A5033782526- Sperm and Testicular Function
- Reproductive Physiology in Livestock
- Reproductive System and Pregnancy
- Animal Nutrition and Physiology
- Liver Disease Diagnosis and Treatment
- Genetic and phenotypic traits in livestock
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Peroxisome Proliferator-Activated Receptors
- Reproductive Biology and Fertility
- Meat and Animal Product Quality
- Aquaculture Nutrition and Growth
- Lipid metabolism and biosynthesis
- MicroRNA in disease regulation
- Adipose Tissue and Metabolism
- Cholesterol and Lipid Metabolism
- Cancer, Lipids, and Metabolism
- Antioxidant Activity and Oxidative Stress
- Bone Metabolism and Diseases
- Hormonal and reproductive studies
- Metabolism, Diabetes, and Cancer
- Urologic and reproductive health conditions
- Aquaculture disease management and microbiota
- Metabolomics and Mass Spectrometry Studies
- Fungal and yeast genetics research
- Genetic Neurodegenerative Diseases
Sichuan Agricultural University
2020-2024
Southwest University
2024
Ministry of Agriculture and Rural Affairs
2023-2024
Abstract Background All birds reproduce via internal fertilization, but only ~3% of male possess the external genitalia that allows for intromission. Waterfowl (e.g., duck and goose) are representatives them, development geese is directly related to mating ability. Notably, some show abnormal during ontogenesis. However, until now little known about molecular mechanisms in goose. In present study, comparative transcriptomic analyses were performed on hypothalamus, pituitary gland, testis,...
Due to the demand for modern goose production and pressure of environmental protection, rearing systems geese are changing from traditional waterside intensive such as floor (FR) cage (CR) systems. However, little is known about effects different on intestinal functions cecal microbial composition. Therefore, this study aimed compare histomorphology composition differences in reared under CR FR at 270 d age. Histomorphological analysis showed that ileal villus height (VH) crypt depth (CD)...
Presently, excessive fat deposition is the main reason to limit development of duck industry. In production, methods restricted feeding (RF) were widely used reduce lipid ducks. The liver (L), abdominal adipose (AA), and subcutaneous (SA) tissues metabolism However, mechanisms ducks under RF have not been fully clarified. this study, in order better understand RF, a total 120 male Nonghua randomly divided into free group (FF, n = 60) (RF, 60), then comparative transcriptomic analysis L, AA,...
As the largest peripheral lymphoid organ in poultry, spleen plays an essential role regulating body’s immune capacity. However, compared with chickens and ducks, information about age- breed-related changes goose remains scarce. In this study, we systematically analyzed age-dependent morphological, histological, transcriptomic characteristics between Landes (LG; Anser anser ) Sichuan White (SWG; cygnoides ). The results showed a gradual increase splenic weights for both LG SWG until week 10,...
Poultry broodiness can cause ovarian atresia, which has a detrimental impact on egg production. Non-coding RNAs (ncRNAs) have become one of the most talked-about topics in life sciences because increasing evidence their novel biological roles regulatory systems. However, molecular mechanisms ncRNAs functions and processes chicken development remain largely unknown. Whole-transcriptome RNA sequencing ovaries laying chickens was thus performed to identify ncRNA associated with atresia...
Semen quality is the most important indicator in evaluating drake fecundity. At present, low semen has become a major factor restricting development of artificial insemination (AI) technology ducks. Numerous studies have indicated that seminal plasma proteins play crucial role quality, but mechanism regulating drakes remains unclear. Thus, objective this study was to identify associated with by comparing proteomic profile high-quality (HQS) and low-quality (LQS). Using label-free MS-based...
Geese, descendants of migratory birds, have preserved the distinct reproductive and lipid metabolism traits their wild ancestors. Therefore, compared to other poultry, geese lower egg production ability a more sensitive susceptibility fatty liver. Recent research underscores impact disorders on female health. In this context, we observed (RD) anomalies in certain populations. This study systematically elucidated differences between RD normal at various levels, including genomics,...
Different rearing systems have varying effect on animal welfare and meat quality of poultry. Currently, there are no established standards for the Chinese indigenous chickens. Our study aimed to investigate effects different quality, gene profiles, metabolites chickens (Nanchuan chicken). 10-wk-old Nanchuan (n=360) were randomly divided into 3 groups (cage, net, free-range groups), with 6 replicates per group (20 replicate). The experiment lasted 12 wk. At 154-days-old, 36 healthy (6 males...
