoscope. A total 60 adult patients ASA physical status class 1 or 2, aged 20–70 years were enrolled study. Patients scheduled elective oral surgery under general anesthesia intubation. Exclusion criteria included lack consent expected...
Burning mouth syndrome (BMS) and atypical odontalgia (AO) are examples of somatic symptom disorders with predominant pain around the orofacial region. Neuroinflammation is thought to play a role in mechanisms, but few studies have been conducted. We aimed better understand neuroinflammation pathophysiology treatment BMS/AO.Plasma levels 28 neuroinflammation-related molecules were determined 44 controls 48 BMS/AO patients both pretreatment 12-week post-treatment duloxetine.Baseline plasma...
Patients with small cell carcinoma of the esophagus have a poor prognosis and generally been treated by chemotherapy. However, all reported cases were at advanced stages. We need to establish an adequate treatment for patients invasion limited submucosal layer. In this paper, five carcinomas, which accounted 2.8% 180 surgically esophageal reviewed pathological findings, treatment, outcome. Among three who had layer, two survived 7 9 years after surgery no evidence disease. One them was using...
Nasotracheal intubation can potentially result in microbial contamination from the upper respiratory tract to lower tracts. However, an ideal nasotracheal disinfection method is yet be determined. Therefore, we compared effects between benzalkonium chloride and povidone iodine intubation. Overall, this study enrolled 53 patients aged 20–70 years who were classified into classes 1 2 as per American Society of Anesthesiologists-physical status scheduled undergo general anesthesia with NTI....
While anaphylaxis can occur at any time during general anesthesia, 90% of cases induction anesthesia. As several drugs are administered simultaneously this time, it is difficult to identify the causative agent. However, has been found that rocuronium most common drug associated with perioperative anaphylaxis. We treated 2 patients who were sugammadex for anaphylactic symptoms thought be caused by rocuronium, after which disappeared. One important aspects treating shock improving...
Abstract In the anesthetic management in this case was how to manage patient without causing respiratory depression and muscle fatigue.
Abstract Background Postoperative hoarseness after general anesthesia is associated with patient discomfort and dissatisfaction. A recent large retrospective study showed that single-lumen endotracheal tube intubation by a trainee did not alter the incidence of postoperative pharyngeal symptoms compared senior anesthesiologist. However, there limited information about relationship between anesthesiologist’s experience double-lumen intubation. We tested hypothesis performed increases to...
Abstract. This study evaluates the effects of climate change on economic losses due to flood-related damage in Japan. Three selected GCM data were downscaled using an analytical method that uses observed precipitation as reference resolution. The used estimate extreme rainfall for different return periods. estimates then entered into a two-dimensional (2-D) non-uniform flow model flood inundation information. A novel technique based land use type area was employed damage. results analysis...
In spite of improvements in surgical technique and perioperative care, severe lung complication remains as the leading cause morbidity thoracic esophageal cancer patients who undergo esophagectomy. The purpose this study was to evaluate safety effectiveness postoperative drug therapy using low dose dopamine, gabexate mesilate, ulinastatin on patients. Sixty-one operated for from 1996 2000 were treated postoperatively with dopamine (300 microg/kg/h), mesilate (80 mg/h), 000 unit/day) a group....
Abstract Objective The aim of this study was evaluation the association between severity pain and expression total or ubiquitinated serotonin transporter (SERT) protein in patients with burning mouth syndrome atypical odontalgia (BMS/AO), who were treated by duloxetine. Methods Patients BMS/AO assessed for using visual analog scale (VAS), SERT platelets before (baseline) 12 weeks after duloxetine‐treatment. Results at baseline all ( n = 33) higher lower, respectively, compared to those...
Abstract Background Nasal bleeding is the most common complication during nasotracheal intubation (NTI). To reduce nasal bleeding, mucosa treated with vasoconstrictors (epinephrine [E] or tramazoline [T]) prior to NTI. This study aimed determine whether E T more effective and safe for reducing Methods was preregistered on UMIN-CTR after being approved by IRB of School Dentistry at Aichi Gakuin University. Written consent received from all patients. Total 206 patients aged 20–70 years...
Background: 3M microfoam™ surgical tape (3ST: Japan Limited) is used for pressure wound control of medical equipment. It cushioned and can be fitted to any body part. Here we investigated whether 3ST prevents nasal injury associated with nasotracheal intubation (NTI). Methods: We conducted a prospective, randomized double-blind study, enrolling 63 patients aged 20 70 years, who underwent general anesthesia NTI. They were divided into 2 groups; those treated (group S ; n = 31) C 31). After...
Stabilization of circulatory dynamics is a critical issue in the anesthetic management patients with hypertrophic cardiomyopathy (HCM). In this report, we managed general anesthesia for 74-year-old male patient nonobstructive HCM who developed instability intraoperatively. Severe bradycardia measuring 35 beats/min and hypotension 78 mm Hg systolic were observed during surgery. Using stroke volume variation from FloTrac as indices, successful was performed dopamine. The thought to be result...
Various questionnaires have been validated as methods for screening of neuropathic pain, but none established the orofacial region. Although chronic pain and depression are likely to comorbid, few studies examined relationship between depression. Therefore, we evaluated potential Japanese Version PainDETECT an assessment tool associated with burning mouth syndrome (BMS) persistent idiopathic facial (PIFP). We also scale such Beck's Depression Inventory (BDI: a subjective index) Hamilton...
Freeman-Sheldon syndrome (FSS) is characterized by multiple joint contractures, characteristic facial features, such as microtia, defects of the hands and feet, clubfoot, skeletal malformations. This report illustrates case a patient with FSS who was managed under local anesthesia intravenous sedation for oral surgery.
Rocuronium bromide (RB) is known to cause vascular pain. Although there have been a few reports that diluted administration causes less pain, no studies investigating and the onset time of muscle relaxation. Therefore, we examined influence RB on relaxation 39 patients were randomly assigned three groups: stock solution 10 mg/ml (Group 1), two-fold dilution 5 2), or three-fold 3.3 3). After largest vein forearm was secured, anesthesia induced by propofol 0.6 mg/kg administered. The...