A5044516572- Advanced Sensor and Energy Harvesting Materials
- Biosensors and Analytical Detection
- ECG Monitoring and Analysis
- Atrial Fibrillation Management and Outcomes
- Biomedical and Engineering Education
- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Microfluidic and Capillary Electrophoresis Applications
- Non-Invasive Vital Sign Monitoring
- Cardiac electrophysiology and arrhythmias
- Thermoregulation and physiological responses
- Cardiac Arrhythmias and Treatments
- Healthcare Technology and Patient Monitoring
- Body Composition Measurement Techniques
- Advanced Chemical Sensor Technologies
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Identification and Susceptibility Testing
- Hemodynamic Monitoring and Therapy
- Artificial Intelligence in Healthcare and Education
- COVID-19 diagnosis using AI
- Cardiovascular and exercise physiology
- Electrical and Bioimpedance Tomography
- Innovative Energy Harvesting Technologies
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
ETH Zurich
2020-2025
University Hospital of Basel
2014-2025
Collegium Helveticum
2023-2025
Institute for Biomedical Engineering
2020-2024
University of Basel
2018
Early detection of atrial fibrillation (AF) is essential for stroke prevention. Emerging technologies such as smartphone cameras using photoplethysmography (PPG) and mobile, internet-enabled electrocardiography (iECG) are effective AF screening. This study compared a PPG-based algorithm against cardiologist's iECG diagnosis to distinguish between sinus rhythm (SR). In this prospective, two-centre, international, clinical validation study, we recruited in-house patients with presumed matched...
The identification and application of biomarkers in the clinical medical fields has an enormous impact on society. increase digital devices rise popularity health-related mobile apps produced a new trove large, diverse, complex data. However, unclear definition biomarkers, population groups, their intersection with traditional hinders discovery validation. We have identified current issues field put forth suggestions to address them during DayOne Workshop participants from academia industry....
AimsAtrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, and its paroxysmal nature makes detection challenging. In this trial, we evaluated a novel App for accuracy to differentiate between patients AF sinus rhythm (SR) using plethysmographic sensor of an iPhone 4S integrated LED only.
Hypertensive disorders are one of the leading causes maternal death worldwide. Several smartphone apps claim to measure blood pressure (BP) using photoplethysmographic signals recorded by cameras. However, no single app has been validated for this use date. We aimed validate a new, promising algorithm. In subgroup analysis iPARR trial (iPhone App Compared With Standard RR Measurement), we tested Preventicus BP algorithm on 32 pregnant women. The was conducted based European Society...
Abstract ST-elevation myocardial infarction (STEMI) triggers a significant inflammatory response. Sweat may offer novel, non-invasive medium for monitoring inflammation. In this prospective study, we characterized the signatures in plasma and sweat collected from skin surface of two patient groups: (1) 18 STEMI patients immediately following percutaneous coronary intervention (exposure) (2) six who underwent outpatient angiography without subsequent (control). Levels 92 biomarkers were...
Abstract Heat stress is a significant public health challenge that leads to an increased risk of serious deterioration, injuries, and loss economic productivity. While the gold standard for monitoring heat continues remain with population-based measurements, straight-forward person-centered approach lacking. Sweat can supply wealth molecular information, ranging from protein levels metabolites; it thus promising biofluid. A thorough investigation sweat’s signature during called for. We...
The possibility to use built-in smartphone-cameras for photoplethysmographic (PPG) recording of pulse waves lead the release numerous health apps, claiming measure blood pressure (BP) based on PPG signals. Even though these apps are highly popular, not a single one is clinically validated. Aim current study was test systolic BP (sBP) estimation by promising new algorithm in large clinical setting.The designed European Society Hypertension International Protocol Revision 2010. Each individual...
Background: Antimicrobial resistance is a major challenge in treating infectious diseases. Therapeutic drug monitoring (TDM) can optimize and personalize antibiotic treatment. Previously, concentrations tissues were extrapolated from skin blister studies, but sweat analyses for TDM have not been conducted. Objective: To investigate the potential of analysis as non-invasive, rapid, bedside method. Methods: We analyzed blood samples 13 in-house patients treated with intravenous cefepime,...
Background:Atrial fibrillation (AF), the most common cardiac arrhythmia, can be detected by smartphones and smartwatches.Introduction:Single-lead ECGs (iECGs) photoplethysmography (PPG) sensors provide opportunity for a broad, simple, easily repeatable rhythm analysis. To reduce unnecessary medical follow-up testing due to false positive results, our aim was find screening approach applicable on smart devices with focus high specificity.Methods:We used PPG measurements from smartwatches iECG...
In this study, we aimed to investigate whether body composition analysis (BCA) derived from bioelectrical impedance vector (BIVA) could be used monitor the hydration status of patients with acute heart failure (AHF) during intensified diuretic therapy.This observational, single-centre study involved a novel, validated eight-electrode segmental analyser perform BCA BIVA an alternating current 100 μA at frequencies 5, 7.5, 50, and 75 kHz. The BCA-derived BIVA-derived parameters were estimated...
<b><i>Background:</i></b> Assuring adequate antibiotic tissue concentrations at the point of infection, especially in skin and soft infections, is pivotal for an effective treatment cure. Despite global issue, a reliable AB monitoring test missing. Inadequate leads to development antimicrobial resistances toxic side effects. β-lactam antibiotics were already detected sweat patients treated with respective intravenously before. With emergence smartphone-based...
The internet of health care things enables a remote connection between professionals and patients wearing smart biosensors. Wearable devices are potentially affordable, sensitive, specific, user-friendly, rapid, robust, lab-independent, deliverable to the end user for point-of-care testing. datasets derived from these known as digital biomarkers. They represent novel patient-centered approach collecting longitudinal, context-derived insights. Adding automated, analytical smartphone...