Pectoral muscle development is an important economic trait. According to the different essence, can be divided into 2 processes: embryonic fiber generation and postnatal hypertrophy, hypertrophy has a greater impact on than number of fibers formed during phase in poultry. However, underlying mechanisms regulating goose pectoral muscles have not been elucidated. Therefore, purpose present study was conduct transcriptome sequencing both Landes (LD) Sichuan White (SW) geese at 6, 10, 30 weeks...
Objective: Unlike mammals, goose fatty liver shows a strong tolerance to acids without obvious injury. Stearyl-coenzyme A desaturase 1 (SCD1) serves crucial role in desaturation of saturated (SAFs), but its the SAFs hepatocytes has not been reported. This study was conducted explore <i>SCD1</i> regulating palmitic acid (PA) primary hepatocytes. Methods: 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide examined reflect effect PA on viability, and quantitative...
Currently, FRS and CRS are the two predominant dryland rearing systems in goose industry. However, effects of these on growth performance health, as well underlying mechanisms, have not been fully clarified. Thus, this study aimed to compare immune status, investigate genome-wide transcriptomic profiles spleen geese, between at 270 d age. Phenotypically, body weight size traits were higher geese under FRS, while organ index (p < 0.05). Noticeably, bursa Fabricius was degenerated, that...
The lower egg production of geese (20~60 eggs per year) compared with chicken and duck limits the development industry, while yolk weight fatty liver susceptibility was higher than that other poultry. Therefore, relationship between lipid metabolism laying performance remains to be explored. Phenotypically, we observed fat content high-, low-, no-egg groups decreased in turn, abdominal increased turn. For transcriptional regulation, KEGG pathways related were enriched all pairwise...
Egg weight is an important indicator of egg phenotypic traits, which directly affects the economic benefits poultry industry. In present research, laying ducks were classified into high (HEW) and light (LEW) groups. To reveal underlying mechanism that may be responsible for difference, integrated analysis transcriptomes serum metabolomics was performed between two The results showed extremely significant differences (P < 0.01) in total at 300 d, average HEW LEW 733, 591, 82, 74...
Semen volume is an important factor in artificial insemination (AI) of ducks. In drakes, seminal plasma that produced by the epididymis determines semen volume. However, mechanism regulating drakes remains unclear. Therefore, aim present study was to preliminarily reveal through comparing epididymal histomorphology and mRNA expression profiles between with high-volume (HVS) low-volume (LVS). Phenotypically, HVS group more sperm than LVS group. addition, compared group, ductal square ductuli...
Evidence has shown that oestrogen suppresses lipids deposition in the liver of mammals. However, molecular mechanism action hepatic steatosis geese yet to be determined. This study aimed investigate effect on lipid homeostasis at different states hepatocytes vitro. The results showed an vitro model was induced by 1.5 mM sodium oleate via detecting viability and content lipids. When normal were administrated with concentrations (E2 ), expression levels diacylglycerol acyltransferase 2...
This study was conducted to clone and compare the molecular characteristics of deiodinase 2 (DIO2) gene between Sichuan White geese Landes geese, analyze association polymorphisms DIO2 head dimensions in Tianfu meat geese.The coding sequence cloned by polymerase chain reaction vector ligation aligned DNAMAN software. A total 350 were used genotype measure dimensions. Association analysis carried out.An 840-bp obtained comparison identified four polymorphic loci geese. Further showed that...
Over-accumulation of triglycerides (TGs) in goose hepatocytes leads to the formation fatty acid liver. Phosphoenolpyruvate carboxylase kinase 1 (PEPCK) is regarded as rate-limiting enzyme for gluconeogenesis, and there evidence that PEPCK involved regulating hepatic glucolipid metabolism. Hence, we proposed may have a role steatosis. To test our hypothesis, present study was conducted firstly determine sequence characteristics then explore its overfeeding-induced Our results showed encodes...
Abstract Background Unlike mammals, goose fatty liver shows a strong tolerance to acids without obvious injury. Stearyl-coenzyme A desaturase 1 (SCD1) serves crucial role in desaturation of saturated (SAFs), but its the SAFs hepatocytes has not been reported. This study was conducted explore SCD1 regulating palmitic acid primary hepatocytes. Methods To evaluate cultured hepatocytes, MTT examined reflect effect on cell viability, and quantitative PCR used detect mRNA expression levels several...