A5036218510- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Tracheal and airway disorders
- Neuroscience and Neuropharmacology Research
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Organ Transplantation Techniques and Outcomes
- Nausea and vomiting management
- Respiratory Support and Mechanisms
- Non-Invasive Vital Sign Monitoring
- Intraoperative Neuromonitoring and Anesthetic Effects
- Liver Disease and Transplantation
- Acute Myeloid Leukemia Research
- Epilepsy research and treatment
- Blood Coagulation and Thrombosis Mechanisms
- Hematopoietic Stem Cell Transplantation
- Spine and Intervertebral Disc Pathology
- Blood properties and coagulation
- Diamond and Carbon-based Materials Research
- Platelet Disorders and Treatments
- Nitric Oxide and Endothelin Effects
- Neonatal Respiratory Health Research
Fukushima Medical University
2016-2025
Asanogawa General Hospital
2023
Fukushima Medical University Hospital
2019-2020
University of Shizuoka
2020
Kobe University
2020
Aso Iizuka Hospital
2014
Nepean Hospital
2007
Sapienza University of Rome
2007
University of Colorado Denver
2007
Funabashi Municipal Medical Center
2005
Object. The lack of a specified intraoperative method for monitoring anterior choroidal artery (AChA) blood flow insufficiency (BFI) led the authors to devise checking BFI in this during aneurysm surgery. To end, relied on motor evoked potentials (MEPs) elicited by electrical stimulation hand cortex. Methods. study population consisted 108 patients with internal carotid (ICA) aneurysms who underwent surgery via standard frontotemporal craniotomy. After dura mater had been opened, grid...
Abstract Syndecan‐1, ‐2, ‐3, and ‐4 are heparan sulfate proteoglycans that differentially expressed during development wound repair. To determine whether syndecans also involved in brain injury, we examined the expression of syndecan core proteins genes cryo‐injured mouse brain, using situ hybridization. All mRNA transcripts were similarly region surrounding necrotic tissue, exhibiting peak levels at day 7 after injury. Comparison with cellular markers showed reactive astrocytes primary...
We analyzed the effect of a new volatile anesthetic, sevoflurane (2%-5% in oxygen) on electroencephalogram (EEG) neocortex, amygdala, and hippocampus, cortical somatosensory evoked potential (SEP), brainstem reticular multiunit activity (R-MUA) cats. Sevoflurane suppressed background neocortex more than amygdala hippocampus. With increasing concentration sevoflurane, EEG progressed from high-amplitude slow waves to suppression-burst pattern, which was followed by an isoelectric pattern then...
Background Suppression of hypertensive response to noxious stimulation by volatile anesthetics may be a result suppression the stimulation-induced norepinephrine or that cardiovascular catecholamines, both. The is established, but has not been confirmed. authors hypothesized plays major role in suppressing anesthetics. Methods Forty healthy donors for living-related liver transplantation were allocated four groups: receiving 1.2% (end-tidal) isoflurane oxygen and nitrogen, 2.0% isoflurane,...
Nitric oxide (NO) synthase inhibitor (Nω-nitro-L-arginine methyl ester [L-NAME]) has been reported to reduce minimum alveolar anesthetic concentration (MAC) of halothane when administered intravenously (IV) and thermal hyperalgesia, or produce antinociception in the formalin test, intracerebroventricularly (ICV) intrathecally (IT). This study attempts identify site(s) central nervous system (CNS) where L-NAME acts MAC. For this purpose, we examined effects IV, ICV, IT administration on MAC...
To provide a neurochemical basis for the central nervous system actions of nitrous oxide, changes brain dopamine (DA), serotonin (5-HT), norepinephrine (NE), and metabolites DA 5-HT were studied in rats. Thirty male Wistar rats assigned to one five groups according type gas duration exposure. The group, which served as control, exposed air 30 min, four other 75% oxide oxygen 0.5, 1, 2, 4 h, respectively. Animals killed with microwave irradiation, brains divided into seven sections: cerebral...
A congenital deficiency of the coagulation Factor XIII subunit (F A) is a rare autosomal recessive disorder that characterized by life-long bleeding tendency complicated difficulty in healing. Thus far, no molecular genetic analysis this has been reported. In study, we demonstrate abnormalities family with disorder. We performed Northern blot peripheral blood monocytes obtained from propositus and found 4-kb single band F mRNA whose size was identical normal subjects. Exons II-XV, which...
Yamakagashi (Rhabdophis tigrinus) is a species of pit viper present throughout Russia and Eastern Asia. Although R. tigrinus venom known to induce life-threatening hemorrhagic symptoms, the clinical characteristics effective treatment bites remain unknown. The study aimed clarify these issues.Records in Japan Snake Institute between 2000 2013 were retrospectively investigated. following determined: patient characteristics, coagulation fibrinolytic system abnormalities, effect antivenom...
Background : Acetylcholine (ACh) is one of the major excitatory neurotransmitters in central nervous system, and changes neural activity induced by anesthesia alter release ACh. However, effects isoflurane, most widely used volatile anesthetics, on ACh are not known. The present study attempts to clarify dose–effect relationship isoflurane vivo rat brains. Methods Changes extracellular concentration choline cerebral cortex striatum 0.5, 1.0, 1.5 minimum alveolar (MAC) were determined using a...