A5058115332- Transcranial Magnetic Stimulation Studies
- Multiple Sclerosis Research Studies
- Vestibular and auditory disorders
- Pain Management and Treatment
- Neurological disorders and treatments
- Peripheral Neuropathies and Disorders
- Neuroscience and Neural Engineering
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pain Mechanisms and Treatments
- Muscle activation and electromyography studies
- Botulinum Toxin and Related Neurological Disorders
- Migraine and Headache Studies
- EEG and Brain-Computer Interfaces
- Hereditary Neurological Disorders
- Psychosomatic Disorders and Their Treatments
- Olfactory and Sensory Function Studies
- Parkinson's Disease Mechanisms and Treatments
- Functional Brain Connectivity Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Motor Control and Adaptation
- Vagus Nerve Stimulation Research
- Long-Term Effects of COVID-19
- Obsessive-Compulsive Spectrum Disorders
- Peripheral Nerve Disorders
- Musculoskeletal pain and rehabilitation
Université Paris-Est Créteil
2016-2025
Assistance Publique – Hôpitaux de Paris
2016-2025
Hôpitaux Universitaires Henri-Mondor
2016-2025
Lebanese American University
2017-2025
Institut d'Imagerie Biomédicale
2023-2025
Excitabilité Nerveuse et Thérapeutique
2011-2024
Université Paris Cité
2012-2024
Institut de Psychiatrie et Neurosciences de Paris
2023
Laboratoire de Recherche sur la Croissance Cellulaire, la Réparation et la Régénération Tissulaires
2022
Université Paris Sciences et Lettres
2021
Repetitive transcranial magnetic stimulation (rTMS) has been proposed to treat neuropathic pain but the quality of evidence remains low. We aimed assess efficacy and safety neuronavigated rTMS primary motor cortex (M1) or dorsolateral prefrontal (DLPFC) in over 25 weeks. carried out a randomized double-blind, placebo-controlled trial at four outpatient clinics France. Patients aged 18-75 years with peripheral were randomly assigned 1:1 ratio M1 DLPFC-rTMS rerandomized 2:1 active sham-rTMS...
Background In the last few years, transcranial direct current stimulation (tDCS) has emerged as an appealing therapeutic option to improve brain functions. Promising data support role of prefrontal tDCS in augmenting cognitive performance and ameliorating several neuropsychiatric symptoms, namely pain, fatigue, mood disturbances, attentional impairment. Such symptoms are commonly encountered patients with multiple sclerosis (MS). Objective The main objective work was evaluate effects over...
'Conventional' protocols of high-frequency repetitive transcranial magnetic stimulation (rTMS) delivered to M1 can produce analgesia. Theta burst (TBS), a novel rTMS paradigm, is thought greater changes in excitability than 'conventional' protocols. After preliminary experiment showing no analgesic effect continuous or intermittent TBS trains (cTBS iTBS) as single procedures, we used prime subsequent session 10 Hz-rTMS.In 14 patients with chronic refractory neuropathic pain, navigated was...
No study has directly compared the effectiveness of repetitive transcranial magnetic stimulation (rTMS) and direct-current (tDCS) in neuropathic pain (NP). In this 2-centre randomised double-blind sham-controlled study, we efficacy 10-Hz rTMS anodal 2-mA tDCS motor cortex sham contralateral to painful area (3 daily sessions) patients with NP due lumbosacral radiculopathy. Average intensity (primary outcome) was evaluated after each session 5 days later. Secondary outcomes included symptoms...
Importance There is a lack of long-term efficacy and safety data on hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) RNA interference (RNAi) therapeutics in general. This study presents the longest-term to date patisiran for hATTR-PN. Objective To present adults Design, Setting, Participants global open-label extension (OLE) APOLLO randomized clinical trial phase 2 OLE enrolled patients from 43 hospitals or centers across 19 countries between July 2015 August 2017,...
Purpose: Pain and cognitive impairment are frequent symptoms in patients with multiple sclerosis (MS). Neglecting experimental pain paying attention to demanding tasks is reported decrease the intensity. Little known about interaction between chronic neuropathic attentio n disorders MS. Recently, transcranial direct current stimulation (tDCS) was used modulate various motor We aimed study effects of random noise (tRNS), a form electric stimulation, over left dorsolateral prefrontal cortex...
Repetitive transcranial magnetic stimulation (rTMS) can relieve neuropathic pain when applied at high frequency (HF: 5-20 Hz) over the primary motor cortex (M1), contralateral to side. In most studies, rTMS is delivered hand hot spot (hMHS), whatever location. Navigation systems have been developed guide targeting, but their value improve efficacy remains be demonstrated.To compare analgesic of HF-rTMS targeting hMHS (non-navigated procedure) or M1 representation region (navigated...
Polyneuropathy signs (Neuropathy Impairment Score, NIS), neurophysiologic tests (m+7Ionis ), disability, and health scores were assessed in baseline evaluations of 100 patients entered into an oligonucleotide familial amyloidotic polyneuropathy (FAP) trial.We assessed: (1) Proficiency grading neurologic correlation with tests, (2) clinometric performance modified NIS+7 (mNIS+7Ionis ) its subscores disability scores.The mNIS+7Ionis sensitively detected, characterized, broadly scaled diverse...