A5020693890- Glaucoma and retinal disorders
- Polydiacetylene-based materials and applications
- Immune Cell Function and Interaction
- Epigenetics and DNA Methylation
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Heme Oxygenase-1 and Carbon Monoxide
- Luminescence and Fluorescent Materials
- Advanced Sensor and Energy Harvesting Materials
- Retinal and Macular Surgery
- Cancer-related molecular mechanisms research
- Neonatal Respiratory Health Research
- Neonatal Health and Biochemistry
- Retinal Diseases and Treatments
- Influenza Virus Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- Neural and Behavioral Psychology Studies
- Advanced Materials and Mechanics
- Pediatric Pain Management Techniques
- Genomics and Chromatin Dynamics
- Long-Term Effects of COVID-19
- Photochromic and Fluorescence Chemistry
- Ocular Disorders and Treatments
- Intellectual Property Law
- COVID-19 Clinical Research Studies
Brown University
2023
Rutgers, The State University of New Jersey
2022
University of Connecticut
2019-2020
London Rebuilding Society
2019-2020
Joseph Brant Hospital
2019
University of Pennsylvania
2006-2016
XBiotech (United States)
2016
Penn Presbyterian Medical Center
2016
McGill University
2014
Duke Medical Center
2014
Three-dimensional multiple object tracking (3D-MOT) is a perceptual-cognitive training system based on 3D virtual environment. This the first study to examine effects of 3D-MOT attention, working memory, and visual information processing speed as well using functional brain imaging normative population. Twenty university-aged students were recruited divided into (NT) nonactive control (CON) group. Cognitive functions assessed neuropsychological tests, correlates quantitative...
A 3D integration strategy is applied to fabricate multi-stimuli responsive chromic devices that respond UV, temperature, and mechanical stretching.
A new high-throughput computational strategy was established that improves genomic data mining from MS experiments. The MS/MS were analyzed by the SEQUEST search algorithm and a combination of de novo amino acid sequencing in conjunction with an error-tolerant database tool, operating on 256 processor computer cluster. previously as GenomicPeptideFinder (GPF), enables detection intron-split and/or alternatively spliced peptides when deduced DNA. Isolated thylakoid membranes eukaryotic green...
Ductal Carcinoma in Situ (DCIS) management is challenged by the absence of reliable markers predictive radiotherapy (RT) response, leading to both overtreatment indolent disease and inadequate treatment for aggressive cases. Through whole-exome sequencing 147 DCIS cases, we characterized genomic landscape identified prognosis - specifically risk local recurrence (in situ or invasive) within 10 years after diagnosis. Our analysis revealed that pure frequent mutations genes governing tissue...
Mechanochromic materials have recently received tremendous attention because of their potential applications in humanoid robots, smart windows, strain sensors, anti-counterfeit tags, etc. However, improvements device design are highly desired for practical implementation a broader working environment with high stability. In this article, novel and robust mechanochromism was designed fabricated via facile method. Silica nanoparticles (NPs) that serve as trigger color switch were embedded...
A 3D tubular structure fabricated from the relaxation of pre-stretched 2D precursor is used to develop various stretchable electronics.
Heme oxygenase (HO) degrades cellular heme to carbon monoxide, iron and biliverdin. The HO-1 isoform is both inducible cyto-protective during oxidative stress, inflammation lung injury. However, little known about its precise role function in development. We hypothesized that required for mouse postnatal alveolar development vascular expression of essential protective Neonatal wildtype mutant mice was evaluated by histological molecular methods. Furthermore, these newborn were treated with...
Objective: To investigate the outcomes of strabismus surgery in patients with a prior history scleral buckling procedure for retinal reattachment.
Despite an emerging understanding of the genetic alterations giving rise to various tumors, mechanisms whereby most oncogenes are overexpressed remain unclear. Here we have utilized integrated approach genomewide regulatory element mapping via DNase-seq followed by conventional reporter assays and transcription factor binding site discovery characterize transcriptional regulation medulloblastoma oncogene Orthodenticle Homeobox 2 (OTX2). Through these studies revealed that OTX2 is...
The declined immune response to infection causes significant higher morbidity and mortality in aging spite of the coexisted hyperimmunoglobulinemia (HIG). This study is reveal cellular basis HIG mechanism weakened HA-specific IgG aged mice test cell therapy treatment age-related antibody production deficiency with immunocyte adoptive transfer.BALB/c was immunized Influenza A/Taiwan vaccine challenged same strain virus. ELISA used assess levels total immunoglobulins antigen specific response....
On the basis of pharmacokinetic modelling, high-dose acetaminophen by rectal administration has been recommended for neonates needing antipyretic or analgesic therapy, but safety and efficacy this approach have not established in vivo.The primary objective was to assess neonates, as indicated changes results hepatic renal function tests. The secondary terms Premature Infant Pain Profile-Revised (PIPP-R) score.This single-centre retrospective chart analysis conducted neonatal intensive care...
The expression of Bcl-2 in peripheral blood lymphocytes aged mice was assessed using flow cytometry and compared with young mice. results showed that the frequencies CD3+, CD4+ CD8+ cells expressing were decreased T positively correlated each sub-population but negatively age (old young). In contrast, B (CD19+) Bcl-2+ total as well positive rate CD19+ all increased old mouse age, cell frequency other. These suggest on could play an important role regulation by inhibiting apoptosis during aging.
Postnatal maturation of the lung requires proper alveolar development. In neonatal mice, daily injection Dexamethasone (Dex) resulted in severe disruption septation, whereas with Retinoic Acid (RA) showed more numerous and smaller alveoli. Heme oxygenase-1 (HO1) is expressed at high levels during stage. HO1 also shown to have protective function oxidative stress can increase cell proliferation. We hypothesize that involved postnatal development alteration expression will contribute...