- Retinal Development and Disorders
- Photoreceptor and optogenetics research
- Zebrafish Biomedical Research Applications
- Acute Myeloid Leukemia Research
- Hemoglobinopathies and Related Disorders
- Intraocular Surgery and Lenses
- Contact Dermatitis and Allergies
- Renal cell carcinoma treatment
- Allergic Rhinitis and Sensitization
- Optical Imaging and Spectroscopy Techniques
- Retinal Imaging and Analysis
- Migraine and Headache Studies
- Hematopoietic Stem Cell Transplantation
- Primary Care and Health Outcomes
- Medicine and Dermatology Studies History
- Microbial infections and disease research
- MRI in cancer diagnosis
- Prenatal Screening and Diagnostics
- Dermatology and Skin Diseases
- Bacteriophages and microbial interactions
- Advanced Fluorescence Microscopy Techniques
- Glaucoma and retinal disorders
- Renal and related cancers
- Retinal Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
Washington University in St. Louis
2017-2025
Health First
2025
National Institutes of Health
2016-2022
National Institute of Neurological Disorders and Stroke
2016-2022
Purpose: Adequately visualizing the vitreous at times during vitrectomy can be challenging for surgeons. We describe a novel technique using surgical data from machine to differentiate between and balanced salt solution (BSS) in real time. Methods: Vitrectomy was performed ex vivo porcine eyes across range of vacuum levels available vitrectors on Alcon Constellation. These measurements were repeated after BSS. All surgeries recorded masked reviewers extracted flow rates each point. Results:...
Zebrafish retinal cone signals shift in spectral shape through larval, juvenile, and adult development as expression patterns of eight cone-opsin genes change. An algorithm extracting signal amplitudes for the component types is developed tested on two thyroxin receptor β2 (trβ2) gain-of-function lines crx:mYFP-2A-trβ2 gnat2:mYFP-2A-trβ2, allowing correlation between opsin signaling immunoreactivity with different developmental timing cell-type this red-opsin-promoting transgene. Both...
There are four cone morphologies in zebrafish, corresponding to UV (U), blue (B), green (G), and red (R)-sensing types; yet genetically, eight opsins expressed. How physiologically siloed types is not well understood, larvae, physiological spectral peaks unstudied. We use a model infer wavelength peaks, semisaturation irradiances, saturation amplitudes from electroretinogram (ERG) datasets composed of multi-wavelength, multi-irradiance, aspartate-isolated, cone-PIII signals, as compiled many...
ABSTRACT Cluster BE1 Streptomyces bacteriophages belong to the Siphoviridae , with genome sizes over 130 kbp, and they contain direct terminal repeats of approximately 11 kbp. Eight newly isolated closely related cluster phages 43 48 tRNAs, one transfer-messenger RNA (tmRNA), 216 236 predicted open reading frames (ORFs), but few their genes are shared other phages, including those infecting species.
Abstract Zebrafish retinal cone signals shift in spectral shape through larval, juvenile, and adult development as expression patterns of eight cone-opsin genes change. An algorithm extracting signal amplitudes for the component types is developed tested on two thyroxin receptor β2 (trβ2) gain-of-function lines crx:mYFP-2A-trβ2 gnat2:mYFP-2A-trβ2 , allowing correlation between opsin signaling immunoreactivity with different developmental timing cell-type this red-opsin-promoting transgene....
Patient-centered care has been a focus of health for decades but physicians’ consideration patient perspective through trauma informed started recently. Trauma is not just limited to physical and mental spheres also social, cultural, racial, economic realms patient’s life. Despite understanding the multifaceted aspect trauma, physicians, when stressed, continue prioritize their expertise compliance over individual circumstance that led difference in values priorities, focusing on science art...