A5101504806- Amoebic Infections and Treatments
- HIV/AIDS oral health manifestations
- Pediatric Hepatobiliary Diseases and Treatments
- NF-κB Signaling Pathways
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Pancreatitis Pathology and Treatment
- Oral microbiology and periodontitis research
- Ocular Infections and Treatments
Jilin University
2023
Humboldt-Universität zu Berlin
2020-2021
Charité - Universitätsmedizin Berlin
2020-2021
Freie Universität Berlin
2020-2021
A metagenomics analysis showed a strongly increased frequency of the protozoan Entamoeba gingivalis in inflamed periodontal pockets, where it contributed second-most abundant rRNA after human rRNA. This observation and close biological relationship to histolytica, which causes inflammation tissue destruction colon predisposed individuals, raised our concern about its putative role pathogenesis periodontitis. Histochemical staining gingival epithelium from generalized severe chronic...
The protozoan Entamoeba gingivalis colonizes the healthy oral mucosa with a prevalence of 15%. Colonization can be asymptomatic, and it is considered not pathogenic. However, able to invade lacerated mucosa, where ingests fragments live cells, suggesting pathogenous potential. Here, we characterized transcriptomes gingival cells after infection E. using RNA sequencing observed pathogen interaction epithelial monolayer barrier by scanning electron microscopy. In fibroblast strongest...
ABSTRACT Aspergillus fumigatus is an opportunistic pathogen that infects immunocompromised patients and imposes a heavy burden on global health. Searching for key genes in host resistance to A. infection can help us understand the mechanisms of -host interactions provide new targets treatment fungal infections. TRAF3 one intracellular adapter proteins innate immune response regulates signaling various cellular processes, including defense against pathogens. However, mechanism remains...