A5031015854- Clostridium difficile and Clostridium perfringens research
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- SARS-CoV-2 detection and testing
- Antimicrobial Resistance in Staphylococcus
- Viral gastroenteritis research and epidemiology
- Dental Research and COVID-19
- Misinformation and Its Impacts
- Influenza Virus Research Studies
- Neutropenia and Cancer Infections
- Microscopic Colitis
- Data-Driven Disease Surveillance
- Infection Control in Healthcare
- COVID-19 and Mental Health
- Nosocomial Infections in ICU
- Hematopoietic Stem Cell Transplantation
- Viral Infections and Outbreaks Research
- Surgical Sutures and Adhesives
- Diverse Scientific Research Studies
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Surgical site infection prevention
- SARS-CoV-2 and COVID-19 Research
- Healthcare cost, quality, practices
- COVID-19 Impact on Reproduction
Memorial Sloan Kettering Cancer Center
2016-2024
University of Gujrat
2020
San Diego State University
2014-2016
Traditional methods for monitoring influenza are haphazard and lack fine-grained details regarding the spatial temporal dynamics of outbreaks. Twitter gives researchers public health officials an opportunity to examine spread in real-time at multiple geographical scales. In this paper, we introduce improved framework outbreaks using social media platform Twitter. Relying upon techniques from geographic information science (GIS) data mining, messages were collected, filtered, analyzed thirty...
Existing influenza surveillance in the United States is focused on collection of data from sentinel physicians and hospitals; however, compilation distribution reports are usually delayed by up to 2 weeks. With popularity social media growing, Internet a source for syndromic due availability large amounts data. In this study, tweets, or posts 140 characters less, website Twitter were collected analyzed their potential as seasonal influenza.There three aims: (1) improve correlation tweets...
Surgical-site infection (SSI) is associated with significant healthcare costs. To reduce the high rate of SSI among patients undergoing colorectal surgery at a cancer centre, comprehensive care bundle was implemented and its efficacy tested.A pragmatic study involving three phases (baseline, implementation sustainability) conducted on treated consecutively between 2013 2016. The intervention included 13 components related to: bowel preparation; oral intravenous antibiotic selection...
New York City (NYC) experienced a surge of coronavirus disease 2019 (COVID-19) cases in March and April 2020. Since then, universal polymerase chain reaction (PCR)-based surveillance testing personal protective equipment (PPE) measures are wide use procedural settings. There is limited published experience on the utility sustainability PCR-based areas with receding consistently low community COVID-19 rates.The study was conducted at tertiary care cancer center NYC from 22 to August...
Abstract Background There is limited information on the risk of hospital-acquired coronavirus disease 2019 (COVID-19) among high-risk hospitalized patients after exposure to an infected patient or healthcare worker (HCW) in a nonoutbreak setting. Methods This study was conducted at tertiary care cancer center New York City from 10 March 2020 until 28 February 2021. In early April 2020, institution implemented universal severe acute respiratory syndrome 2 (SARS-CoV-2) testing admission and...
Abstract We used a self-reporting system to compare symptom frequency of hospital personnel with coronavirus disease 2019 before and after the emergence Omicron variant. was more likely result in asymptomatic carriage (7% vs 12%; P = .009), fewer symptoms were observed those booster vaccination.
In 2015, Clostridium difficile testing rates among 30 US community, multispecialty, and cancer hospitals were 14.0, 16.3, 33.9/1,000 patient-days, respectively. Pooled hospital onset 0.56, 0.84, 1.57/1,000 Higher may artificially inflate reported of C. infection. surveillance should consider frequency.
An evidence-based triage plan for cellular therapy distribution is critical in the face of emerging constraints on healthcare resources. We evaluated impact treatment delays related to COVID-19 patients scheduled undergo hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell (CAR-T) at our center. Data were collected real time between March 19 and May 11, 2020, who delayed therapy. proportion ultimately received therapy, reasons not proceeding changes disease health...
In this retrospective study of 105 severe acute respiratory coronavirus virus 2 (SARS-CoV-2)–infected cancer patients with longitudinal nasopharyngeal sampling, the duration viral shedding and time to attain cycle threshold >30 was longer in hematologic malignancy than those solid tumors. These findings have important public health implications.
