Nathalie André‐Obadia

ORCID: 0000-0002-0940-7224
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Transcranial Magnetic Stimulation Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traumatic Brain Injury Research
  • Epilepsy research and treatment
  • Cardiac Arrest and Resuscitation
  • Pain Mechanisms and Treatments
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • EEG and Brain-Computer Interfaces
  • Spinal Fractures and Fixation Techniques
  • Pain Management and Treatment
  • Autoimmune Neurological Disorders and Treatments
  • French Historical and Cultural Studies
  • Glycogen Storage Diseases and Myoclonus
  • Psychosomatic Disorders and Their Treatments
  • Cervical and Thoracic Myelopathy
  • Peripheral Neuropathies and Disorders
  • Neurology and Historical Studies
  • Botulinum Toxin and Related Neurological Disorders
  • Spine and Intervertebral Disc Pathology
  • Neurological disorders and treatments
  • Advanced Neuroimaging Techniques and Applications
  • Social Sciences and Governance
  • Meningioma and schwannoma management
  • Neuroscience and Neuropharmacology Research
  • French Urban and Social Studies

Hospices Civils de Lyon
2015-2025

Inserm
2014-2025

Centre National de la Recherche Scientifique
2012-2025

Université Claude Bernard Lyon 1
2014-2025

Centre de Recherche en Neurosciences de Lyon
2014-2025

Hôpital Pierre Wertheimer
2012-2024

Centre Hospitalier Le Vinatier
2013-2024

Hôpital Nord
2015

Hôpital de la Croix-Rousse
2015

Société Française de Parodontologie et d’Implantologie Orale
2014

To assess, against placebo, the pain-relieving effects of high-rate repetitive transcranial magnetic stimulation (rTMS) on neuropathic pain.Double-blind, randomized, cross-over study rTMS placebo in 28 patients. The effect a change coil orientation (posteroanterior vs lateromedial) different subtypes pain was further tested subset 16 Pain relief evaluated daily during 1 week.High-frequency, posteroanterior decreased scores significantly more than placebo. Posteroanterior also outmatched...

10.1212/01.wnl.0000325481.61471.f0 article EN Neurology 2008-09-08

<b>Objective: </b> To clarify the clinical and neurophysiologic spectrum of myoclonus–dystonia patients with mutations <i>SGCE</i> gene. <b>Methods: We prospectively studied 41 consecutive from 22 families documented The had a standardized interview, neurologic examination, detailed including surface polymyography, long-loop C-reflex studies, EEG jerk-locked back averaging. <b>Results: noted homogeneous electrophysiologic pattern myoclonus subcortical origin short jerks (mean 95 msec, range...

10.1212/01.wnl.0000297516.98574.c0 article EN Neurology 2008-03-24

The efficacy of repetitive transcranial magnetic stimulation (rTMS) the motor cortex for neuropathic pain relief is founded on double-blind studies versus placebo. In these studies, however, analgesic effect active interventions remained modest compared with placebo effect. This observation led us to re-evaluate intrinsic action according relative timing and sham rTMS interventions. a randomized controlled study including 45 patients, we that either preceded or followed an rTMS, which could...

10.1016/j.pain.2010.12.027 article EN Pain 2011-02-21

Music listening conveys beneficial effects on cognitive processes in both normal and pathologic cerebral functioning. Surprisingly, no quantitative study has evaluated the potential of music cognition consciousness patients with disorders consciousness.The aim present was to evaluate effect processing consciousness.Using bedside electroencephalographic recording, we acquired 13 event-related potentials patient's first name after either an excerpt preferred (music condition) or a continuous...

10.1177/1545968314565464 article EN Neurorehabilitation and neural repair 2015-02-03

A positive effect of motor cortex stimulation (MCS) (defined as subjective estimations pain relief ≥ 30%) has been reported in 55 - 64% patients. Repetitive magnetic cortical (rTMS) is considered a predictor MCS effect. These figures are, however, mostly based on reports intensity, and have not confirmed the long-term.This study assessed long-term (2 9 years) after epidural its pre-operative prediction by rTMS, using both intensity Quality Life (QoL) scales.Analysis evolution patients...

10.36076/ppj.2014/17/53 article EN Pain Physician 2014-01-14

Abstract Background The therapeutic influence of somatotopic matching between pain topography and motor cortex stimulation site for neuropathic ( NP ) remains controversial. Methods Thirty‐two patients suffering from involving the upper limb n = 20) or face 12) received two high‐frequency rTMS neuronavigated sessions targeting hand cortical areas, versus placebo. target was defined by anatomical MRI EMG responses in all patients, completed 19 them functional . Sessions were separated at...

10.1002/ejp.1156 article EN European Journal of Pain 2017-12-01

Epilepsy impacts cognition during wakefulness. As epileptic activity is present and even augmented sleep, epilepsy could also influence sleep-related cognitive processes. However, whether modulates experiences like dreaming remains poorly known. Here, we prospectively investigated the characteristics determinants of in patients with epilepsy. Consecutive adult no major deficit were recruited an outpatient clinic. They completed a questionnaire about their dreams, sleep over past year....

10.1111/jsr.14464 article EN cc-by-nc-nd Journal of Sleep Research 2025-01-31

Background/Objectives: Cervical spondylotic myelopathy (CDM) is the leading cause of functional disability spinal origin in people over 50 years old. The objective present study was to establish a multiparametric weighted scoring system, easy use daily practice, based on most significant MRI signs and correlated as strongly possible with clinical presentation (mJOA) – SIMS for Severity Imaging Myelopathy Score. Methods: 99 patients who underwent radiological evaluation by mJOA between...

10.20944/preprints202504.1536.v1 preprint EN 2025-04-18

Background/Objectives: Degenerative cervical myelopathy (DCM) is the leading cause of functional disabilities spinal origin in people over 50 years old. The objective present study was to establish a multi-parametric weighted scoring system that easy use daily practice, based on most significant MRI signs and correlated as strongly possible with clinical presentation (mJOA)—we call this SIMS or Severity Imaging Myelopathy Score. Methods: Ninety-nine patients who underwent radiological...

10.3390/brainsci15060557 article EN cc-by Brain Sciences 2025-05-23

Morvan syndrome (MoS) is an autoimmune-mediated that frequently associated with malignant thymoma and autoantibodies targeting contactin protein-like 2 (CASPR2-Abs). Neuropathic pain a frequent clinical feature in MoS—encountered 62% of patients1—but the mechanisms are unknown. We studied 4 patients MoS who had neuropathic investigated whether this could be due to selective involvement small nerve fibers. Written consent was obtained from all patients, study approved by institutional review...

10.1212/wnl.0000000000002037 article EN Neurology 2015-09-24
Coming Soon ...