A5076473268- Visual perception and processing mechanisms
- Neural dynamics and brain function
- Retinal Development and Disorders
- Neuroscience and Neuropharmacology Research
- Neuroscience and Neural Engineering
- Neural and Behavioral Psychology Studies
- Ion channel regulation and function
- Primate Behavior and Ecology
- Memory and Neural Mechanisms
- Vestibular and auditory disorders
- Photoreceptor and optogenetics research
- Neurobiology and Insect Physiology Research
- Glaucoma and retinal disorders
- Tactile and Sensory Interactions
- Zebrafish Biomedical Research Applications
- Nicotinic Acetylcholine Receptors Study
- Cholinesterase and Neurodegenerative Diseases
- Olfactory and Sensory Function Studies
- Face Recognition and Perception
- CCD and CMOS Imaging Sensors
- Animal Vocal Communication and Behavior
- Molecular spectroscopy and chirality
- Pain Mechanisms and Treatments
- Chemical synthesis and alkaloids
- Biochemical effects in animals
University of Rochester
2016-2025
University of Rochester Medical Center
2024
Center for Visual Communication (United States)
2019-2023
National Institutes of Health
2020
Rockefeller University
2020
Salk Institute for Biological Studies
2007-2016
University of California, San Diego
2001-2016
University of St Andrews
1955-2014
Institute of Neurobiology
2011
National Institute of Water and Atmospheric Research
2002
Regulation of circadian period in humans was thought to differ from that other species, with the activity rhythm reported range 13 65 hours (median 25.2 hours) and body temperature average 25 adulthood, shorten age. However, those observations were based on studies exposed light levels sufficient confound estimation. Precise estimation periods endogenous rhythms melatonin, core temperature, cortisol healthy young older individuals living carefully controlled lighting conditions has now...
Abstract— Brain slices were incubated with [ 3 H]GABA in a medium containing aminooxyacetic acid to prevent metabolism of by GABA‐glutamate transaminase. The slices, which rapidly accumulated radioactivity, then continuously perfused and the efflux from tissue was measured. spontaneous consisted an initial rapid phase followed much slower release [H]GABA. After 40 min perfusion 90 per cent radioactivity remained tissue. depolarized electrical stimulation or high potassium concentration (40...
1. The release of gamma-aminobutyric acid (GABA) from the surface posterior lateral gyrus cerebral cortex was measured by a sensitive enzymic fluorimetric assay procedure. Experiments were performed with anaesthetized cats during resting conditions and cortical inhibition produced electrical stimulation brain or geniculate nucleus (l.g.n.).2. average endogenous GABA 0.20 n-mole/ 7 min.cm(2) cortex; this increased both (2.9 times monopolar 7.4 bipolar stimulation) l.g.n. (5.7 release).3....
The common marmoset (Callithrix jacchus), a small-bodied New World primate, offers several advantages to complement vision research in larger primates. Studies the anesthetized have detailed anatomy and physiology of their visual system (Rosa et al., 2009) while studies auditory vocal processing established utility for awake behaving neurophysiological investigations (Lu 2001a,b; Eliades Wang, 2008a,b; Osmanski 2011; Remington 2012). However, critical unknown is whether marmosets can perform...
Conversational turn-taking is an integral part of language development, as it reflects a confluence social factors that mitigate communication. Humans coordinate the timing speech based on behaviour another speaker, learned during infancy. While adults in several primate species engage vocal turn-taking, degree to which similar learning processes underlie its development these non-human or are unique not clear. We recorded natural interactions common marmosets ( Callithrix jacchus )...
Our understanding of how vision functions as primates actively navigate the real-world is remarkably sparse. As most data have been limited to chaired and typically head-restrained animals, synergistic interactions different motor actions/plans inherent active sensing—e.g., eyes, head, posture, movement, etc.—on visual perception are largely unknown. To address this considerable gap in knowledge, we developed an innovative wireless head-mounted eye-tracking system that performs Chair-free...
1. In rabbits anaesthetized with Dial ACh has been collected from the surface of cerebral cortex during stimulation visual pathways.2. The spontaneous release and non-visual areas was found to be similar.3. Stimulation retinae by diffuse light produced a large increase in primary receiving (4.3 times release) smaller (1.9 other parts cortex.4. Direct unilateral electrical lateral geniculate body evoked (3.4 ipsilateral (1.7 contralateral area regions cortex. not mediated transcallosal...
1. Acetylcholine (ACh) has been collected from the visual cortex of anaesthetized rabbits during stimulation lateral geniculate body and after cutting central nervous pathways. ACh also conscious, free‐moving rabbits. 2. After a unilateral ‘vertical’ lesion separating more centrally situated nuclei, release evoked contralateral by was abolished but ipsilateral only reduced. 3. bilateral, ‘horizontal’ thalamic nuclei reticular formation, gave an increased not cortex. 4. The lesions had no...
1 The release of endogenous acetylcholine (ACh) from cerebral cortical slices stimulated at 0.25, 1, 4, 16 and 64 Hz was measured in the presence either physostigmine or atropine.2 Atropine potentiated evoked ACh especially low frequencies resulting an output per stimulus which sharply declined with increasing frequency stimulation, while absence atropine fairly constant.3 [(3)H]-ACh following incubation [(3)H]-choline, as estimated by means rate constants total radioactivity, showed a...
Abstract Fixation constraints in visual tasks are ubiquitous and cognitive neuroscience. Despite its widespread use, fixation requires trained subjects, is limited by the accuracy of fixational eye movements, ignores role movements shaping input. To overcome these limitations, we developed a suite hardware software tools to study vision during natural behavior untrained subjects. We measured receptive fields tuning properties from multiple cortical areas marmoset monkeys who freely viewed...