A5048067471- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Malaria Research and Control
- SARS-CoV-2 and COVID-19 Research
- Insect Resistance and Genetics
- Long-Term Effects of COVID-19
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- COVID-19 diagnosis using AI
- COVID-19 epidemiological studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- Hernia repair and management
- Drug-Induced Adverse Reactions
- Patient Satisfaction in Healthcare
- Colorectal Cancer Surgical Treatments
- Appendicitis Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Parasites and Host Interactions
- Infectious Diseases and Tuberculosis
- Bacterial Identification and Susceptibility Testing
University of Liverpool
2021-2025
Gold Coast Hospital
2023-2025
Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool
2023-2025
London School of Hygiene & Tropical Medicine
2018-2022
Aintree University Hospitals NHS Foundation Trust
2021
Abstract Insecticide resistance across sub-Saharan Africa may impact the continued effectiveness of malaria vector control. We investigated association between carbamate and pyrethroid with Anopheles gambiae s.l. parity, Plasmodium falciparum infection, molecular insecticide mechanisms in Guinea. Pyrethroid was intense, field populations surviving ten times insecticidal concentration required to kill susceptible individuals. The L1014F kdr -N1575Y haplotype I1527T mutation were significantly...
Abstract Surveillance of malaria vector species and the monitoring insecticide resistance are essential to inform control strategies support reduction infections disease. Genetic barcoding mosquitoes is a useful tool assist high-throughput surveillance resistance, discriminate between sibling detect presence Plasmodium infections. In this study, we combined multiplex PCR, custom designed dual indexing, Illumina next generation sequencing for high throughput single nucleotide polymorphism...
Abstract Background SARS-CoV-2 is frequently shed in the stool of patients hospitalised with COVID-19. The extent faecal shedding among individuals community, and its potential to contribute spread disease, unknown. Methods In this prospective, observational cohort study households Liverpool, UK, participants underwent weekly nasal/throat swabbing detect virus, over a 12-week period from enrolment starting July 2020. Participants that tested positive for were asked provide sample three 14...
Clozapine is an antipsychotic used for treatment-resistant schizophrenia with a significant side effect profile, including agranulocytosis, myocarditis and fever. Clozapine-induced fever often occurs in the first 2 weeks of treatment settle after few days. We report case woman her mid-30s who developed infective symptoms suggestive atypical pneumonia while on clozapine titration. She was 16 days before developing high-grade fever, dry cough, diarrhoea, headache photophobia very high CRP....
Background: SARS-CoV-2 is frequently shed in the stool of patients hospitalised with COVID-19. The rate faecal shedding among individuals community, and its potential to contribute spread disease, unknown. Methods: In this prospective, observational cohort study households Liverpool, UK, participants underwent weekly nasal/throat swabbing detect virus, over a 12-week period from enrolment starting July 2020. Participants that tested positive for were asked provide sample three 14 days later....
Introduction The emergence and rapid spread of COVID-19 have caused widespread catastrophic public health economic impact, requiring governments to restrict societal activity reduce the disease. role household transmission in population SARS-CoV-2, host immunity limiting transmission, is poorly understood. This paper describes a protocol for prospective observational study cohort households Liverpool City Region, UK, which addresses SARS-CoV-2 between members how immunological response...
Abstract The threat of insecticide resistance across sub-Saharan Africa is anticipated to severely impact the continued effectiveness malaria vector control. We investigated effect carbamate and pyrethroid on Anopheles gambiae s.l age, Plasmodium falciparum infection characterized molecular mechanisms in Guinea. Pyrethroid was intense, with survivors ten times insecticidal concentration required kill susceptible individuals. L1014F kdr allele significantly associated mosquito survival...
Abstract The experiences of people hospitalised with COVID-19 are under-researched. We designed a patient satisfaction survey and collected responses (n=94) during Liverpool’s first wave (April-June 2020). Although care was generally rated highly, including among BAME background, sleep-quality communication about medications discharge-planning were identified as areas for improvement. In response, we implemented an education training package healthcare professionals working on wards. During...