- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Hemodynamic Monitoring and Therapy
- Hepatocellular Carcinoma Treatment and Prognosis
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Soil erosion and sediment transport
- Dental Radiography and Imaging
- Radiopharmaceutical Chemistry and Applications
- Organ Transplantation Techniques and Outcomes
- Radioactive contamination and transfer
- Reconstructive Surgery and Microvascular Techniques
- Liver Disease and Transplantation
- Pancreatic and Hepatic Oncology Research
- Nuclear Physics and Applications
- Digital Radiography and Breast Imaging
- Advanced Radiotherapy Techniques
- Advanced MRI Techniques and Applications
- Nuclear Materials and Properties
- Polymer Nanocomposite Synthesis and Irradiation
- Ultrasound Imaging and Elastography
The University of Texas MD Anderson Cancer Center
2017-2025
University of Alabama at Birmingham
2025
NYU Langone Health
2024
The University of Texas Health Science Center at Houston
2018-2019
The University of Texas Southwestern Medical Center
2019
The Ohio State University
2009-2016
The Ohio State University Wexner Medical Center
2016
Columbus Center
2009
University of Chicago
2002
John Carroll University
2000-2001
In x‐ray computed tomography (CT), materials with different elemental compositions can have identical CT number values, depending on the mass density of each material and energy detected beam. Differentiating classifying tissue types contrast agents thus be extremely challenging. multienergy CT, one or more additional attenuation measurements are obtained at a second, third energy. This allows differentiation least two materials. Commercial dual‐energy systems (only measurements) now...
Abstract Radiomics has shown promise in improving models for predicting patient outcomes. However, to maximize the information gain of radiomics features, especially larger cohorts, variability features owing differences between scanners and scanning protocols must be accounted for. To this aim, imaging feature values was evaluated on 100 computed tomography at 35 clinics by a phantom using controlled protocol commonly used chest head local clinic. We linear mixed-effects model determine...
Background Assessments of the quantitative limitations among six commercially available dual-energy (DE) CT acquisition schemes used by major manufacturers could aid researchers looking to use iodine quantification as an imaging biomarker. Purpose To determine limits detection and DE in phantoms comparing rapid peak kilovoltage switching, dual-source, split-filter, dual-layer detector systems different scanners. Materials Methods Seven 50-mL iohexol solutions were used, with concentrations...
Radiomics studies require many patients in order to power them, thus are often combined from different institutions and using imaging protocols. Various have shown that protocols affect radiomics feature values. We examined whether data cohorts with controlled improved patient outcome models. retrospectively reviewed 726 CT 686 PET images head neck cancer patients, who were divided into training or independent testing cohorts. For each patient, features preprocessing calculated two clinical...
To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy treatment planning that combines deep-learning(DL) aperture predictions and forward-planning algorithms. We designed algorithm to automate the clinical with field-in-field. DL models were trained, validated, tested on 555 patients automatically generate shapes primary boost fields. Network inputs digitally reconstructed radiography, gross tumor volume(GTV), nodal GTV. A physician scored each 20 a...
The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and practice medical physics. AAPM has more than 8,000 members principal organization physicists United States. will periodically define new guidelines for physics help science improve quality service patients throughout Existing be reviewed purpose revision or renewal, as appropriate, on their fifth anniversary sooner. Each guideline...
Abstract Background Variation in imaging protocol, patient positioning, and the presence of artifacts can vary image quality CT images used for radiotherapy planning. Automated methods spatial resolution (SR) estimation exist but require further investigation validation wider adoption. Purpose To validated previously existing algorithm SR introduce improvements that make it robust to site, artifacts. Method A reference based on previous gold standard was recreated modified improve...
Existing natural latex radiation-attenuating gloves (RAGs) contain a high loading of radiation attenuation filler that reduces their mechanical properties to below Food and Drug Administration (FDA) medical glove requirements. RAGs are commonly formulated using Hevea rubber lead-based fillers. The former can cause life-threatening allergic responses the latter known for toxicity. In this work, new lead-free RAG formulation based on circumallergenic guayule (GNRL) non-toxic bismuth trioxide...
Inferior vena cava filters (IVCFs) constructed with poly-p-dioxanone (PPDO) are promising alternatives to metallic and their associated risks complications. Incorporating high-Z nanoparticles (NPs) improves PPDO IVCFs' radiopacity without adversely affecting safety or performance. However, increased from these studies insufficient for filter visualization during fluoroscopy-guided IVCF deployment. This study focuses on the use of bismuth (BiNPs) as radiopacifiers render sufficient signal...
Purpose Material differentiation has been made possible using dual‐energy computed tomography (DECT), in which the unique, energy‐dependent attenuating characteristics of materials can provide new diagnostic information. One promising application is clinical integration biodegradable polymers as temporary implantable medical devices impregnated with high‐atomic number (high‐Z) materials. The purpose this study was to explore incorporation high atomic contrast a bioresorbable inferior vena...
AuNP infusion significantly improved absorbable IVCF's visualization in CT for device monitoring and clot trapping ability with no adverse effects.
The downslope transport of rare earth element-tagged soil particles remobilized during a spring thunderstorm was studied on both natural prairie and an agricultural field in southwestern Iowa (U.S.A.). A technique developed for tagging soils with the elements Eu, Tb, Ho to ∼1000 ppm via coprecipitation MnO2. Tagged material replaced target locations; surficial samples were collected following precipitation runoff; element concentrations determined by inductively coupled plasma mass...
Radiomics studies require large patient cohorts, which often include patients imaged using different imaging protocols. We aimed to determine the impact of variability in protocol parameters and interscanner a phantom that produced feature values similar those patients. Positron emission tomography (PET) scans Hoffman brain were acquired on GE Discovery 710, Siemens mCT, Philips Vereos scanners. A standard-protocol scan was each machine, then parameter could be changed altered individually....
Abstract Purpose The purpose of this work was to estimate and compare breast lung doses chest CT scans using organ‐based tube current modulation (OBTCM) those from conventional, attenuation‐based automatic (ATCM) across a range patient sizes. Methods Thirty‐four patients (17 females, 17 males) who underwent clinically indicated chest/abdomen/pelvis (CAP) examinations employing OBTCM were collected two multi‐detector row scanners. Patient size metric assessed as water equivalent diameter ( D...
Naturally occurring radioactive material consists of 238U, 235U and 232Th series daughters; it is released into the environment from many anthropogenic sources. The use quadrupole ICP-MS well-suited to site investigations releases naturally through measurements ratios 232Th∶230Th, 230Th∶238U 234U∶238U. Each ratio measurement may potentially indicate contrast between geochemical background affected environment. 232Th∶230Th was measured in samples prepared by fusion or selective extraction; Th...
Abstract Purpose Routine quality assurance (QA) testing to identify malfunctions in medical imaging devices is a standard practice and plays an important role meeting standards. However, current daily computed tomography (CT) QA techniques have proven be inadequate for the detection of subtle artifacts on scans. Therefore, we investigated ability radiomics phantom detect not detected conventional QA. Methods An updated credence cartridge was used this study, with focus two cartridges (rubber...
Purpose Assessment of image quality directly in clinical data is an important control objective as phantom‐based testing does not fully represent across patient variation. Computer algorithms for automatically measuring noise computed tomography (CT) images have been introduced, but the accuracy these unclear. This work benchmarks global (GN) algorithm automatic measurement contrast‐enhanced abdomen CT exams comparison to precise reference measurements. The GN was further optimized compared...