- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Anatomy and Medical Technology
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Breast Cancer Treatment Studies
- Nonmelanoma Skin Cancer Studies
- Semiconductor Quantum Structures and Devices
- Quantum and electron transport phenomena
- Breast Implant and Reconstruction
- Multi-Agent Systems and Negotiation
- Manufacturing Process and Optimization
- Magnetic properties of thin films
- Model-Driven Software Engineering Techniques
- Digital Radiography and Breast Imaging
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Advances in Oncology and Radiotherapy
- Advanced X-ray Imaging Techniques
- Service-Oriented Architecture and Web Services
- Radiomics and Machine Learning in Medical Imaging
- Robotic Path Planning Algorithms
- Cutaneous Melanoma Detection and Management
- Robotic Mechanisms and Dynamics
- Reconstructive Surgery and Microvascular Techniques
Minnesota Oncology
2024
Mayo Clinic Hospital
2020
The University of Texas MD Anderson Cancer Center
2015-2019
The University of Texas Health Science Center at Houston
2018-2019
University of Houston
2018
Massachusetts General Hospital
2012-2018
Harvard University
2018
RAND Corporation
2015
Idaho State University
2015
The University of Texas at Austin
2015
Using 3D printing to fabricate patient-specific devices such as tissue compensators, boluses, and phantoms is inexpensive relatively simple. However, most materials have not been well characterized, including their radiologic equivalence. The purposes of this study were (a) determine the variance in Hounsfield Units (HU) for printed objects, (b) if HU varies over time, (c) calculate clinical dose uncertainty caused by these material variations.For a sample 10 blocks each PLA, NinjaFlex, ABS,...
Abstract Purpose Patient‐specific 3D‐printed phantoms have many potential applications, both research and clinical. However, they been limited in size complexity because of the small most commercially available 3D printers as well material warping concerns. We aimed to overcome these limitations by developing testing an effective printing workflow fabricate a large patient‐specific radiotherapy phantom with minimal errors. In doing so, we produced full‐scale real postmastectomy patient....
Abstract Purpose The goal of total scalp irradiation ( TSI ) is to deliver a uniform dose the scalp, which requires use bolus cap. Most current methods for fabricating caps are laborious, yet still result in nonconformity and low reproducibility, can lead nonuniform scalp. We developed validated patient‐specific using three‐dimensional (3D) printing. Methods materials 3D‐printing were radiologically analyzed identify material with properties suitable as A Python script was within commercial...
Background and purposePostmastectomy radiotherapy (PMRT) is complex to plan deliver, but could be improved with 3D-printed, patient-specific electron tissue compensators. The purposes of this study were develop an algorithm design compensators that achieve clinical goals, 3D-print the planned compensators, validate calculated dose distributions film thermoluminescent dosimeter (TLD) measurements in 3D-printed phantoms PMRT patients.Materials methodsAn iterative was developed corresponding...
Purpose: To demonstrate the first instance of direct production deliverable plans using multi‐objective IMRT treatment planning. Method and Materials: Three clinical cases are studied: a pancreas, prostate, brain. The research software ORBIT Workstation is used to create database Pareto optimal plans. For each case, N+1 generated, where N number objective functions. N=6, 8, 9 for brain, respectively. anchor points solutions (each individually minimized) single equally weighted solution. all...
We have measured T1 spin lifetimes of a 14 nm modulation-doped (100) GaAs quantum well using time-resolved pump-probe Kerr rotation technique. The was selected by tuning the wavelength probe laser. in excess 1 μs were at 1.5 K and 5.5 T, exceeding typical T2* that been II-VI wells orders magnitude. observed effects from nuclear polarization, which largely removable simultaneous magnetic resonance, along with two distinct under some conditions likely result probing differently localized...
Purpose: To test the feasibility of using 3D-printed patient-specific phantoms for intensity-modulated radiation therapy (IMRT) quality assurance (QA). Methods: We created a whole-head phantom 3D printer. The printer data file was from high-resolution DICOM computed tomography (CT) images 3-year old child treated at our institution medulloblastoma. A custom-modified extruder system used to create tissue-equivalent materials. For printing process, Hounsfield Units CT were converted...
Purpose: This work investigated the proton tissue‐equivalence of various 3D printed materials. Methods: Three printers were used to create 5 cm cubic phantoms made different plastics with varying percentages infill. White resin, polylactic acid (PLA), and NinjaFlex used. The infills ranged from 15% 100%. Each phantom was scanned a CT scanner obtain HU value. relative linear stopping power (RLSP) then determined using multi‐layer ion chamber in 200 MeV beam. RLSP measured both parallel...
To develop a VMAT optimization procedure using information from Multi-Criteria Optimization of IMRT plans and to perform treatment planning comparison for prostate cancer patients.IMRT (MCO), 6 MV photons, 20 7 fields were generated 10 patients in the RayStation system (Version 2.2.13, Raysearch Laboratories, Stockholm, Sweden). The prescription dose was 7560 cGy PTV 5796 seminal vesicles, simultaneous integrated boost technique. resulting DVH parameters field IMRT-MCO plan used as initial...
Purpose: Patient‐specific tissue equivalent compensators can be used for post‐mastectomy radiation therapy (PMRT) to achieve homogenous dose distributions with single‐field treatments. However, current fabrication methods are time consuming and expensive. 3D‐printing technology could overcome these limitations. The purposes of this study were [1] evaluate materials 3D‐printed [2] design print a compensator uniform thickness clinical target volume (CTV), [3] demonstrate that electron plan is...
Purpose: To examine schemes to grade the severity of metal susceptibility artifacts on image quality using cardiac MRI pulse sequences. Methods: A post‐thoracotomy patient was simulated with a stainless steel sternal wire (Syneture,MA; size=6, diameter=48mm), placed securely an ACR phantom. Phantom scanned 1.5‐T Siemens sequences:1)TrueFISP, 2)Gradient‐Recalled‐Echo (GRE), 3)Turbo‐Spin‐ Echo (TSE), 4)Turbo‐Inversion‐Recovery‐Magnitude (TIRM), 5)Dark‐ blood‐IR‐FS (DBFS) and without...
ConclusionQA results for SRT plans based on gamma index evaluation did not depend the spatial resolution of measurement arrays.This may indicate that standard 2D array phantoms such as Delta4+ designed patientspecific QA IMRT can be successfully used also patient-specific plans.