A5037861936- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- RNA modifications and cancer
- Mycobacterium research and diagnosis
- Studies on Chitinases and Chitosanases
- melanin and skin pigmentation
- Liver Disease Diagnosis and Treatment
- Molecular Biology Techniques and Applications
- Hedgehog Signaling Pathway Studies
- Antibiotic Use and Resistance
- RNA Research and Splicing
- Multiple Myeloma Research and Treatments
- Axon Guidance and Neuronal Signaling
- Complementary and Alternative Medicine Studies
- Cytokine Signaling Pathways and Interactions
- ATP Synthase and ATPases Research
- Ion Transport and Channel Regulation
- Chemokine receptors and signaling
- Quality and Safety in Healthcare
- Hair Growth and Disorders
- Vibrio bacteria research studies
- Chronic Kidney Disease and Diabetes
- Urinary Bladder and Prostate Research
- Herpesvirus Infections and Treatments
Taibah University
2021-2025
Menoufia University
2018-2024
Benha University
2018-2021
Background: The prevalence of opportunistic bacterial infections poses a significant challenge in healthcare facilities worldwide, including Saudi Arabia. These are often associated with increased morbidity and mortality, particularly vulnerable populations such as intensive care unit (ICU) patients. This study was conducted to characterize the strains that prevalent settings across By identifying these their phylogenetic relationships, aims enhance understanding diversity environments...
Background and Aim: Diabetes mellitus (DM) is a chronic disorder with diabetic retinopathy (DR) as one of its main microvascular outcomes, being prime cause vision loss. Dysregulation microRNAs (miRNAs) has been associated some complications such retinopathy. This hypothesised changes in the serum miR-93 miR-152 diabetes Methods: The study cohort consisted 80 healthy volunteers, type 2 patients, whom 40 had proliferative (PDR) non-proliferative (NPDR). Serum fasting 2-hour postprandial...
We aimed to evaluate the diagnostic roles of AFAP1-AS1 and ASB16-AS1 in colorectal cancer highlight their predicting patients' prognosis.In this case-control study, 146 participants were involved. Group I included 47 patients with CRC. II composed 49 benign lesions colon, III 50 apparently normal subjects coincided age gender as controls. All subjected clinical endoscopic evaluations, CA19-9, CEA, quantification relative expression lncRNAs AFAP1-AS1.CRC had significantly elevated levels both...
Schizophrenia is a serious, complex mental disorder. The impairment of oxidative phosphorylation has detrimental consequence on CNS function. Different ATP synthase subunits have been involved in the pathological process various neurodegenerative disorders. Our goal was to evaluate mRNA expression level membrane subunit c locus 1 (ATP5G1, also named ATP5MC1) gene patients with schizophrenia.Determination levels ATP5G1 plasma and peripheral blood mononuclear cells (PBMCs) were performed by...
Background and Aim: Diabetic nephropathy (DN) is a major determinant of end-stage renal disease (ESRD). Altered microRNA levels lead to serious chronic diseases, such as diabetes. We aimed measure the expression two microRNAs, microRNA126 192 in DN investigate their connection with albuminuria levels. Methods: This study included 229 subjects (134 patients 95 controls). Serum lipid profiles, glucose levels, glycated haemoglobin (HbA1c) functions were assayed. The microRNA192 determined by...
Increasing interest has been focused on lncRNAs as potential markers in the pathogenesis and progression of numerous diseases.We aimed to investigate expression pattern role cell-free (GAS5, HCG27_201 LY86-AS1) pre-diabetic, diabetic T2DM groups.Quantification level was performed by real-time PCR 210 individuals classified (T2DM), pre-diabetic control groups.Significant differences were observed relative LY86-AS1 HCG27_201) among three studied groups. The LncRNA levels decreased gradually...
Genetic factors are vital participants in the development and progression of myocardial infarction (MI). Adiponectin has been assumed to have a protective role MI adiponectin receptors variants could be determinant for atherosclerosis. We aimed evaluate prevalence ADIPOQ (rs2241766) ADIPOR2 (rs10773989) polymorphisms their association with mRNA levels circulatory patients MI.A total 220 were classified into two groups: group 1 included 120 MI, 2 involved 100 healthy as controls. Genotyping...
Introduction:Operating room nurses ( ORN) are exposed to various hazards in operating rooms (ORs) which can affect their health.Aim of work: To identify potential occupational the OR , assess risk adverse health effects among (ORN) related these and recommend prevention control measures protect them .Materials methods: This cross-sectional study targeted all staff working ORs Benha University Hospitals, Qualubeyia Governorate, Egypt.Data were collected using an interview questionnaire...
Hepatocellular carcinoma (HCC) is a major health burden globally. Dysregulation of miRNA 148a-3p engaged in carcinogenesis. TGF-β profibrogenic cytokine. This study assesses the expression level and its relationship with serum TGF-β1 fibrosis index based on four factors (FIB-4) Egyptian patients HCV-associated HCC.
Epigenetic modifications is very crucial in managing on/off switch of the genes, and kind cell that being built. The specific goals this study are to identify role histone modifications, DNA methylation, their interaction with each other on gene expression according ChIP-Seq, RNA-Seq, bisulfite sequencing results. Therefore, order offer wide profound analysis we went specify strains for regulatory components, describe molecular events, contemplate concerning potential clinical utility....
Background Noncoding RNAs have recently proven their contributing role in the pathogenesis of numerous diseases. The etiology psoriasis is still not well defined, and genetic environmental factors are blamed. We meant to explore association circRNAs/microRNAs inspect correlation with clinical features disease.
Background The majority of acute myeloid leukemia (AML) patients respond to initial chemotherapy, but only a minority cases achieves long-term survival. Renin, as part the renin–angiotensin system, is directly linked activities hematopoietic cytokines during normal hematopoiesis and in myeloproliferative neoplasms. In some hematological malignancies, blast cells have been observed express renin, which not found marrow.Aim aim this was study expression renin gene prognostic marker...
According to the World Health Organization (WHO), definition of infertility is 'the inability a sexually active, non-contracepting couple achieve spontaneous pregnancy in one year. The category 'unexplained male infertility' (UMI) reserved for infertile men with unknown origin normal semen and which female factors have been ruled out. Some cases unexplained could be due IR, leading hypogonadism other metabolic features. To evaluate serum level irisin patients idiopathic infertility. Serum...