Raina E. Sacksteder

ORCID: 0000-0003-0259-3631
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About
Contact & Profiles
Research Areas
  • Circadian rhythm and melatonin
  • Biomedical and Engineering Education
  • Spaceflight effects on biology
  • Dietary Effects on Health
  • Experimental Learning in Engineering
  • Genetics, Bioinformatics, and Biomedical Research
  • Neuroendocrine regulation and behavior
  • Genetics, Aging, and Longevity in Model Organisms

University of California, Santa Cruz
2022-2024

Project-based learning (PBL) has long been recognized as an effective way to teach complex biology concepts. However, not all institutions have the resources facilitate project-based coursework for students. We developed a framework facilitating PBL using remote-controlled internet-connected microscopes. Through this approach, one lab facility can host experiment many students around world simultaneously. Experiments on platform be run timescales and with materials that are typically...

10.1016/j.heliyon.2022.e11596 article EN cc-by Heliyon 2022-11-01

Abstract The circadian clock is a highly coordinated, cell-autonomous process that regulates the daily internal rhythms of biological organisms. Circadian clocks have been identified in various organisms, including mammals, invertebrates, cyanobacteria, and plants. zebrafish ( Danio rerio ) practical model for studying vertebrate due to its small size, ease manipulation, gene tractability, direct light responsiveness. Several studies revealed bacterial, viral, parasitic infections can impact...

10.1101/2024.02.20.581283 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-22

Abstract Project-based learning (PBL) has long been recognized as an effective way to teach complex biology concepts. However, not all institutions have the resources facilitate project-based coursework for students. We developed a framework facilitating PBL using remote-controlled internet-connected microscopes. Through this approach, one lab facility can host experiment allowing simultaneous interaction by many students worldwide. Experiments on platform be run timescales and with...

10.1101/2022.08.05.502091 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2022-08-11

Abstract The circadian clock is a cell-autonomous process that regulates daily internal rhythms by interacting with environmental signals. Reports across species show infection can alter the expression of genes; however, in teleosts, these effects are influenced light exposure. Currently, no reports analyze direct bacterial exposure on zebrafish clock. Using Z3 cells, we demonstrate to heat-killed Streptococcus pneumoniae (HK-Spn) augments core repressive factors light- and time-dependent...

10.1038/s41598-024-78888-0 article EN cc-by Scientific Reports 2024-11-13
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