A5000534858- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Cancer Risks and Factors
- Psychoanalysis and Psychopathology Research
- Chronic Myeloid Leukemia Treatments
- Kruppel-like factors research
- Organ Donation and Transplantation
- Lymphoma Diagnosis and Treatment
- Bone health and treatments
- Organ Transplantation Techniques and Outcomes
- Psychotherapy Techniques and Applications
- Palliative Care and End-of-Life Issues
Ospedale San Carlo
2019-2024
Associazione Italiana Vulvodinia Onlus
2019-2023
Bridgespan Group
2017
The shortage of deceased-donor organs is compounded by donation metrics that fail to account for the total pool possible donors, leading ambiguous donor statistics. We sought assess potential organ procurement organizations (OPOs) utilizing data from Nationwide Inpatient Sample (NIS) 2009-2012 and State Databases (SIDs) 2008-2014. A was defined as a ventilated inpatient death ≤75 years age, without multi-organ system failure, sepsis, or cancer, whose cause consistent with donation. These...
The overwhelming success of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid leukemia (CML) patients has opened a discussion among medical practitioners and the lay public on real possibility pregnancy conception females males with CML. In past 10 years this subject acquired growing interest scientific community specific knowledge been obtained "from bench to bedside". Embryological, pharmacological, pathophysiological studies have merged worldwide patient databases provide roadmap...
Fertility and gonadal function represent one of the most important aspects for long-term lymphoma survivors.The aim our study was to determine possible risk factors, such as age at treatment, chemotherapeutic regimen, protection with oral contraceptives (OCs), gonadotropin-releasing hormone (GnRH) analogues in female patients treated Hodgkin's (HL) or non-Hodgkin (NHL) a reproductive age.Patients between 16 50 years time HL NHL diagnosis were selected. Eligible requested respond...
Introduction Classical Hodgkin Lymphoma (HL) is a lymphoproliferative disease typically diagnosed in the young. The excellent results obtained with current treatment lead to long survival age-related complications affecting patients’ and quality of life. One issue HL patients infertility. This problem can be easily overcome males seminal liquid cryopreservation, however, females it more complex either terms cryopreserved material or age at diagnosis. Moreover, not all chemo- radio-therapies...
In this case report, we describe the outcomes of two heterotopic transplantations cryopreserved ovarian tissue performed in a patient with HL, after 11 and 15 years storage. At age 30, underwent laparoscopy to collect for cryopreservation before chemotherapy radiotherapy. Eleven later she experienced premature failure (POF). As was only interested endocrine function recovery, were abdominal wall above rectus muscle respectively cryopreservation. Before transplantation, samples analyzed...
To describe a population of patients referred for fertility preservation (FP), how to efficiently provide FP care, and care changed over time.This longitudinal observational study enrolled 281 female cancer between 2013 2016 the non-profit organisation Gemme Dormienti ONLUS (GD) care. All underwent same battery instrumental laboratory diagnostic tests. GnRHa therapy was started at least seven days before CTh treatment.From 2016, we observed progressive increase in number Out 251 eligible...
This is a retrospective, multicentric study, aimed to describe the real-life application of fertility preservation methods during treatment in female lymphoma patients, aged 18-40 years old, diagnosed between Oct 1st/2010 and May 31st/2018. Among 414 women included, median age was 28 histologies were: HL 74%, PMBCL 13%, DLBCL 10%, others 3%. First line treatments ABVD 295 (71%), R-CHOP like 102 (25%), higher intensity regimens 17 (4%) cases. Fertility strategies GnRHa 315 (78%), Oral...
A significant increase in breast cancer (BC) rates has been observed among pre-menopausal woman. Considering the higher number of patients (pts) who have not completed their family planning and impact age on fertility, fertility preservation (FP) is proving to be a major challenge. Gemme Dormienti Onlus (GD) an italian association that helps pts by promoting valid model FP counselling. Our aim was identify influence ovarian function (OF) BC pts. We analyzed 100 referred GD. Pts were...