Yalu Yan

ORCID: 0000-0003-0270-3124
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About
Contact & Profiles
Research Areas
  • Infant Nutrition and Health
  • Breastfeeding Practices and Influences
  • Digestive system and related health
  • Probiotics and Fermented Foods
  • Child Nutrition and Water Access
  • Microbial Metabolites in Food Biotechnology
  • Fatty Acid Research and Health
  • Enterobacteriaceae and Cronobacter Research
  • Child Nutrition and Feeding Issues
  • Clinical Nutrition and Gastroenterology
  • Animal Nutrition and Physiology
  • Food composition and properties
  • Coconut Research and Applications
  • Bone and Dental Protein Studies
  • Protein Interaction Studies and Fluorescence Analysis
  • Machine Learning and Algorithms
  • Antimicrobial Peptides and Activities
  • Pediatric health and respiratory diseases
  • Cholinesterase and Neurodegenerative Diseases
  • Diabetes and associated disorders
  • Escherichia coli research studies
  • Consumer Perception and Purchasing Behavior
  • Face recognition and analysis
  • Bayesian Methods and Mixture Models
  • Biochemical effects in animals

Inner Mongolia Yili Industrial Group (China)
2022-2025

Inner Mongolia Electric Power Survey & Design Institute (China)
2024-2025

Dairy Management
2025

Institute of Process Engineering
2020

University of Alberta
2013-2019

Background Prematurity or low birth weight (LBW), poses a significant challenge in global health. Exploring appropriate and effective nutritional interventions is crucial for the growth development of LBW infants. Hydrolyzed protein formula has been suggested as potential solution to prevent intestinal dysfunction improve digestion absorption Objectives This study aimed investigate benefits hydrolyzed on feeding intolerance, morphological development, microbiota piglet model. Methods A total...

10.3389/fnut.2024.1439110 article EN cc-by Frontiers in Nutrition 2024-10-28

Lacto-N-neotetraose (LNnT) is a prevalent neutral core human milk oligosaccharides (HMOs) recognized for its numerous benefits to infant health. In formula, galactooligosaccharide (GOS) are frequently used as substitutes HMOs. However, the regulatory roles of LNnT and GOS in early intestinal development not yet fully understood. This study aims elucidate effects on during life. Our findings show that administering or significantly increased spleen liver indices mice at postnatal day 21....

10.1021/acs.jafc.4c10055 article EN Journal of Agricultural and Food Chemistry 2025-03-06

It is proven that β-amyloid (Aβ) aggregates containing cross-β-sheet structures led to oxidative stress, neuroinflammation, and neuronal loss via multiple pathways. Therefore, reduction of Aβ neurotoxicity inhibiting aggregation or dissociating toxic into nontoxic forms might be effective therapeutic methods for Alzheimer’s disease (AD) treatment. This study was designed explore interference chitosan oligosaccharides (COS) on β-(1-42)-amyloid protein (Aβ42) Aβ42-induced cytotoxicity. Here it...

10.3390/md18100488 article EN cc-by Marine Drugs 2020-09-25

The short-chain fatty acids (SCFAs) contained in breast milk play a key role infant growth, affecting metabolism and enhancing intestinal immunity by regulating inflammation.

10.3389/fmicb.2024.1356462 article EN cc-by Frontiers in Microbiology 2024-02-19

Proteins in breast milk play an important role the growth and development of infants. This study aims to explore correlation between functional proteins infant gut microbiota. Twenty-three mothers their infants were enrolled samples fecal collected. Breast protein content was determined by UPLC-MS/MS, 16S rRNA sequencing employed analyze microbiota infant. The results indicated that secretory immunoglobulin A (sIgA) positively correlated with abundance Veillonella parvula. κ-casein...

