A5000897090- Business Process Modeling and Analysis
- Service-Oriented Architecture and Web Services
- Semantic Web and Ontologies
- Data Quality and Management
- Prenatal Screening and Diagnostics
- Epigenetics and DNA Methylation
- Privacy-Preserving Technologies in Data
- Flexible and Reconfigurable Manufacturing Systems
- Big Data and Business Intelligence
- Genomic variations and chromosomal abnormalities
- Advanced Database Systems and Queries
- Software System Performance and Reliability
Kiel University
2003-2022
The application of process mining for unstructured data might significantly elevate novel insights into disciplines where is a common format. To efficiently analyze by and to convey confidence the analysis result, requires bridging multiple challenges. purpose this paper discuss these challenges, present initial solutions describe future research directions. We hope that article lays foundations collaboration on topic.
From the study of numerical and structural chromosomal abnormalities, there is convincing evidence accumulating information a direct karyotype to phenotype correlation. Knowledge phenotypic consequences specific imbalance important for genetic counseling prenatal diagnosis. However, unbalanced non-Robertsonian translocations precise correlation difficult predict several reasons: (I) are rare, (II) published case reports often not age-matched, (III) varying breakpoints result in different...