Multilocus sequence typing (MLST) is a low-resolution but rapid genotyping method for Clostridioides difficile . Whole-genome sequencing (WGS) has emerged as the new gold standard C. typing, cost and lack of standardization still limit broad utilization. In this study, we evaluated potential to combine portability MLST with increased resolution WGS cost-saving approach routine typing.
Abstract Background: Universal masking within healthcare settings was adopted to combat the spread of coronavirus disease 2019 (COVID-19). In addition mitigating risk for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, it also had an added benefit preventing nosocomial transmission other respiratory viral diseases. Objective: This study examines impact intervention on infections (RVI) in vulnerable sub-populations people with cancer at a tertiary care hospital....
Abstract Background: SARS-CoV-2 asymptomatic surveillance testing (AST) is a common strategy to minimize the risk of nosocomial infection in patients and healthcare personnel. In contrast admission screening, post-admission AST was less widely adopted. Objective: This study describes diagnostic yield serial SARS-COV-2 hospitalized at large cancer center with mostly double-occupancy rooms. Design: Retrospective cohort design. Post-admission tests were examined over 18 month period. Positive...
Abstract Background Legionella pneumophila (L. pneumophila) infections can severely affect immunocompromised patients. Found in water systems, the presence of healthcare sources creates an opportunity for hospital acquired infections. After a high-risk patient L. June 2022 while at Memorial Sloan Kettering (MSK), tertiary cancer center, Infection Control worked to identify source. A timeline events is illustrated Figure 1. Between inpatient admissions, stayed MSK’s outpatient residence known...
Abstract Background The incubation period of C. difficile infection (CDI) is highly variable. Infections may be diagnosed weeks after initial acquisition bacterial spores. Such cases CDI have onset in the community a recent hospitalization, or upon readmission, and are characterized as community-onset healthcare-facility associated (CO-HCFA) by current surveillance methods. Aim: With application multi-locus sequence typing (MLST), our study seeks to characterize genetic concordance between...
Abstract Background Polymerase chain reaction (PCR) based diagnostic testing for the detection of toxigenic Clostridium difficile infection (CDI) does not distinguish between carriers and patients with true CDI. As a result, CDI is over-diagnosed in hospitalized diarrhea. Unnecessary generates false positives several downstream sequelae. Aim: The aim this study was to reduce unnecessary through an electronic alert, targeted education, implementation evidence-based laboratory policy. Methods...
Abstract Background Transmission of healthcare-associated Clostridium difficile infection (HA-CDI) has been shown to occur directly or indirectly through a contaminated environment. At tertiary-care cancer center, HA-CDI rates were higher for pediatric units than other general oncology units. To address the problem, multidisciplinary team, including Infection Control, Nursing, and Environmental Services (EVS), was convened identified refusals room clutter as barriers proper cleaning rooms on...
The aim of this study was to evaluate the change in strain-type distribution after eliminating testing formed and laxative induced diarrheal stool. Beginning July 2013, all Clostridium difficile-positive stool samples by Cepheid’s GeneXpert were routinely typed using Multi-Locus Sequence Typing (MLST). MLST performed as previously described (1). After implementation rejection policy re-education staff, strain type (ST) among tested analyzed compared with historic data. evaluation our...
Abstract Background Device-related infections account for a fourth of all HAIs. Hepatic artery infusion pump (HAIP) devices are used to deliver chemotherapy directly into the hepatic artery. This device is primarily in patients with colorectal cancer management unresectable metastases. We describe infection rates and outbreak MRSA-related newly placed HAIPs. Methods In December 2018, cluster 3 MRSA cases was identified within 15–26 days HAIP insertion. From January 1, 2017 31, culture proven...
Abstract Background The Society for Healthcare Epidemiology of America (SHEA) recommends that surveillance healthcare facility-onset C. difficile infections (HO CDI) be conducted to detect elevated rates or outbreaks CDI and stratify data by hospital unit when possible facilitate detection clusters. At Memorical Sloan Kettering Cancer Center, strain typing isolates using multi-locus sequence (MLST) is performed routinely in real time inform control efforts. Genotyping can conclusively...