A5114029681- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Animal Nutrition and Physiology
- Neuroblastoma Research and Treatments
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Meningioma and schwannoma management
- Gut microbiota and health
- RNA modifications and cancer
- Genomics and Phylogenetic Studies
- Child Nutrition and Water Access
- MRI in cancer diagnosis
- Infant Nutrition and Health
- Neurogenesis and neuroplasticity mechanisms
- Epigenetics and DNA Methylation
- Hedgehog Signaling Pathway Studies
- Stochastic Gradient Optimization Techniques
- Evolutionary Algorithms and Applications
- Air Quality and Health Impacts
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Brain Tumor Detection and Classification
- Machine Learning and Data Classification
- Ginseng Biological Effects and Applications
- Advanced Image Processing Techniques
Institute of Subtropical Agriculture
2020-2025
Chinese Academy of Sciences
2020-2025
Hunan Normal University
2023-2025
Agroécologie
2025
University College London
2024
Southern Medical University
2023
Yuhuangding Hospital
2022-2023
Capital Medical University
2017-2023
Beijing Tian Tan Hospital
2017-2023
Changsha Normal University
2023
MicroRNAs (miRNAs) are key regulators of gene expression involved in a broad range biological processes. MiRNASNP aims to provide single nucleotide polymorphisms (SNPs) miRNAs and genes that may impact miRNA biogenesis and/or target binding. Advanced research provided abundant data about expression, validated targets related phenotypic variants. In miRNASNP v2.0, we have updated our previous database with several new features, including: (i) level correlation different tissues, (ii) linking...
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy. The understanding of its gene expression regulation and molecular mechanisms still remains elusive. Started from experimentally verified T-ALL-related miRNAs genes, we obtained 120 feed-forward loops (FFLs) among TFs through combining target prediction. Afterwards, a T-ALL miRNA TF co-regulatory network was constructed, significance tested by statistical methods. Four in the miR-17-92 cluster four...
Brainstem gliomas are a heterogeneous group of tumors that encompass both benign cured with surgical resection and highly lethal cancers no efficacious therapies. We perform comprehensive study incorporating epigenetic genomic analyses on large cohort brainstem gliomas, including Diffuse Intrinsic Pontine Gliomas. Here we report, from DNA methylation data, distinct clusters termed H3-Pons, H3-Medulla, IDH, PA-like, each associated unique clinical profiles. The majority within H3-Pons...
This paper reviews the NTIRE 2023 challenge on efficient single-image super-resolution with a focus proposed solutions and results. The aim of this is to devise network that reduces one or several aspects such as runtime, parameters, FLOPs, activations, memory footprint, depth RFDN while at least maintaining PSNR 29.00dB DIV2K validation datasets. had 272 registered participants, 35 teams made valid submissions. They gauge state-of-the-art for super-resolution.
MicroRNAs (miRNAs) play key regulatory roles in various biological processes and diseases. A comprehensive analysis of large scale small RNA sequencing data (smRNA-seq) will be very helpful to explore tissue or disease specific miRNA markers uncover variants. Here, we systematically analyzed 410 human smRNA-seq datasets, which samples are from 24 tissue/disease/cell lines. We tested the mapping strategies found that it was necessary make multiple-round mappings with different mismatch...
Emerging evidence indicates that microRNAs (miRNAs) are often dysregulated and play a fundamental role in hepatocellular carcinoma (HCC). However, the mechanism underlying miRNA dysregulation is still elusive. In present study, we adopted an integrated analysis strategy combining data from genome-wide methylated DNA immunoprecipitation chip expression microarray to study regulation of methylation on HCC. We first characterized 864 differentially regions (DMRs) located 236 between cancerous...
Essential oils (EO) are promising feed additives for their antibacterial, antioxidant, and immune-enhancing abilities with low toxicity. Carvacrol, thymol, cinnamaldehyde commonly used to synthesize EO. However, few studies focus on combining these three EO in early-weaned piglets. In the present study, 24 piglets weaned at 21 d of age were randomly divided into 2 groups (6 replicate pens per group, pen). The fed a basal diet (the control group) supplemented 400 mg/kg (a blend consisting...
// Cheng Xu 1, * , Xiaoqing Liu 2, 4, Yibo Geng 1 Qingran Bai 4 Changcun Pan Yu Sun Xin Chen Hai Yuliang Wu Peng Zhang Wenhao Wang Zhen Junting Zhaohui 3 Rui Yang Jenna Lewis Darell Bigner Fangping Zhao 5 Yiping He Yan Qin Shen 2 and Liwei Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China Center for Life Sciences, Stem Cell Biology Regenerative Medicine, School Tsinghua Pathology, Duke University Center, The Preston Robert Tisch Brain Tumor...
Gradient descent is the core and foundation of neural networks, gradient optimization heuristics have greatly accelerated progress in deep learning. Although these methods are simple effective, how they work remains unknown. learning has become a hot research topic. Some efforts tried to combine multiple assist network training, but seem be more empirical, without theoretical guides. In this paper, framework proposed illustrate principle combining different by analyzing several adaptive...
Breast milk (BM) is the optimal nutrition source for infants, providing highly digestible proteins. In contrast, digestibility of proteins in infant formula (IF) varies, influenced by differences such as α-lactalbumin (α-La) and β-casein (β-CN). This study aimed to evaluate true ileal (TID) amino acids (AAs) BM IF with varying α-La β-CN contents using neonatal piglets. Twenty-four 11-day-old piglets (4 groups; 6 replicates/group) received either a nitrogen-free diet, (high (HIF) 1.74 g/100...
The intestine is the largest immune and barrier organ in body, diarrhea even death during piglet development are related to dysfunction caused by intestinal damage inflammation. A water-soluble β-glucan produced Agrobacterium ZX09 has been shown have a beneficial effect on gastrointestinal health. main objective of this study was investigate whether pre-feeding protective LPS-induced stress piglets. In study, 24 weaned piglets (21-day-old; 6.64 ± 0.16 kg) were assigned 4 treatments two ×...
Beta-glucan has been shown to have a beneficial effect on gastrointestinal health. This experiment was conducted investigate the effects of β-glucan isolated from Agrobacterium sp. ZX09 growth performance and intestinal health weaning pigs. A total 108 weaned pigs (21 d age; 6.05 ± 0.36 kg) were randomly divided into 3 groups (6 pens/group; 6 pigs/pen), each treated with following diets: 1) basal diet, 2) diet supplemented 20 mg/kg olaquindox, 3) 200 β-glucan, for 21 d. Compared control...
Numerous studies suggest that long non-coding RNAs (lncRNAs) participate in the biological process of diverse malignancies, including glioma. Although many differentially expressed lncRNAs have been identified glioma, to our best knowledge, role LINC00662 and its potential underlying mechanism glioma progression remains unclear. This study aimed explore function regulatory network glioma.Expressions LINC00662, miR-34a-5p lectin mannose-binding 2-like (LMAN2L) tissues were analyzed using The...
This study aimed to investigate the effect of stevia residue (STER) on production performance, egg quality and nutrition, antioxidant ability, immune responses, gut morphology microbiota laying hens during peak period. A total 270 Yikoujingfen NO.8 (35 weeks age) were randomly divided into 5 treatments. The control group fed a basial diet groups supplemented with 2%, 4%, 6% 8% STER. results showed that STER significantly increased production, content amino acids (alanine, proline, valine,...