A5084782521- Silk-based biomaterials and applications
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Polysaccharides and Plant Cell Walls
- Advanced Sensor and Energy Harvesting Materials
- Advancements in Transdermal Drug Delivery
UiT The Arctic University of Norway
2019-2024
A liposomes-in-hydrogel system as an advanced wound dressing for dermal delivery of curcumin was proposed improved chronic therapy. Curcumin, a multitargeting poorly soluble active substance with known beneficial properties healing, incorporated in deformable liposomes to overcome its poor solubility. Chitosan hydrogel served vehicle providing superior healing properties. The novel should assure sustained skin curcumin, and increase retention at the site, utilizing both chitosan improve...
Increasing prevalence of infected and chronic wounds demands improved therapy options. In this work an electrospun nanofiber dressing with liposomes is suggested, focusing on the dressing's ability to support tissue regeneration infection control. Chloramphenicol (CAM) was chosen antibiotic, added nanofibers after first embedded in maintain a sustained drug release. Nanofibers spun from five different polymer blends were tested, where pectin polyethylene oxide (PEO) identified as most...
An active wound dressing should address the main goals in treatment, which are improved healing and reduced infection rates. We developed novel multifunctional nanofibrous dressings with three ingredients: chloramphenicol (CAM), beta-glucan (βG) chitosan (CHI), of βG CHI nanofiber-forming biopolymers isolated from cell walls Saccharomyces cerevisiae shrimp shells, respectively. To evaluate effect each ingredient on nanofibers' morphological features bioactivity, nanofibers both CHI, only βG,...