A5003170854- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2020
INTRODUCTION: Data on the associations between esophageal histological lesions and risk of squamous cell carcinoma (ESCC) in general populations are limited. We aimed to investigate these a large Chinese population inform future ESCC screening guidelines. METHODS: performed endoscopic 21,111 participants aged 40–69 years from 3 high-risk areas China 2005–2009, followed cohort through 2016. Cumulative incidence mortality rates were calculated by baseline diagnosis, hazard ratios ESCC, overall...
Introduction Oesophageal cancer (OC) is one of the most common cancers worldwide and about 50% all new cases occurred in China. Population-based screening has been conducted high-risk areas China since 1970s, however, a few factors have limited integration results from previous studies sharing existing resources, such as difference methods protocols, inconsistencies questionnaires for risk investigation, lack standards sample collection incomplete follow-up information. Methods analysis The...
Efficacy of endoscopic screening for esophageal cancer is not sufficiently definitive and lacks randomized controlled trial evidence. The present study proved short‐term efficacy through describing comparing disease stage distributions intervention control populations. Villages from Linzhou Cixian were cluster randomly allocated to the or group target population 52 729 43 068 individuals was 40‐69 years old, respectively, actual enrolled numbers 18 316 21 178, respectively. TNM information...
Premedication in upper gastrointestinal endoscopy for higher lesions detection rate has not been well studied so far. This study aimed to confirm whether premedication could improve the of early cancer or precancerous and mucosal visibility. From July 2015 December 2015, 7200 participants from 6 centers were screened by with one 4 following premedications randomly: (1) water (group D); (2) pronase A); (3) simethicone B); (4) C). Early rates taken as primary endpoints, visibility was...
Background: Helicobacter pylori (H. pylori) is widely accepted to be the most important cause of gastric non-cardia adenocarcinoma (GNCA), while its role in development cardia (CGA) not well defined. We aimed investigate current H. infection relation severity both precancerous and cancerous lesions an Asian population at high risk CGA. Methods: A population-based cross-sectional study was conducted Linzhou County, Henan Province, China. Two thousand three (2,003) randomly selected...
Objectives . Our research is to realize the natural history from dysplasia carcinoma and provide evidence for exploring proper screening intervals. Methods After onset endoscopy screening, 2093 of patients participated in endoscopic follow-up voluntarily. Totally, 101 severe cases, either diagnosed first without treatment or second endoscopy, were included our study. We compared pathologic results their two endoscopies calculate mean median progression time. Results Of 39 cases by only 8...
Objective: To explore the psychological status and related factors in patients with precancerous of esophageal gastric cardia Linzhou Henan. Methods: Clinical psycho-rating scale Social Support Rating Scale (SSRS), Self-Rating Anxiety (SAS, score ≥50 points symptoms anxiety) Depression (SDS, ≥53 depression) were applied to survey life events subjects who aged 40-69 years old participated in"The Early diagnosis Treatment"program cancer hospital from July 2015 Jan 2016. Patients lower...
Objective: To analyze the basic characteristics of patients with hepatocellular carcinoma (HCC), and further explore major factors affecting prognosis HCC patients. Methods: A total 800 were randomly selected from Cancer Hospital, Chinese Academy Medical Sciences. Their clinical follow-up information was obtained medical record. Univariate analysis variance, Kaplan-Meier method Cox regression used to patients' age at diagnosis survival time, etc. Results: The average 55.04 years among all...