The insertion of an implant in the body a patient raises risk posterior infection and formation biofilm, which can have critical consequences on patient's health be associated with high sanitary cost. While antibacterial agents used to prevent infection, such strategy is time-limited causes bacteria resistance. As alternative biochemical approaches, we propose here use light-induced local hyperthermia plasmonic nanoparticles. This implemented surgical meshes, extensively context hernia...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFullerene-End-Capped Polystyrenes. Monosubstituted Polymeric C60 DerivativesChristine Weis, Christian Friedrich, Rolf Muelhaupt, and Holger FreyCite this: Macromolecules 1995, 28, 1, 403–405Publication Date (Print):January 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://doi.org/10.1021/ma00105a062RIGHTS & PERMISSIONSArticle Views398Altmetric-Citations86LEARN ABOUT THESE METRICSArticle Views are the...

The abnormal joining of anatomic structures after abdominal and pelvic surgery can lead to such major complications as bowel obstruction or infertility. Poly(vinyl alcohol) (PVA) membranes hydrogels were placed over the injured tissue act a physical barrier prevent adhesions from occurring in rabbit sidewall model. sutured into place their slipping curling on moist tissue. Various vitro experiments (including testing for swelling mechanical strength) conducted order better understand...

Herein, a versatile bilayer system, composed by polypropylene (PP) mesh and covalently bonded poly(N-isopropylacrylamide) (PNIPAAm) hydrogel, is reported. The cell adhesion mechanism was successfully modulated controlling the architecture of hydrogel in terms duration PNIPAAm grafting time, crosslinker content, temperature material exposure PBS solutions (below above LCST PNIPAAm). best vitro results with fibroblast (COS-1) epithelial (MCF-7) cells obtained modified porous iPP-g-PNIPAAm...

In this study, a commercial and fully flexible monofilament mesh has been used for the deposition of thermosensitive hydrogel, generated by graft copolymerization <italic>N</italic>-isopropylacrylamide (NIPAAm) <italic>N</italic>,<italic>N</italic>′-methylene bis(acrylamide) (MBA) monomers.

The biopolymer bacterial nanocellulose presents attractive mechanical and anti-adherent properties for innovative hernia repair solutions.

Abstract Herein, a facile approach toward transforming 2D polypropylene flexible mesh material into 4D dynamic system is presented. The versatile platform, composed by substrate of knitted fibers isotactic (iPP) and coating thermosensitive poly( N ‐isopropylacrylamide‐co‐ N,N’ ‐methylene bis(acrylamide) (PNIPAAm‐ co ‐MBA) hydrogel, covalently bonded to the surface, after cold‐plasma surface treatment radical polymerization, intended undergo variations in its geometry via reversible...

The fate of poly(vinyl alcohol) (PVA, 195,000 g/mol) was studied in rabbits and nude mice after intraperitoneal (i.p.) administration. In-vivo fluorescence imaging using allowed for studies tetramethylrhodamine labeled PVA distribution the body tracking urinary excretion. excreted detail collecting urine over a time period 28 days. separated from by dialysis analyzed FTIR spectroscopy, (1)H-NMR size exclusion chromatography (SEC). Even extensive dialysis, it found that showed characteristic...

Smart polypropylene (PP) hernia meshes were proposed to detect surgical infections and regulate cell attachment-modulated properties. For this purpose, lightweight midweight modified by applying a plasma treatment for subsequent grafting of thermosensitive hydrogel, poly(N-isopropylacrylamide) (PNIPAAm). However, both the physical with chemical processes required covalent incorporation PNIPAAm can modify mechanical properties mesh thus have an influence in repair procedures. In work,...

Herein, an innovative self- and pressure-adhesive biomedical implant was developed. Tissue adhesion achieved with a thermosensitive hydrogel based on poly(N-isopropylacrylamide-co-acrylamide), PNIPAAm-co-PAAm, grafted substrate composed of knitted fibers isotactic polypropylene mesh (PP), used as surgical implants. The in vitro studies, carried out porcine skin, showed important role the inclusion acrylamide-based comonomer (AAm) PNIPAAm matrix. bonding, peeling, shearing energies obtained...

The fate of poly(vinyl alcohol) (PVA) weight average molar mass 125,000 g/mol after administration into the peritoneum rabbits has bean studied by various methods. PVA was spin-labeled with a nitroxide radical and then detected in urine using electron spin resonance (ESR) spectroscopy. Furthermore, unlabeled polymer also administered to rabbits, collected, dialyzed, precipitated, excretion confirmed size exclusion chromatography (SEC), FTIR spectroscopy, (1)H NMR ESR SEC results show that,...

Abstract Two different poly(vinyl alcohol)‐based gels (A‐Part Gel) were compared and evaluated as possible adhesion prophylaxis gels. The implanted to act a physical barrier—and thus prevent adhesions—in rabbit sidewall model. absorption time of any barrier is critical parameter, since the wounded tissue needs be covered during healing process. Crosslinking by freeze‐thawing helped prolong To better understand in vivo absorption, investigated various vitro methods such decay measurements...

Abstract Introduction: Formation of postoperative intra‐abdominal adhesions is a severe problem in surgery. Apart from standard surgical procedures, variety different substances available to prevent adhesions, but no universal method has been developed so far. A membrane consisting polyvinyl alcohol (PVA) and carboxymethylcellulose (CMC) demonstrated be antiadhesive. Here, the vitro testing first vivo results rabbit sidewall model are reported. Materials Methods: A‐part® contains PVA/CMC...

Abstract Background Postoperative adhesions occur when fibrous strands of internal scar tissue bind anatomical structures to one another. The most common cause intra-abdominal is previous surgical intervention. Up 74% intestinal obstructions are caused by post adhesions. Although a variety methods and agents have been investigated prevent adhesions, the problem peritoneal remains largely unsolved. Materials serving as an adhesion barrier much needed. Methods/Design This prospective,...

The aim of this study was to find a proper experimental design and evaluate n-butyl-2-cyanoacrylate (Histoacryl) as fixation method for light-weight large pore PP mesh (Synthetic Mesh-1) using the sheep an animal model.Posterior vaginal implantation by means episiotomy used implant 8 ewes which were evaluated macroscopically histologically at 3 months (n = 4) 6 post-surgery. In previous pilot studies anterior evaluated, well different synthetic materials, sizes methods 1 3) during three...

Summary. The aim of this study was to determine, using Western blot, the prevalence anti‐ Candida albicans antibodies in long‐term intensive care patients and characterize specific immune responses that may only occur with invasive candidosis. A total 1751 serum samples from 391 a German multicentre study, which designed determine incidence systemic candidosis, examined. Significantly enhanced antibody production against antigens observed several subgroups patients, i.e. those underlying...

Abstract Aim No standardized test methods currently exist for the characterization of synthetic surgical meshes used in hernia repair and soft tissue reinforcement. While each mesh manufacturer developed their own comparative analysis, these were never harmonized across industry. A subgroup European Association Surgical Suture Industry (EASSI) was constituted, Standardization Meshes Working Group (SSM WG) with objective to reach alignment methods. Materials &amp; Methods The SSM WG agreed on...