10.3389/fmicb.2023.1239501 article EN cc-by Frontiers in Microbiology 2023-09-13

Breast milk (BM) is the optimal nutrition source for infants, providing highly digestible proteins. In contrast, digestibility of proteins in infant formula (IF) varies, influenced by differences such as α-lactalbumin (α-La) and β-casein (β-CN). This study aimed to evaluate true ileal (TID) amino acids (AAs) BM IF with varying α-La β-CN contents using neonatal piglets. Twenty-four 11-day-old piglets (4 groups; 6 replicates/group) received either a nitrogen-free diet, (high (HIF) 1.74 g/100...

10.1021/acs.jafc.4c10520 article EN Journal of Agricultural and Food Chemistry 2025-03-03

Previous studies have demonstrated the beneficial effects of 2'-fucosyllactose (2'-FL) and osteopontin (OPN) in modulating intestinal mucosal immunity. Nevertheless, potential synergistic interactions underlying mechanisms 2'-FL OPN not been fully elucidated. To address this question, study employed Sprague-Dawley (SD) rats to establish a lipopolysaccharide (LPS)-induced model simulating human microbiota-associated barrier damage. The findings indicate that combined administration exerts...

10.1039/d4fo05287k article EN Food & Function 2025-01-01

Enterotoxigenic Escherichia coli (ETEC) K88 causes diarrhea in weaned piglets and represent a suitable model system for ETEC causing childhood diarrhea. This study aimed to evaluate the effects of oligosaccharides against adhesion porcine erythrocytes with two bioassays. Galactosylated chitosan-oligosaccharides (Gal-COS) were synthesized through transgalactosylation by β-galactosidase. Fractions 2-5 Gal-COS obtained cation exchange size exclusion chromatography. acetylated chemical...

10.1021/acs.jafc.7b01741 article EN Journal of Agricultural and Food Chemistry 2017-06-08

2′-Fucosyllactose (2'-FL) shows the potential to support intestinal health as a natural prebiotic that bridges gap between infant formula feeding and breastfeeding. However, effect mechanism of 2'-FL in improving permeability are not clear. In this study, we constructed human microbiota-associated (HMA) mouse models by colonizing healthy feces mice with antibiotic-depleted microbiota. The protective on was explored using HMA models, combination metagenomics used analyze possible mechanisms...

10.26599/fshw.2024.9250021 article EN cc-by-nc-nd Deleted Journal 2024-02-01

Poisson sampling is a method for unequal probabilities with random sample size. There exist several implementations of the design, fixed size, which almost all are rejective methods, that is, not always accepted. Thus, existing methods can be time-consuming or even infeasible in some situations. In this paper, fast and non-rejective method, efficient large populations, proposed studied. The new design selecting size inclusion probabilities. For population very close to strict πps similar...

10.1080/02664763.2012.756861 article EN Journal of Applied Statistics 2013-01-02

Introduction Brain development during infancy is crucial for later health and development. Although Milk Fat Globule Membrane (MFGM) has been demonstrated to enhance brain development, further investigation needed determine the optimal dose. Methods In this study, 80 piglets aged 2 days were randomly assigned four groups: Control group, MFGM-L (1.74 g MFGM per 100 diet), MFGM-M (4.64 MFGM-H (6.09 diet). Daily body weight milk intake of recorded until 31 postnatal. Learning memory abilities...

10.3389/fnut.2023.1248809 article EN cc-by Frontiers in Nutrition 2023-11-23

This study compared the lipid content, total and sn-2 fatty acids, acid distribution, levels of 1, 3-dioleoy-2-palmitoyl glycerol (OPO), 1-oleoyl-2-palmitoyl-3-linoleoyl (OPL), 3-linoleoyl-2-palmitoyl (LPL) in colostrum mature milk (n = 122) from seven ethnic minorities China. Compared with Han breast milk, content saturated (SFA) trans (TFA) (especially Uygur) was higher, while monounsaturated (MUFA) polyunsaturated (PUFA) were lower. may be related to high intake meat products. In terms...

10.2139/ssrn.4704674 preprint EN 2024-01-01
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